pregsure 200mg capsule - Progesterone (Natural Micronized) (200mg) medicine

Endogest 200 SR Tablet: Complete Guide to Uses, Side Effects, Dosage, and Safety

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🏭 Serene Life Sciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
🤰 Pregnancy Category This medicine is used to support pregnancy in specific situations and is generally considered acceptable when prescribed by a doctor. It is not classified under the old letter category system. The decision to use this medicine during pregnancy should be made by a qualified clinician based on the individual's condition and needs. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for luteal support, amenorrhea, abnormal uterine bleeding, and hormone replacement therapy in women with a uterus.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden swelling of the face, lips, tongue, or throat, or difficulty breathing.
  • Chest pain, sudden shortness of breath, or coughing up blood.
  • Pain, swelling, or redness in one leg, especially the calf.
  • Severe headache with vision changes, confusion, or weakness on one side of the body.
  • Yellowing of the skin or eyes, dark urine, or severe abdominal pain.
  • Heavy vaginal bleeding with large clots or dizziness and fainting.
  • Severe depression or thoughts of harming yourself.
  • High fever with a rash or severe allergic reaction.

If experiencing severe symptoms, call emergency services immediately.

What is pregsure 200mg capsule used for?

This medicine is an oral tablet containing natural micronized progesterone 200 mg. It is used to support pregnancy, treat menstrual problems, and protect the uterine lining during hormone replacement therapy. It works by binding to progesterone receptors in the body. Take it exactly as prescribed, usually at bedtime, and avoid driving until you know how it affects you.

  • Generic Name: Progesterone (Natural Micronized) (200mg)
  • Manufacturer: Serene Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 pregsure 200mg capsule के बारे में (Hindi Summary)

उपयोग: यह दवा प्राकृतिक माइक्रोनाइज़्ड प्रोजेस्टेरोन 200 मिलीग्राम की एक ओरल टैबलेट है। इसका इस्तेमाल मुख्य रूप से उन महिलाओं में किया जाता है जिनमें प्रोजेस्टेरोन हार्मोन की कमी होती है। यह गर्भावस्था को सहारा देने, माहवारी की समस्याओं जैसे पीरियड्स न आना या अनियमित होना, और असामान्य रक्तस्राव को नियंत्रित करने में मदद करती है। यह उन महिलाओं में भी दी जाती है जो हार्मोन रिप्लेसमेंट थेरेपी ले रही हैं और जिनका गर्भाशय अभी भी मौजूद है। यह दवा गर्भाशय की परत को मजबूत बनाती है और गर्भावस्था को बनाए रखने में सहायता करती है। इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर रात को सोने से पहले। इसे लेने के बाद नींद और चक्कर आ सकते हैं, इसलिए गाड़ी चलाने से बचें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, चक्कर आना, सिरदर्द, स्तनों में कोमलता, जी मिचलाना, पेट में गैस बनना और माहवारी में बदलाव शामिल हैं। ये आमतौर पर हल्के होते हैं और शरीर के सामान्य होने पर कम हो जाते हैं। कुछ महिलाओं को मूड में बदलाव या चिड़चिड़ापन भी महसूस हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे, होंठ या गले में सूजन, सांस लेने में तकलीफ, सीने में दर्द, पैर में दर्द या सूजन, आंखों या त्वचा का पीला पड़ना, या बहुत ज्यादा रक्तस्राव हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। टैबलेट को पानी के साथ पूरा निगलें, चबाएं या तोड़ें नहीं। इसे भोजन के साथ या रात को सोने से पहले लेने से चक्कर और जी मिचलाना कम हो सकता है। अपने आप दवा शुरू, बंद या डोज बदलें नहीं। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। अपनी सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों के बारे में डॉक्टर को जानकारी दें। इस दवा के साथ शराब न लें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। दवा को ठंडी, सूखी जगह पर, धूप से दूर, बच्चों की पहुंच से बाहर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 pregsure 200mg capsule Uses & Benefits

[{"condition":"Luteal phase support in assisted reproduction","description":"This medicine is used to support the lining of the uterus after fertility treatments such as IVF, helping to improve the chance of implantation and pregnancy.","evidence":"Well-established"},{"condition":"Threatened or recurrent miscarriage due to luteal phase defect","description":"This medicine may be prescribed to support early pregnancy when the body is not producing enough progesterone on its own.","evidence":"Established in selected cases"},{"condition":"Secondary amenorrhea","description":"This medicine can help restart menstrual periods in women whose periods have stopped due to low progesterone or hormonal imbalance.","evidence":"Well-established"},{"condition":"Abnormal uterine bleeding due to hormonal imbalance","description":"This medicine helps stabilize the uterine lining and reduce irregular or heavy bleeding caused by hormonal imbalance.","evidence":"Well-established"},{"condition":"Hormone replacement therapy in women with a uterus","description":"This medicine is used along with estrogen to protect the uterine lining in women going through menopause who still have a uterus.","evidence":"Well-established"},{"condition":"Luteal phase support in infertility","description":"This medicine is used to support the second half of the menstrual cycle in women undergoing fertility treatment.","evidence":"Established"}]

Off-label uses: [{"condition":"Preterm birth prevention","description":"This medicine is sometimes used off-label to help prevent premature birth in women at risk, but evidence is mixed and it is not a standard first-line treatment.","evidence":"Limited and conflicting"},{"condition":"Catamenial epilepsy","description":"This medicine has been studied off-label for seizures that worsen around menstrual periods, but it is not a routine treatment.","evidence":"Limited"},{"condition":"Menopausal hot flashes","description":"This medicine is occasionally used off-label to help with hot flashes, but it is not a first-choice treatment for this symptom.","evidence":"Limited"}]

Primary treatment for: Progesterone deficiency and related conditions

Also treats: Infertility, Recurrent miscarriage, Secondary amenorrhea, Abnormal uterine bleeding, Menopausal symptoms in women with a uterus

📋 Drug Information

Generic Name(s)Progesterone (Natural Micronized) (200mg)
Brand Namepregsure 200mg capsule
ManufacturerSerene Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassNatural Progesterone
Route of AdministrationOral
StorageStore this medicine at room temperature between 15°C and 30°C. Keep it in its original packaging, away from moisture, heat, and direct sunlight. Do not refrigerate unless your pharmacist has advised you to do so. Keep it out of reach of children and pets.
Shelf LifeThe shelf life of this medicine is usually 24 to 36 months from the date of manufacture, depending on the batch. Always check the expiry date on the pack before taking it. Do not use the medicine after the expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at bedtime to reduce daytime drowsiness and dizziness.
2
Take it with food, especially a meal containing some fat, to improve absorption and reduce stomach upset.
3
Do not drive or operate heavy machinery until you know how this medicine affects you.
4
Avoid alcohol completely while taking this medicine because it increases drowsiness and dizziness.
5
Keep a diary of your menstrual bleeding, symptoms, and side effects to discuss at your next appointment.
6
Do not stop this medicine suddenly, especially during pregnancy or fertility treatment, without talking to your doctor first.
7
Tell your doctor about all other medicines, especially antifungals, antibiotics, seizure medicines, and blood thinners.
8
Use reliable contraception if you are taking this medicine for a non-pregnancy reason and do not wish to conceive.
9
Report any unusual bleeding, severe headache, vision changes, leg pain, or breathing difficulty immediately.
10
Attend all follow-up visits so your doctor can monitor your response and adjust the dose if needed.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Irregular or absent menstrual periods
This medicine is commonly prescribed for menstrual problems caused by hormonal imbalance.
Likely Use
Abnormal uterine bleeding
This medicine can help stabilize the uterine lining and reduce irregular bleeding.
Likely Use
Need for luteal support in fertility treatment
This medicine is often used to support the uterine lining after fertility procedures.
Likely Use
Menopausal symptoms in women with a uterus
This medicine is used with estrogen to protect the uterine lining.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Common cold or cough
This medicine is not used to treat infections or cold symptoms.
Not Primary
Joint pain
This medicine is not a pain reliever for joint or muscle pain.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the gastrointestinal tract after oral administration. The micronized form improves absorption compared with non-micronized progesterone. Absorption can be increased when the tablet is taken with food, especially a fatty meal.
DistributionThis medicine is widely distributed in the body. It is highly bound to plasma proteins, mainly albumin and corticosteroid-binding globulin. It crosses the placenta and is also found in breast milk.
Protein BindingApproximately 96 to 99 percent bound to plasma proteins, mainly albumin and corticosteroid-binding globulin.
MetabolismThis medicine is extensively metabolized in the liver, mainly by cytochrome P450 enzymes, including CYP3A4. The main metabolites are pregnanediol and pregnanolone, which are later conjugated and excreted.
Half-LifeThe elimination half-life of this medicine is approximately 5 to 20 hours, depending on the individual and the formulation.
ExcretionThis medicine and its metabolites are mainly excreted in the urine as glucuronide and sulfate conjugates. A small amount is excreted in the bile and feces.
BioavailabilityThe oral bioavailability of this medicine is variable and is increased when taken with food. The micronized formulation improves absorption compared with non-micronized progesterone.
Onset of ActionThe onset of action depends on the indication. For luteal support, effects on the uterine lining may take several days. For sleep-related effects, drowsiness may occur within 1 to 3 hours after taking the dose.
Peak Plasma TimePeak plasma levels of this medicine are usually reached about 1 to 3 hours after oral administration, but this can vary between individuals and is affected by food.
Duration of ActionThe duration of action of this medicine depends on the dose and indication. For hormonal effects on the uterus, the effect lasts as long as the medicine is taken regularly. For sedation, the effect may last several hours.

How It Works

This medicine contains natural micronized progesterone, which is chemically identical to the progesterone produced by the ovaries and placenta. It works by binding to progesterone receptors in the nucleus of target cells, especially in the uterus, breast, and brain. Once bound, it changes the way certain genes are read, which helps prepare and maintain the uterine lining for pregnancy, supports the normal menstrual cycle, and balances the effects of estrogen. In the brain, it can have a mild calming effect, which explains why some women feel drowsy after taking it. Because it is micronized, the particles are very small, which helps the body absorb the hormone more effectively when taken by mouth.

Mechanism Steps

1
Absorption and entry into cells: After swallowing, this medicine is absorbed from the gut and travels through the bloodstream to target tissues such as the uterus, breast, and brain.
2
Binding to progesterone receptors: Inside target cells, this medicine binds to progesterone receptors in the nucleus, similar to the body's own progesterone.
3
Gene regulation: The medicine-receptor complex attaches to specific DNA regions and changes the activity of certain genes involved in the menstrual cycle and pregnancy.
4
Uterine lining changes: These gene changes transform the uterine lining into a supportive state for a fertilized egg and help maintain pregnancy.
5
Brain and other tissue effects: The medicine also acts on the brain and other tissues, which can cause mild drowsiness and help balance estrogen effects.

💡 How to Take pregsure 200mg capsule

Strength: This medicine is available as an oral tablet containing 200 mg of natural micronized progesterone.

1Read the label and follow your doctor's instructions exactly.
2Swallow the tablet whole with a glass of water.
3Take it with food or at bedtime to reduce dizziness and nausea.
4Do not crush, chew, or break the tablet unless your doctor or pharmacist says it is okay.
5If you miss a dose, follow the missed dose instructions.
6Do not take more than the prescribed dose.
7Keep a record of your doses and any side effects.
8Store the medicine properly and keep it away from children.

Dosage Information

Adult DosageThe dose of this medicine depends on the condition being treated, your age, your medical history, and how you respond to treatment. For luteal support in fertility treatment, a common dose is 200 mg to 400 mg per day, often taken as one or more doses. For hormone replacement therapy, the dose is usually 200 mg at bedtime for 12 to 14 days each month. For other conditions, your doctor will decide the right dose for you. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose on your own.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly women can usually take this medicine at the same doses as younger adults, but they may be more sensitive to side effects such as drowsiness and dizziness. Start with the lowest effective dose and monitor closely. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Renal ImpairmentThis medicine is mainly excreted by the kidneys. Women with mild to moderate kidney disease usually do not need a dose change, but those with severe kidney disease should be monitored closely. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Hepatic ImpairmentThis medicine is processed by the liver. Women with mild to moderate liver disease may need a lower dose or less frequent dosing. This medicine should not be used in women with severe liver disease. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Maximum Daily DoseThe maximum daily dose of this medicine depends on the condition being treated and should be determined by your doctor. In general, doses above 400 mg per day are not commonly used without specialist supervision. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals or at bedtime
Food improves absorption and reduces dizziness and nausea.
Fatty meals
Can take with a meal containing some fat
Fat increases the absorption of this medicine.
Grapefruit and grapefruit juice
Avoid or limit
Grapefruit can increase the levels of this medicine in the blood.
Alcohol
Avoid
Alcohol increases drowsiness and dizziness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with your regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.
📌 You are unsure what to do
→ Contact your doctor or pharmacist for advice.
💡 Do not guess or take extra doses.

