alpreg 200mg capsule - Progesterone (Natural Micronized) (200mg) medicine

Angest 200mg Soft Gelatin Capsule: Complete Medicine Guide

No reviews yet
🏭 Almet Corporation Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category This medicine is used to support pregnancy and is considered safe when used as prescribed. It is not associated with an increased risk of birth defects. However, consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden shortness of breath or chest pain
  • Swelling or pain in one leg
  • Severe allergic reaction (rash, itching, swelling of face, lips, throat)
  • Yellowing of skin or eyes
  • Heavy or unusual vaginal bleeding
  • Severe abdominal pain

If experiencing severe symptoms, call emergency services immediately.

What is alpreg 200mg capsule used for?

This medicine is a natural micronized progesterone used to support pregnancy, treat menstrual disorders, and prevent preterm birth. It works by binding to progesterone receptors and is taken as prescribed by a doctor.

  • Generic Name: Progesterone (Natural Micronized)
  • Manufacturer: Almet Corporation Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alpreg 200mg capsule के बारे में (Hindi Summary)

उपयोग: यह दवा प्राकृतिक माइक्रोनाइज्ड प्रोजेस्टेरोन का 200 मिलीग्राम कैप्सूल है। इसका उपयोग महिलाओं में प्रोजेस्टेरोन की कमी से होने वाली समस्याओं के इलाज के लिए किया जाता है। यह गर्भधारण में सहायता करती है, समय से पहले प्रसव को रोकती है, और मासिक धर्म की अनियमितताओं को ठीक करती है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, सिरदर्द, स्तनों में कोमलता, मतली और पेट में सूजन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें रक्त के थक्के, गंभीर एलर्जी, या यकृत की समस्या हो सकती है। कोई भी गंभीर लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। अन्य दवाओं के साथ इसका सेवन करने से पहले डॉक्टर को बताएं। इसे ठंडी और सूखी जगह पर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 alpreg 200mg capsule Uses & Benefits

[{"condition":"Luteal phase support in assisted reproduction","description":"This medicine is used to support the luteal phase in women undergoing in vitro fertilization (IVF) or other assisted reproductive technologies to improve implantation and pregnancy rates.","evidence":"Well-established"},{"condition":"Prevention of preterm birth","description":"This medicine may be prescribed to women with a history of preterm birth or short cervix to reduce the risk of premature delivery.","evidence":"Well-established"},{"condition":"Secondary amenorrhea","description":"This medicine is used to treat absence of menstruation due to hormonal imbalance when progesterone is deficient.","evidence":"Well-established"},{"condition":"Abnormal uterine bleeding","description":"This medicine helps regulate abnormal uterine bleeding caused by hormonal imbalance.","evidence":"Well-established"},{"condition":"Endometrial protection during estrogen therapy","description":"This medicine is used in combination with estrogen therapy in postmenopausal women to protect the endometrium from hyperplasia.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Luteal phase defect","description":"Sometimes prescribed off-label to treat luteal phase defect in women with infertility.","evidence":"Limited"},{"condition":"Catamenial epilepsy","description":"Occasionally used off-label to reduce seizure frequency in women with catamenial epilepsy.","evidence":"Limited"}]

Primary treatment for: Progesterone deficiency

Also treats: Infertility, Preterm birth risk, Secondary amenorrhea, Abnormal uterine bleeding

