ampi syrup - Ampicillin (125mg) medicine

Ampi Syrup (Ampicillin 125mg) - Uses, Price, Side Effects

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๐Ÿญ Shalina Laboratories Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is ampi syrup used for?

Ampi Syrup contains Ampicillin 125mg, a penicillin-type antibiotic used to treat bacterial infections such as respiratory tract infections, urinary tract infections, and meningitis. It works by inhibiting bacterial cell wall synthesis, leading to bacterial death. It is effective against both gram-positive and gram-negative bacteria.

  • Generic Name: Ampicillin
  • Manufacturer: Shalina Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š ampi syrup Uses & Benefits

Respiratory tract infections, urinary tract infections, meningitis, septicemia, endocarditis, skin and soft tissue infections.

Off-label uses: Prophylaxis for bacterial endocarditis, Lyme disease

๐Ÿ“‹ Drug Information

Generic Name(s)Ampicillin
Brand NameAmpilin
ManufacturerShalina Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCell wall active agent -Extended spectrum Penicillin
Route of AdministrationIntramuscular (IM) or Intravenous (IV)
StorageStore at 20-25ยฐC (68-77ยฐF); reconstituted solution stable for 1 hour at room temperature.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after intramuscular injection; oral absorption is variable but not applicable for injection.
DistributionDistributes widely into body tissues and fluids, including cerebrospinal fluid (inflamed meninges).
Protein Binding15-25%
MetabolismPartially metabolized in the liver to penicilloic acid.
Half-Life1-1.8 hours (prolonged in renal impairment)
ExcretionPrimarily excreted unchanged in urine (90%) via glomerular filtration and tubular secretion.
Bioavailability100% (IM/IV)
Onset of ActionRapid (within minutes after IV)
Peak Plasma Time30-60 minutes after IM injection
Duration of Action6-8 hours

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis.

Mechanism Steps

1Binds to penicillin-binding proteins (PBPs) on bacterial cell wall
2Inhibits transpeptidase activity, preventing cross-linking of peptidoglycan
3Activates autolytic enzymes (autolysins) in bacterial cell wall

๐Ÿ’ก How to Take ampi syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โœ… ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of ampi syrup

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Injection site pain

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Pseudomembranous colitis
  • Seizures
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Interstitial nephritis
  • Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Methotrexate Major Increased methotrexate toxicity
Warfarin Moderate Increased bleeding risk
Probenecid Moderate Decreased renal excretion of ampicillin

๐Ÿšจ Major Interactions

  • Methotrexate
  • Warfarin
  • Oral contraceptives
  • Probenecid

โšก Moderate Interactions

  • Allopurinol
  • Aminoglycosides
  • Chloramphenicol

โ„น๏ธ Minor Interactions

  • Tetracyclines
  • Sulfonamides

๐Ÿฝ๏ธ Food Interactions

No significant food interactions with injection

๐Ÿท Alcohol Interaction

No direct interaction, but alcohol may reduce immune response.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Moderate
Heart
Low
Pregnancy
Category B

๐Ÿšซ Contraindications

Hypersensitivity to penicillins, cephalosporins, or any component of the formulation.

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, CBC, signs of hypersensitivity, superinfection.

๐Ÿคฑ Lactation Safety

Compatible; excreted in small amounts in breast milk, unlikely to harm infant.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may help remove ampicillin.

โฐ Missed Dose

Administer as soon as possible; skip if almost time for next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for ampi syrup

View All

Alternative brands with exact same active ingredient (Ampicillin (125mg)):

Medical Note: Always consult your doctor before switching medications.

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