⚠️ Side Effects of pregsure 200mg capsule

✅ Common Side Effects

Drowsiness or sleepiness (Common (more than 10%))
Take the dose at bedtime if your doctor agrees. Avoid driving or operating machinery until you know how it affects you.
Dizziness (Common (5 to 10%))
Stand up slowly and avoid sudden movements. If dizziness is severe or persistent, contact your doctor.
Headache (Common (5 to 10%))
Rest, stay hydrated, and use a mild pain reliever if your doctor approves. Seek care if the headache is severe or unusual.
Breast tenderness (Common (5 to 10%))
Wear a supportive bra and apply a warm compress if needed. Tell your doctor if it persists or worsens.
Nausea (Common (5 to 10%))
Take the tablet with food or at bedtime to reduce nausea. If vomiting occurs, contact your doctor.
Bloating or fluid retention (Common (5 to 10%))
Reduce salt intake and stay active. Report sudden weight gain or swelling to your doctor.
Mood changes or irritability (Uncommon (1 to 5%))
Talk to your doctor if mood changes are troubling or affect your daily life.
Irregular vaginal bleeding or spotting (Common (5 to 10%))
Keep a record of bleeding and inform your doctor. Seek urgent care if bleeding is heavy.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (less than 0.1%))
Seek emergency medical help immediately if you have swelling of the face, lips, tongue, or throat, difficulty breathing, or a widespread rash.
Blood clots (deep vein thrombosis or pulmonary embolism) (Rare (less than 0.1%))
Go to the emergency room if you have calf pain or swelling, chest pain, sudden shortness of breath, or coughing up blood.
Severe liver problems (Rare (less than 0.1%))
Seek medical care if you notice yellowing of the eyes or skin, dark urine, severe abdominal pain, or persistent nausea and vomiting.
Stroke or heart attack (Very rare (less than 0.01%))
Call emergency services if you have sudden weakness or numbness on one side, trouble speaking, severe chest pain, or sudden vision loss.
Severe depression or mood disturbance (Rare (less than 0.1%))
Contact your doctor or a mental health professional immediately if you feel severely depressed or have thoughts of harming yourself.

⚠️ Rare Side Effects

Jaundice
Seek medical attention if your skin or eyes turn yellow.
Seizures
Call emergency services if you have a seizure.
Severe skin reactions such as Stevens-Johnson syndrome
Go to the emergency room if you develop a painful rash with blisters or peeling skin.
Pancreatitis
Seek urgent care for severe upper abdominal pain that radiates to the back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Rifampicin Major
Warfarin Major
Diazepam Moderate
Levothyroxine Moderate
Amlodipine Moderate
Grapefruit juice Minor
Paracetamol Minor
St. John's wort Major
Carbamazepine Major

🚨 Major Interactions

  • Strong CYP3A4 inhibitors such as ketoconazole, itraconazole, clarithromycin, and ritonavir
  • Strong CYP3A4 inducers such as rifampicin, carbamazepine, phenytoin, and St. John's wort
  • Warfarin and other anticoagulants

⚡ Moderate Interactions

  • Benzodiazepines and other sedatives
  • Antihypertensive medicines
  • Thyroid hormone (levothyroxine)

🍷 Alcohol Interaction

Alcohol can increase the drowsiness and dizziness caused by this medicine. It is best to avoid alcohol while taking this medicine, especially if you need to drive or operate machinery. If you choose to drink, do so only occasionally and in small amounts, and never right after taking your dose.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to progesterone or any ingredient in this medicine","Unexplained vaginal bleeding that has not been evaluated by a doctor","Known or suspected breast cancer","Known or suspected progesterone-sensitive tumors","Active liver disease or severe liver problems","History of blood clots in the legs, lungs, or brain","Known or suspected pregnancy loss with retained products of conception","Severe kidney disease without medical supervision"]

⚠️ Warnings & Precautions

["This medicine can cause drowsiness and dizziness. Avoid driving or operating heavy machinery until you know how it affects you.","Take this medicine at bedtime if your doctor advises, to reduce daytime drowsiness.","Inform your doctor if you have a history of depression, liver disease, kidney disease, heart disease, or blood clots.","Do not use this medicine if you are allergic to progesterone or any of its ingredients.","Tell your doctor about all other medicines, supplements, and herbal products you are taking.","Avoid alcohol while taking this medicine because it can increase drowsiness.","Use reliable contraception if you are taking this medicine for a non-pregnancy reason and do not wish to conceive.","Keep all follow-up appointments and report any unusual symptoms promptly."]

🤱 Lactation Safety

This medicine passes into breast milk in small amounts. It is generally considered compatible with breastfeeding when prescribed by a doctor, but the benefits and risks should be discussed with your clinician. Monitor the baby for any unusual drowsiness or poor feeding and report these to your doctor.

💊 Overdose Management

If you or someone else takes too much of this medicine, seek medical help immediately. Symptoms of overdose may include severe drowsiness, dizziness, nausea, vomiting, and in women, withdrawal bleeding. Treatment is supportive and based on symptoms. Do not try to vomit unless a healthcare professional tells you to do so. Carry the medicine packaging with you to the hospital so the medical team knows exactly what was taken.

⏰ Missed Dose

If you miss a dose of this medicine, take it as soon as you remember if it is less than half the time until your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, contact your doctor or pharmacist.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Swallow the tablet whole with water; do not crush, chew, or break it unless your doctor or pharmacist has advised you to do so. Taking this medicine with food, especially at bedtime, can reduce dizziness and drowsiness. Do not start, stop, or change the dose on your own. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding, because the dose and suitability depend on your situation. Tell your doctor about all other medicines, including blood thinners, antifungals, antibiotics, seizure medicines, and herbal products, as some can interact with this medicine. Avoid alcohol while taking this medicine because it can increase drowsiness and dizziness. Use reliable contraception if you are taking this medicine for a non-pregnancy reason and do not wish to conceive. Keep all follow-up appointments and report any unusual bleeding, severe headache, vision changes, leg pain, or breathing difficulty immediately. Store this medicine in its original packaging, away from moisture, heat, and direct sunlight, and keep it out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Women above 65 years of age may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. They may also have a higher risk of blood clots and liver problems. The dose should be individualized by a qualified clinician, and regular monitoring is recommended. Falls and accidents related to dizziness should be avoided by taking the medicine at bedtime and getting up slowly.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, talk to your doctor before starting or continuing this medicine. This medicine is often used to support early pregnancy in women who need extra progesterone. Your doctor will decide the right dose and duration based on your fertility treatment plan or history of miscarriage. Do not start or stop this medicine on your own while trying to conceive.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, tell your surgeon and anesthesiologist that you are taking this medicine. This medicine may increase the risk of blood clots, so your doctor may advise you to stop it for a short period before surgery or take extra precautions. Do not stop the medicine on your own; follow your doctor's instructions carefully.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. There is no major interaction with common dental anesthetics, but your dentist should know about all medicines you take. If you are taking blood thinners along with this medicine, tell your dentist because of the increased risk of bleeding.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight through balanced diet and regular physical activity.
🥗
Avoid alcohol and smoking, as both can worsen hormonal imbalance and increase side effects.
😴
Get regular sleep and try to go to bed at the same time each night.
💧
Manage stress with relaxation techniques such as deep breathing, yoga, or meditation.
🧘
Stay physically active with low-impact exercises like walking, swimming, or cycling.
🌞
Eat a balanced diet rich in fruits, vegetables, whole grains, and lean proteins.
🚭
Keep a symptom diary to track your menstrual cycle, mood, and any side effects.
🥑
Attend all follow-up appointments and health check-ups.

