What is alpuric 100mg tablet used for?

This medicine contains Allopurinol 100mg, which is used to lower high uric acid levels in the body. It helps prevent gout attacks and kidney stones caused by uric acid. It works by blocking an enzyme called xanthine oxidase. It is taken orally, usually once daily after food. It is not a painkiller and should not be used during an acute gout attack.

Generic Name: Allopurinol
Manufacturer: Carise Pharmaceuticals Pvt Ltd
Form: Allopathy
Pregnancy Category: Consult doctor
Prescription Required: Yes

🇮🇳 alpuric 100mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलोप्यूरिनॉल 100 मिलीग्राम टैबलेट है, जिसका उपयोग गाउट और यूरिक एसिड के स्तर को कम करने के लिए किया जाता है। यह शरीर में यूरिक एसिड बनाने वाले एंजाइम को रोकती है, जिससे गाउट के दौरे और किडनी में पथरी की संभावना कम होती है। यह दवा दर्द निवारक नहीं है और गाउट के तीव्र दौरे के दौरान नहीं लेनी चाहिए। इसे डॉक्टर के परामर्श से ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द और चक्कर आना शामिल हैं। कभी-कभी त्वचा पर दाने हो सकते हैं, जिन्हें तुरंत डॉक्टर को बताना चाहिए। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें त्वचा की गंभीर प्रतिक्रियाएं, लीवर की सूजन, और रक्त विकार शामिल हो सकते हैं। कोई भी असामान्य लक्षण दिखने पर डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पर्याप्त पानी पिएं। शराब का सेवन न करें। अगर आपको किडनी या लीवर की बीमारी है, तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को बच्चों से दूर रखें। इसे कमरे के तापमान पर सूखी जगह पर रखें।

💊 alpuric 100mg tablet Uses & Benefits

[{"condition":"Gout","description":"Used to prevent recurrent gout attacks by lowering blood uric acid levels and preventing uric acid crystal deposition in joints.","evidence":"Well-established"},{"condition":"Hyperuricemia","description":"Used to treat high uric acid levels in the blood, which can lead to gout and kidney stones.","evidence":"Well-established"},{"condition":"Uric acid kidney stones","description":"Helps prevent the formation of uric acid kidney stones by reducing uric acid production.","evidence":"Well-established"},{"condition":"Tumor lysis syndrome","description":"Used to prevent high uric acid levels that can occur during cancer treatment, especially in patients with certain cancers.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Angina pectoris","description":"Sometimes studied for potential benefits in angina, but not a standard use.","evidence":"Limited"},{"condition":"Inflammatory bowel disease","description":"Occasionally explored for anti-inflammatory effects, but evidence is insufficient.","evidence":"Limited"}]

Primary treatment for: Gout

Also treats: Hyperuricemia, Uric acid kidney stones, Tumor lysis syndrome

📋 Drug Information

Generic Name(s)	Allopurinol
Brand Name	Alnol
Manufacturer	Carise Pharmaceuticals Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	PAIN ANALGESICS
Action Class	Xanthine oxidase Inhibitors-gout
Route of Administration	Oral
Storage	Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and direct sunlight. Keep in the original container, tightly closed.
Shelf Life	24 months from the date of manufacture. Do not use after the expiry date printed on the pack.
WHO Guideline	Not established from the available information. Guidelines from other organizations may recommend allopurinol for gout management.
ICMR Guideline	Not established from the available information. Consult local guidelines for gout management.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1

Take this medicine after a meal to reduce stomach upset.

2

Drink plenty of water throughout the day to prevent kidney stones.

3

Avoid alcohol while taking this medicine, as it can increase uric acid levels.

4

Do not start this medicine during an acute gout attack; wait until the attack resolves.

5

Report any skin rash immediately, as it may be a sign of a serious reaction.

6

Continue taking this medicine even if you feel well, as it prevents future gout attacks.

