among 6-dsr 30mg/40mg tablet - Uses, Price, Side Effects & Substitutes
What is among 6-dsr 30mg/40mg tablet used for?
Anleo-DSR Capsule (Domperidone + Pantoprazole) is used to treat GASTRO INTESTINAL. It contains Domperidone (30mg) + Pantoprazole (40mg), which Domperidone is a dopamine D2 receptor antagonist that enhances gastric motility . Always consult your doctor before use. Take as prescribed.
- Generic Name: Domperidone + Pantoprazole
- Manufacturer: Lewis Bioserch Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ among 6-dsr 30mg/40mg tablet Uses & Benefits
Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, peptic ulcer disease, Zollinger-Ellison syndrome (pantoprazole component).
Off-label uses: Domperidone: Lactation stimulation (not approved in many countries); Pantoprazole: Prevention of stress ulcers, eosinophilic esophagitis.
๐ Drug Information
| Generic Name(s) | Domperidone + Pantoprazole |
| Brand Name | Anleo-DSR Capsule |
| Manufacturer | Lewis Bioserch Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Domperidone is a dopamine D2 receptor antagonist that enhances gastric motility and accelerates gastric emptying. Pantoprazole is a proton pump inhibitor that irreversibly inhibits H+/K+ ATPase in gastric parietal cells, reducing gastric acid secretion.
Mechanism Steps
๐ก How to Take among 6-dsr 30mg/40mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of among 6-dsr 30mg/40mg tablet
โ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Flatulence
- Dry mouth
- Dizziness
๐จ Serious Side Effects
- QT prolongation
- Ventricular arrhythmias
- Extrapyramidal symptoms (domperidone)
- Clostridium difficile infection
- Bone fracture (long-term)
- Hypomagnesemia
- Interstitial nephritis
โ ๏ธ Rare Side Effects
- Gynecomastia
- Galactorrhea
- Jaundice
- Hepatitis
- Anaphylaxis
- Stevens-Johnson syndrome
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased risk of QT prolongation |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Sucralfate | Minor | Reduced absorption of pantoprazole |
๐จ Major Interactions
- Ketoconazole
- Itraconazole
- Voriconazole
- Clarithromycin
- Erythromycin
- Ritonavir
- Saquinavir
- Amiodarone
- Quinidine
- Methotrexate
โก Moderate Interactions
- Warfarin
- Cilostazol
- Citalopram
- Escitalopram
- Fluoxetine
- Paroxetine
- Sertraline
- Tacrolimus
- Cyclosporine
- Digoxin
โน๏ธ Minor Interactions
- Sucralfate
- Antacids
- Iron supplements
- Calcium carbonate
๐ฝ๏ธ Food Interactions
Food delays absorption of domperidone; pantoprazole should be taken before meals for optimal effect.
๐ท Alcohol Interaction
Alcohol may worsen gastrointestinal irritation and reduce drug efficacy.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component; gastrointestinal hemorrhage, obstruction, or perforation; prolactinoma; concurrent use with strong CYP3A4 inhibitors (e.g., ketoconazole) causing QT prolongation; severe hepatic impairment.
๐ Monitoring Parameters
Liver function tests, ECG (QT interval), serum electrolytes, magnesium levels (long-term use), renal function.
๐คฑ Lactation Safety
Domperidone is excreted in breast milk; pantoprazole is excreted in small amounts. Caution advised.
๐ Overdose Management
Supportive care; domperidone overdose may cause extrapyramidal symptoms; pantoprazole overdose unlikely to cause serious effects.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next dose; do not double dose.