🏋️ Exercise Considerations

This medicine can cause drowsiness and dizziness, especially in the first few days of treatment. Avoid heavy lifting, high-intensity workouts, or activities that require balance until you know how the medicine affects you. If you feel dizzy or weak during exercise, stop immediately and rest. Light to moderate exercise such as walking or stretching is usually safe and can help with overall well-being.

🥗 Diet Recommendations

Include plenty of fruits, vegetables, and whole grains in your diet.
Choose lean proteins such as fish, chicken, beans, and lentils.
Limit processed foods, sugary drinks, and excessive salt.
Include healthy fats such as olive oil, nuts, and seeds in moderation.
Stay well hydrated by drinking plenty of water throughout the day.
Avoid grapefruit and grapefruit juice while taking this medicine.
Limit caffeine if you notice increased dizziness or sleep problems.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, which may affect your ability to drive, operate machinery, or perform tasks that require concentration. It is best to take the dose at bedtime so that the sedative effect wears off by morning. If you still feel drowsy during the day, avoid driving and inform your employer if your work involves operating heavy equipment. Most women can continue their normal daily activities with some adjustments.

🛑 When to Stop This Medicine

Do not stop taking this medicine on your own. Your doctor will decide when it is safe to stop based on your condition and response to treatment. If you experience serious side effects such as severe allergic reactions, blood clots, liver problems, or severe mood changes, seek medical help immediately and follow your doctor's advice about stopping the medicine. If you are pregnant or undergoing fertility treatment, stopping suddenly can be harmful, so always consult your doctor first.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when taken under medical supervision. However, prolonged use may increase the risk of blood clots, liver problems, and mood changes in some women. Regular follow-up visits are important so your doctor can monitor your response and check for any side effects. Your doctor may order blood tests to check liver function and other parameters if you take this medicine for a long time. Do not continue this medicine for longer than prescribed without a review.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dydrogesterone

A synthetic progestin that can be used for similar conditions, often with less sedation.

Evidence: Well-established
Medroxyprogesterone acetate

A synthetic progestin used for menstrual problems and hormone replacement therapy.

Evidence: Well-established
Vaginal progesterone preparations

Progesterone given vaginally may be an option for luteal support with different side effect profiles.

Evidence: Well-established
Lifestyle and dietary changes

Weight management, regular exercise, and a balanced diet can help support hormonal balance.

Evidence: Supportive

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive routine vaccinations while taking this medicine unless your doctor advises otherwise. If you are pregnant, discuss the timing of any vaccines with your doctor.

📦 Storage Guide

✅ DO

Store at room temperature between 15°C and 30°C.

❌ DON'T

Do not refrigerate unless your pharmacist has advised you to do so.

✅ DO

Keep the medicine in its original container with the label intact.

❌ DON'T

Do not transfer the tablets to an unmarked container.

✅ DO

Keep the medicine away from direct sunlight and moisture.

❌ DON'T

Do not store it in the bathroom cabinet or near a sink.

✅ DO

Keep the medicine out of reach of children and pets.

❌ DON'T

Do not leave the medicine where children can see or reach it.

✅ DO

Check the expiry date before taking the medicine.

❌ DON'T

Do not use the medicine after the expiry date.

✈️ Traveling with This Medicine

When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Keep a copy of your prescription or a letter from your doctor in case you need to show it at customs or security. Store the medicine in your hand luggage, away from direct sunlight and extreme heat. If you are crossing time zones, ask your doctor how to adjust the timing of your doses so that you maintain steady hormone levels. Do not leave the medicine in a hot car or checked luggage. If you are travelling for a long period, carry enough medicine for the entire trip and a little extra in case of delays.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman undergoing IVF treatment
She was prescribed this medicine to support the lining of her uterus after embryo transfer. She took it at bedtime as advised and noticed mild drowsiness in the first few days, which improved after a week. She kept all her follow-up appointments and avoided alcohol. Her pregnancy test was positive, and she continued the medicine under her doctor's supervision.
💡 Lesson: Taking this medicine at bedtime and following the prescribed schedule helps with tolerability and supports the best chance of success during fertility treatment.
👤 A 48-year-old woman with irregular periods and heavy bleeding
She was prescribed this medicine for abnormal uterine bleeding caused by hormonal imbalance. She took it for 12 days each month as directed. Her bleeding became more regular within two cycles, and her energy levels improved. She reported mild breast tenderness, which her doctor said was a common side effect and would settle with time.
💡 Lesson: This medicine can help regulate the menstrual cycle when taken exactly as prescribed, and mild side effects often improve with continued use.
👤 A 55-year-old woman on hormone replacement therapy
She was started on estrogen therapy after menopause and was given this medicine to protect her uterine lining. She took it at night and found it helped her sleep better. She had regular check-ups, and her doctor monitored her liver function and blood pressure. She remained well on treatment.
💡 Lesson: When used with estrogen in women who still have a uterus, this medicine helps protect the uterine lining and should be taken exactly as prescribed with regular monitoring.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The time it takes to work depends on the condition being treated. For menstrual problems, you may notice changes within one or two cycles. For luteal support in fertility treatment, the effect on the uterine lining develops over several days. For sleep-related effects, drowsiness may occur within a few hours of taking the dose.