7

Regular monitoring of uric acid, liver, and kidney function is important.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅

Recurrent gout attacks

This medicine is commonly prescribed to prevent gout attacks.

Likely Use

✅

High uric acid levels

This medicine is used to lower uric acid levels.

Likely Use

❌

Acute gout pain

This medicine is not a painkiller and is not used during an acute attack.

Not Primary

❌

Fever

This medicine is not a primary fever reducer.

Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the gastrointestinal tract. The exact bioavailability is not established from the available information.

DistributionThis medicine is distributed widely throughout the body, including into the liver, kidneys, and joints. It crosses the blood-brain barrier to some extent. The volume of distribution is not established from the available information.

Protein BindingThis medicine is approximately 20% bound to plasma proteins. The exact binding characteristics are not established from the available information.

MetabolismThis medicine is metabolized in the liver to oxypurinol, which is also pharmacologically active. Oxypurinol is primarily responsible for the long duration of action of this medicine.

Half-LifeThe elimination half-life of this medicine is approximately 1 to 2 hours, while its active metabolite oxypurinol has a half-life of approximately 15 to 20 hours. The exact values may vary based on individual factors.

ExcretionThis medicine and its metabolites are primarily excreted by the kidneys. About 70% of a dose is excreted in the urine as oxypurinol. Renal impairment can prolong the elimination of oxypurinol.

BioavailabilityThe bioavailability of this medicine is approximately 80% when taken orally. The exact value may vary.

Onset of ActionThe onset of action for lowering uric acid levels is gradual, typically taking 1 to 2 weeks to observe a significant reduction. The full effect may take several weeks.

Peak Plasma TimeThe peak plasma time for this medicine is approximately 1.5 to 2 hours after oral administration. The peak for oxypurinol occurs later, around 4 to 6 hours.

Duration of ActionThe duration of action is prolonged due to the active metabolite oxypurinol, which has a long half-life. The uric acid-lowering effect lasts for approximately 24 hours or more after a single dose.

How It Works

This medicine works by inhibiting the enzyme xanthine oxidase. Xanthine oxidase is responsible for converting hypoxanthine to xanthine and then to uric acid. By blocking this enzyme, this medicine reduces the production of uric acid in the body. This leads to lower blood uric acid levels, which helps prevent the formation of uric acid crystals in joints and kidneys. These crystals are responsible for the pain and inflammation seen in gout. This medicine does not relieve pain during an acute gout attack; it is used to prevent future attacks.

Mechanism Steps

1

Inhibition of xanthine oxidase: This medicine binds to and inhibits the enzyme xanthine oxidase, blocking the conversion of hypoxanthine to xanthine and xanthine to uric acid.

2

Reduced uric acid production: As a result of enzyme inhibition, the production of uric acid in the body is decreased.

3

Lower serum uric acid levels: With less uric acid being produced, blood levels of uric acid gradually decrease.

4

Prevention of crystal formation: Lower uric acid levels prevent the formation and deposition of uric acid crystals in joints and kidneys, reducing gout attacks and kidney stones.

💡 How to Take alpuric 100mg tablet

Strength: Allopurinol 100 mg immediate-release tablet

1Take this medicine orally with a full glass of water.

2Take it after a meal to reduce stomach upset.

3Swallow the tablet whole; do not crush or chew.

4Take it at the same time each day to maintain consistent levels.

5Do not take more than the prescribed dose.

6If you miss a dose, follow the missed dose instructions.

7Continue taking the medicine even if you feel well, as it prevents gout attacks.

