alpha num 80mg/480mg tablet - Uses, Price, Side Effects & Substitutes
What is alpha num 80mg/480mg tablet used for?
Alpha Num 80mg/480mg Tablet (Arteether + Lumefantrine) is used to treat ANTI MALARIALS. It contains Arteether (80mg) + Lumefantrine (480mg), which Arteether: produces free radicals that damage parasite membranes; Lumefantrine: . Always consult your doctor before use. Take as prescribed.
- Generic Name: Arteether + Lumefantrine
- Manufacturer: Plenum Biotech
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ alpha num 80mg/480mg tablet Uses & Benefits
Uncomplicated Plasmodium falciparum malaria
Off-label uses: Treatment of other Plasmodium species
๐ Drug Information
| Generic Name(s) | Arteether + Lumefantrine |
| Brand Name | Alpha Num 80mg/480mg Tablet |
| Manufacturer | Plenum Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI MALARIALS |
| Action Class | Antimalarial |
| Route of Administration | Oral |
| Storage | Store at 25ยฐC (77ยฐF); protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Arteether: produces free radicals that damage parasite membranes; Lumefantrine: inhibits heme polymerization
Mechanism Steps
๐ก How to Take alpha num 80mg/480mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of alpha num 80mg/480mg tablet
โ Common Side Effects
- Headache
- Nausea
- Vomiting
- Abdominal pain
- Diarrhea
๐จ Serious Side Effects
- QT prolongation
- Severe allergic reactions
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Neurotoxicity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased arteether/lumefantrine levels |
| Rifampin | Major | Decreased arteether/lumefantrine levels |
| Warfarin | Major | Increased bleeding risk |
๐จ Major Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
- Anticoagulants
โก Moderate Interactions
- Anticonvulsants
- Antiretrovirals
- Macrolide antibiotics
โน๏ธ Minor Interactions
- Antacids
- Corticosteroids
๐ฝ๏ธ Food Interactions
Fatty food increases absorption of Lumefantrine, Grapefruit juice may increase levels
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to artemisinin derivatives or lumefantrine; severe hepatic impairment
๐ Monitoring Parameters
Parasitemia, ECG, liver function tests
๐คฑ Lactation Safety
Excreted in breast milk; caution advised
๐ Overdose Management
Symptomatic and supportive care; monitor ECG
โฐ Missed Dose
Take as soon as remembered; do not double dose