Q: Can I take this medicine with food?

A: Yes, you can take this medicine with food. Taking it with a meal, especially one that contains some fat, improves absorption and reduces dizziness and nausea. Many women find it helpful to take it at bedtime.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember if it is less than half the time until your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.

Q: Can I drink alcohol while taking this medicine?

A: It is best to avoid alcohol while taking this medicine because it can increase drowsiness and dizziness. If you choose to drink, do so only occasionally and in small amounts, and never right after taking your dose.

Q: Is this medicine safe during pregnancy?

A: This medicine is used to support pregnancy in specific situations and is generally considered acceptable when prescribed by a doctor. However, the decision to use it during pregnancy should be made by a qualified clinician based on your individual condition and needs.

Q: Can I stop taking this medicine suddenly?

A: No, do not stop taking this medicine suddenly, especially during pregnancy or fertility treatment, without talking to your doctor first. Stopping suddenly can cause hormonal changes or bleeding. Your doctor will advise you on how to stop safely if needed.

Q: Does this medicine interact with other medicines?

A: Yes, this medicine can interact with some other medicines, including antifungals, antibiotics, seizure medicines, blood thinners, and herbal products such as St. John's wort. Always tell your doctor about all medicines and supplements you are taking.

Q: Will this medicine cause weight gain?

A: Some women may notice mild fluid retention or bloating, but not everyone gains weight. A healthy diet and regular physical activity can help manage this. If you notice sudden weight gain or swelling, contact your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver or kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Will this medicine cause weight gain?
  • Can I take this medicine during pregnancy?
  • Is it safe to breastfeed while taking this medicine?
  • How long does it take to work?

🔄 Substitutes for pregsure 200mg capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a contraceptive pill.
    Fact: This medicine is not a contraceptive. It is used for hormonal support and other conditions. If you need contraception, talk to your doctor about suitable options.
  • Myth: This medicine can be taken at any time of day without any effect.
    Fact: This medicine can cause drowsiness, so it is often taken at bedtime. Taking it at the same time each day helps keep hormone levels steady.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription medicine. It should only be taken under the supervision of a qualified doctor.
  • Myth: This medicine will cause weight gain in everyone.
    Fact: Some women may notice mild fluid retention or bloating, but not everyone gains weight. A healthy diet and regular activity can help.
  • Myth: This medicine can be stopped suddenly without any problem.
    Fact: Stopping this medicine suddenly can cause hormonal changes or bleeding. Always talk to your doctor before stopping.

🔄 Alternative Options

Generic Alternatives

  • Natural micronized progesterone 200 mg tablet

Brand Alternatives

  • Endogest 200 SR Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (natural micronized progesterone 200 mg)","class":"Natural progestin","route":"Oral","common_uses":"Luteal support, menstrual problems, hormone replacement therapy","sedation":"Common","note":"Identical to the body's own progesterone."},{"medicine":"Dydrogesterone 10 mg","class":"Synthetic progestin","route":"Oral","common_uses":"Menstrual problems, luteal support, threatened miscarriage","sedation":"Uncommon","note":"Different chemical structure from natural progesterone."},{"medicine":"Medroxyprogesterone acetate 10 mg","class":"Synthetic progestin","route":"Oral","common_uses":"Menstrual problems, hormone replacement therapy","sedation":"Uncommon","note":"Not identical to natural progesterone."}]

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