Dosage Information

Adult Dosage	The usual adult dose of this medicine for gout or hyperuricemia is 100 mg to 300 mg per day, taken orally, often as a single daily dose after a meal. The dose may be gradually increased based on serum uric acid levels. For tumor lysis syndrome, higher doses may be used under medical supervision. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric Dosage	Pediatric dosing is not established from available information. Consult a pediatrician.
Elderly Dosage	Elderly patients may have reduced kidney function and may require lower doses. Dose should be individualized based on renal function. Consult your doctor for appropriate dosing.
Renal Impairment	In patients with kidney impairment, the dose of this medicine should be reduced based on creatinine clearance. For creatinine clearance below 60 mL/min, a lower starting dose is recommended. Regular monitoring of kidney function is advised. Consult your doctor for dose adjustment.
Hepatic Impairment	In patients with liver impairment, this medicine should be used with caution. Dose reduction may be necessary. Regular monitoring of liver function is recommended. Consult your doctor for appropriate dosing.
Maximum Daily Dose	The maximum recommended daily dose is 800 mg, but doses above 300 mg are rarely used except in specific conditions like tumor lysis syndrome. The dose should not exceed the prescribed amount.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food

Take with meals

Reduces stomach upset.

Alcohol

Avoid

Increases uric acid levels and reduces medicine effectiveness.

High-purine foods

Limit intake

Can increase uric acid levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed

→ Take the missed dose as soon as you remember.

💡 Continue with the regular schedule.

📌 More than half the dosing interval has passed

→ Skip the missed dose.

💡 Do not double dose to catch up.

⚠️ Side Effects of alpuric 100mg tablet

✅ Common Side Effects

Nausea (Common (1-10%))

Take with food to reduce nausea. If it persists, consult your doctor.

Diarrhea (Common (1-10%))

Stay hydrated. If diarrhea is severe or persistent, contact your doctor.

Headache (Common (1-10%))

Rest and stay hydrated. Consult your doctor if headaches are severe or persistent.

Dizziness (Common (1-10%))

Avoid driving or operating machinery until you know how this medicine affects you.

Skin rash (Uncommon (0.1-1%))

Stop taking the medicine and contact your doctor immediately if a rash appears.

🚨 Serious Side Effects

Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) (Rare (<0.1%))

Seek immediate medical attention if you develop a rash, blisters, peeling skin, or sores in the mouth or eyes.

Liver inflammation (hepatitis) (Rare (<0.1%))

Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.

Kidney problems (Rare (<0.1%))

Inform your doctor if you notice decreased urine output or swelling.

Blood disorders (e.g., agranulocytosis, thrombocytopenia) (Rare (<0.1%))

Report unusual bruising, bleeding, fever, or sore throat to your doctor immediately.

Hypersensitivity reactions (Rare (<0.1%))

Seek emergency help if you experience swelling of the face, lips, tongue, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Peripheral neuropathy

Report numbness, tingling, or weakness in the limbs to your doctor.

Cataracts

Regular eye check-ups are recommended if you are on long-term therapy.

Alopecia

Consult your doctor if you notice unusual hair loss.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug	Severity	Effect
Azathioprine	Major
Mercaptopurine	Major
Warfarin	Major
Thiazide diuretics	Moderate
Ampicillin	Moderate
ACE inhibitors	Moderate
Antacids	Minor
Iron supplements	Minor

🚨 Major Interactions

Azathioprine
Mercaptopurine
Warfarin

⚡ Moderate Interactions

Thiazide diuretics
Ampicillin
ACE inhibitors

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine. Alcohol can increase uric acid levels and may reduce the effectiveness of this medicine. It can also increase the risk of liver problems. If you drink alcohol, talk to your doctor about safe limits.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to allopurinol or any component of the formulation","Previous severe skin reaction to allopurinol","Acute gout attack (should not be started during an attack)","Severe liver disease","Severe kidney disease (dose adjustment required)"]

⚠️ Warnings & Precautions

["Serious skin reactions can occur; stop the medicine and seek immediate medical attention if a rash develops.","Use with caution in patients with kidney or liver disease; dose adjustment may be needed.","May cause drowsiness or dizziness; avoid driving or operating machinery until you know how it affects you.","Drink plenty of fluids to prevent kidney stones.","Avoid alcohol while taking this medicine.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not use this medicine to treat an acute gout attack; it is for prevention.","Regular monitoring of blood counts, liver, and kidney function is recommended."]