📋 Drug Information

Generic Name(s)Progesterone (Natural Micronized)
Brand NameAqsusten 25 Solution for Injection
ManufacturerAlmet Corporation Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassNatural Progesterone
Route of AdministrationIntramuscular
StorageStore at room temperature (15-30°C) away from moisture and heat. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at bedtime to minimize drowsiness during the day.
2
Always take this medicine with food to improve absorption and reduce nausea.
3
Do not drive or operate heavy machinery until you know how this medicine affects you.
4
Inform your doctor if you have a history of blood clots, liver disease, or depression.
5
Do not stop taking this medicine abruptly without consulting your doctor.
6
Keep all your follow-up appointments for monitoring.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Irregular menstrual bleeding
This medicine is commonly prescribed for this.
Likely Use
✅
History of preterm birth
This medicine may be prescribed to prevent preterm birth.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the gastrointestinal tract after oral administration. Micronization increases its surface area and improves absorption. When taken with food, absorption is enhanced.
DistributionThis medicine is highly lipophilic and distributes widely into body tissues, including the uterus, breast, and brain. It crosses the blood-brain barrier and is excreted in breast milk.
Protein BindingThis medicine is approximately 96-99% bound to plasma proteins, primarily albumin and corticosteroid-binding globulin.
MetabolismThis medicine is metabolized primarily in the liver by cytochrome P450 enzymes, mainly CYP3A4, into several metabolites including pregnanediol and pregnanolone.
Half-LifeThe elimination half-life of this medicine is approximately 5-20 hours, depending on the route of administration and individual factors.
ExcretionThis medicine and its metabolites are excreted mainly in the urine as glucuronide and sulfate conjugates, with a small amount in feces.
BioavailabilityThe oral bioavailability of this medicine is variable but increases when taken with food. Micronized formulations have improved bioavailability compared to non-micronized forms.
Onset of ActionThe onset of action varies depending on the indication. For luteal support, effects on the endometrium may be seen within a few days. For sedation, onset is within 1-2 hours.
Peak Plasma TimePeak plasma concentrations of this medicine are reached approximately 1-3 hours after oral administration.
Duration of ActionThe duration of action of this medicine is typically 24 hours or more, depending on the dose and individual response.

How It Works

This medicine works by binding to and activating progesterone receptors in the nucleus of target cells. This binding leads to changes in gene expression that prepare the endometrium for implantation, maintain pregnancy, and regulate the menstrual cycle. It also has anti-estrogenic effects on the endometrium and can suppress ovulation at higher doses.

Mechanism Steps

1
Binding to progesterone receptor: This medicine diffuses into target cells and binds to the progesterone receptor in the cytoplasm or nucleus.
2
Receptor activation and dimerization: Upon binding, the receptor undergoes a conformational change, dimerizes, and becomes activated.
3
Gene transcription modulation: The activated receptor complex binds to progesterone response elements in DNA, modulating the transcription of specific genes.
4
Physiological effects: This leads to secretory changes in the endometrium, relaxation of uterine muscle, and other progesterone-like effects.

💡 How to Take alpreg 200mg capsule

Strength: 200 mg soft gelatin capsule

1Take this medicine exactly as prescribed by your doctor.
2Swallow the capsule whole with a glass of water.
3Take with food to improve absorption and reduce nausea.
4Take at the same time each day to maintain consistent levels.
5If you miss a dose, follow the missed dose instructions.
6Do not crush or chew the capsule.

Dosage Information

Adult DosageThe dose of this medicine is individualized by a qualified clinician based on the indication, age, weight, and clinical response. For luteal support, a common dose is 200-400 mg daily, often taken at bedtime. For prevention of preterm birth, 200 mg daily may be used. Always follow your doctor's prescription exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the sedative effects of this medicine. Use with caution and follow your doctor's advice.
Renal ImpairmentNo specific dose adjustment is recommended for renal impairment, but use with caution and monitor for side effects.
Hepatic ImpairmentThis medicine is metabolized in the liver. Use with caution in patients with hepatic impairment. Dose adjustment may be necessary.
Maximum Daily DoseThe maximum daily dose should not exceed 600 mg unless directed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Increases absorption and reduces nausea.
Grapefruit
Avoid
May increase drug levels by inhibiting metabolism.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alpreg 200mg capsule

✅ Common Side Effects

Drowsiness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you. Taking at bedtime may help.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. If persistent, consult your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe or persistent.
Breast tenderness (Common (5-10%))
Wear a supportive bra. Consult doctor if severe.
Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if persistent.
Abdominal bloating (Common (5-10%))
Eat small frequent meals. Consult doctor if severe.

🚨 Serious Side Effects

Blood clots (thromboembolism) (Rare (<0.1%))
Seek immediate medical attention if you experience sudden shortness of breath, chest pain, or swelling in legs.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you notice rash, itching, swelling of face, lips, or throat, or difficulty breathing.
Liver problems (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Unusual vaginal bleeding (Rare (<0.1%))
Consult your doctor if you experience heavy or unusual vaginal bleeding.