🤱 Lactation Safety

This medicine passes into breast milk. It is not recommended during breastfeeding unless clearly needed. Consult your doctor before breastfeeding while on this medicine.

💊 Overdose Management

If you suspect an overdose, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, dizziness, and diarrhea. Treatment is supportive and symptomatic. There is no specific antidote. Contact a poison control center or emergency room right away.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor. Drink plenty of water throughout the day to help prevent kidney stones. Avoid alcohol while taking this medicine, as it can increase uric acid levels and reduce the effectiveness of the medicine. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Inform your doctor if you have kidney or liver disease, heart problems, or if you are pregnant or breastfeeding. This medicine may make you feel dizzy or drowsy; avoid driving or operating heavy machinery until you know how it affects you. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight. Do not share this medicine with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function and may require lower doses. Regular monitoring of kidney function is important. They may also be more susceptible to side effects. Consult your doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

Not established from the available information. Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. They will advise you on whether to continue or temporarily stop it.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. There are no specific precautions, but it is important for your dentist to know your complete medication history.

💚 Lifestyle Tips for Better Results

🏃

Maintain a healthy weight to reduce stress on joints.

🥗

Stay well hydrated by drinking plenty of water.

😴

Limit alcohol consumption, especially beer.

💧

Avoid high-purine foods such as red meat, organ meats, and seafood.

🧘

Engage in regular low-impact exercise like walking or swimming.

🌞

Follow a balanced diet rich in fruits and vegetables.

🏋️ Exercise Considerations

This medicine may cause dizziness in some people. Avoid strenuous exercise or activities requiring alertness until you know how the medicine affects you. Regular low-impact exercise is generally safe and beneficial for gout.

🥗 Diet Recommendations

Drink at least 8-10 glasses of water daily.

Limit intake of red meat, organ meats, and seafood.

Avoid alcohol, especially beer.

Include low-fat dairy products.

Eat plenty of fruits and vegetables.

Maintain a healthy weight.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it should not significantly impact your daily activities. Continue taking it as prescribed.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Stopping suddenly can lead to a gout flare. Your doctor may adjust or stop the medicine based on your uric acid levels and overall health. If you experience a serious side effect, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe and effective for managing gout and hyperuricemia. Regular monitoring of uric acid levels, liver function, kidney function, and blood counts is recommended. Rarely, long-term use may be associated with cataracts or peripheral neuropathy. Do not stop taking this medicine without consulting your doctor, as stopping suddenly can lead to gout flares.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Reducing purine intake can help lower uric acid levels.

Evidence: Well-established

Weight loss

Losing excess weight can reduce uric acid levels and gout attacks.

Evidence: Well-established

Other urate-lowering medicines

Febuxostat or probenecid may be alternatives if allopurinol is not suitable.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information. There are no known interactions between this medicine and vaccines. Consult your doctor for specific advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from moisture. If crossing time zones, continue taking your dose at the usual time or as advised by your doctor. Check customs regulations for carrying prescription medicines. Always carry enough supply for your trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with recurrent gout attacks

He was prescribed this medicine after his uric acid levels were found to be high. He started with 100 mg daily after breakfast. After a few weeks, his uric acid levels decreased, and he experienced fewer gout attacks. He made sure to drink plenty of water and avoided alcohol. He reported mild nausea initially, which went away after taking the medicine with food.

💡 Lesson: Taking this medicine with food and staying hydrated can improve tolerability and effectiveness.

👤 A 62-year-old woman with a history of kidney stones

She had multiple episodes of uric acid kidney stones. Her doctor prescribed this medicine to prevent further stones. She was advised to increase her water intake. Over six months, she did not have any new stones. She also had regular blood tests to monitor her kidney function and uric acid levels.

💡 Lesson: This medicine can effectively prevent uric acid kidney stones when combined with good hydration and regular monitoring.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering uric acid levels within 1 to 2 weeks, but it may take several weeks to achieve the full effect. It is important to continue taking it as prescribed.

Q: Can I take this medicine during a gout attack?

A: No, this medicine is not used to treat an acute gout attack. It is used to prevent future attacks. If you are already taking it and have an attack, continue taking it and consult your doctor for pain relief.

Q: What should I avoid while taking this medicine?

A: Avoid alcohol and high-purine foods. Drink plenty of water. Do not take this medicine without consulting your doctor if you have kidney or liver disease.

Q: Is this medicine safe for long-term use?

A: Yes, it is generally safe for long-term use when taken as prescribed and with regular monitoring of uric acid, liver, and kidney function.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

Can I take this medicine long-term?
Will it affect my kidney function?
Can I drive after taking this medicine?
Does it interact with my blood pressure medicine?
What if I miss a dose?
Can I drink alcohol while taking this?

🔄 Substitutes for alpuric 100mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

Myth: This medicine can be used to treat an acute gout attack.
Fact: This medicine is not a painkiller and does not relieve acute gout pain. It is used to prevent future attacks.
Myth: You can stop taking this medicine once your uric acid levels are normal.
Fact: You should continue taking this medicine as prescribed, even if you feel well, to prevent gout attacks.
Myth: This medicine causes kidney damage in everyone.
Fact: Kidney problems are rare and can be prevented by drinking plenty of water and monitoring kidney function.

🔄 Alternative Options

Generic Alternatives

Allopurinol 100 mg tablet

Brand Alternatives

Alnol 100mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Allopurinol","class":"Xanthine oxidase inhibitor","route":"Oral","common_use":"Gout prevention","notes":"First-line, inexpensive, requires renal dose adjustment."},{"medicine":"Febuxostat","class":"Xanthine oxidase inhibitor","route":"Oral","common_use":"Gout prevention","notes":"Alternative for those intolerant to allopurinol; may have cardiovascular warnings."},{"medicine":"Probenecid","class":"Uricosuric agent","route":"Oral","common_use":"Gout prevention","notes":"Increases uric acid excretion; not effective in renal impairment."}]

Alnol 100mg Tablet: Complete Medicine Guide

When to Call Your Doctor IMMEDIATELY

What is alpuric 100mg tablet used for?

🇮🇳 alpuric 100mg tablet के बारे में (Hindi Summary)

💊 alpuric 100mg tablet Uses & Benefits

📋 Drug Information

👨‍⚕️ Doctor's Practical Tips

🔍 Is This Medicine Right for Your Symptom?

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take alpuric 100mg tablet

Dosage Information

Dosage Timeline

🍽️ Food Timing Guide

⏰ What to Do If You Miss a Dose

⚠️ Side Effects of alpuric 100mg tablet

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

🍷 Alcohol Interaction

🔎 Check Your Other Medicines

🛡️ Safety & Warnings

🚫 Contraindications

⚠️ Warnings & Precautions

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

Additional Safety Advice

👴 Special Considerations for Elderly

💡 For Patients Above 65

🤰 Pregnancy Planning (TTC)

🏥 Post-Surgery Considerations

🦷 Dental Procedures

💚 Lifestyle Tips for Better Results

🏋️ Exercise Considerations

🥗 Diet Recommendations

💼 Impact on Daily Work & Life

🛑 When to Stop This Medicine

📅 Long-Term Use Effects

🌿 Non-Medicine Approaches

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

📦 Storage Guide

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✈️ Traveling with This Medicine

💰 Cost Analysis & Savings

👥 Real Patient Stories

💬 Questions Patients Often Ask

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

🔄 Substitutes for alpuric 100mg tablet

🛑 Myths vs. Facts

🔄 Alternative Options

Generic Alternatives

Brand Alternatives

📊 Comparison with Similar Medicines

😊 Was this information helpful?

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