⚠️ Rare Side Effects

Depression
Seek medical advice if you feel persistently sad or hopeless.
Seizures
Seek immediate medical attention.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ketoconazole Major
Rifampin Major
Insulin Moderate
Furosemide Moderate
Grapefruit juice Minor

🚨 Major Interactions

  • Anticoagulants (e.g., warfarin)
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)

⚡ Moderate Interactions

  • Antidiabetic drugs
  • Diuretics

🍷 Alcohol Interaction

Alcohol may increase the sedative effects of this medicine. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to progesterone or any component of this medicine","Undiagnosed vaginal bleeding","Severe liver disease","History of blood clots (thromboembolism)","Known or suspected breast cancer","Missed abortion"]

⚠️ Warnings & Precautions

["This medicine may cause drowsiness. Avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with a history of depression.","This medicine may cause fluid retention. Use with caution in patients with heart or kidney disease.","Inform your doctor if you have a history of blood clots.","This medicine should not be used as a contraceptive.","Do not share this medicine with others."]

🤱 Lactation Safety

This medicine is excreted in breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose of this medicine may cause drowsiness, dizziness, and nausea. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. This medicine may cause drowsiness; avoid driving or operating heavy machinery until you know how it affects you. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Tell your doctor about all other medicines you are taking, especially anticoagulants, antifungals, and HIV medications, as they may interact with this medicine. Store this medicine at room temperature away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the sedative effects. Use with caution and follow your doctor's advice.

🤰 Pregnancy Planning (TTC)

This medicine is often used to support pregnancy. If you are planning pregnancy, consult your doctor for appropriate timing and dosage.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may affect blood clotting and interact with anesthetic agents.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may increase bleeding risk during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight.
🥗
Engage in regular low-impact exercise.
😴
Practice good sleep hygiene.
💧
Include a balanced diet rich in fruits and vegetables.
🧘
Avoid smoking and excessive alcohol.

🏋️ Exercise Considerations

This medicine may cause drowsiness or dizziness. Avoid strenuous exercise until you know how it affects you.

🥗 Diet Recommendations

Take with food to improve absorption.
Avoid grapefruit juice.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Plan your tasks accordingly until you know how it affects you.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Your doctor will advise you on when and how to stop based on your condition.

📅 Long-Term Use Effects

Long-term use of this medicine may require monitoring of liver function and signs of blood clots. It is generally well-tolerated when used as prescribed. Regular follow-up with your doctor is recommended.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Healthy diet and exercise can complement medical therapy.

Evidence: Well-established
Other progesterone formulations

Alternative routes or formulations may be considered based on your condition.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. Consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, adjust your dosing schedule gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman undergoing IVF treatment
She was prescribed this medicine for luteal phase support. She took it at bedtime with food as directed. She experienced mild drowsiness initially but it improved after a week. She successfully conceived and continued the medicine as advised by her doctor.
💡 Lesson: Taking this medicine at bedtime and with food helps manage side effects and improves compliance.
👤 A 28-year-old woman with a history of preterm birth
She was prescribed this medicine to prevent preterm birth in her second pregnancy. She took it daily as prescribed and delivered at full term. She reported mild breast tenderness but no other significant side effects.
💡 Lesson: Consistent use of this medicine as prescribed can help prevent preterm birth in at-risk women.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The onset of action varies depending on the indication. For luteal support, effects may be seen within a few days. For sedation, onset is within 1-2 hours.

Q: Can I take this medicine without food?

A: It is best to take this medicine with food to improve absorption and reduce nausea.

Q: Is this medicine safe during pregnancy?

A: This medicine is used to support pregnancy and is considered safe when used as prescribed. Consult your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my fertility?
  • Can I drive after taking this medicine?
  • Does it interact with my other medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for alpreg 200mg capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a contraceptive.
    Fact: This medicine is not a contraceptive and should not be used to prevent pregnancy.
  • Myth: This medicine can be taken without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Natural micronized progesterone 200 mg soft gelatin capsules

Brand Alternatives

  • Angest 200mg Soft Gelatin Capsule

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Natural micronized progesterone 200 mg","route":"Intramuscular","uses":"Luteal support, preterm birth prevention"},{"medicine":"Dydrogesterone","composition":"Dydrogesterone 10 mg","route":"Oral","uses":"Menstrual disorders, luteal support"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory