allerpar tablet - Calcium Gluconate (500mg) + Chlorpheniramine Maleate (4mg) medicine

Allerpar Tablet: Complete Guide To Uses, Side Effects, And Safety

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🏭 Paripurna Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 29, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for individual components; limited for combination.
Reviewed by
SaathiMed Expert Panel | Oct 29, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe drowsiness or confusion
  • Irregular heartbeat or palpitations
  • Seizures
  • Severe abdominal pain or vomiting
  • Signs of hypercalcemia: increased urination, excessive thirst, nausea
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is allerpar tablet used for?

This medicine is a combination of Calcium Gluconate and Chlorpheniramine Maleate used to treat allergic symptoms and calcium deficiency. It works by blocking histamine and supplementing calcium.

  • Generic Name: Calcium Gluconate (500mg) + Chlorpheniramine Maleate (4mg)
  • Manufacturer: Paripurna Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 allerpar tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी जैसे नाक बहना, छींक आना, खुजली, और त्वचा पर चकत्ते के इलाज में उपयोग की जाती है। यह कैल्शियम की कमी को भी पूरा करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुँह सूखना, चक्कर आना, और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, हृदय गति अनियमितता, या कैल्शियम का स्तर बढ़ना हो सकता है।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब न पिएं। गाड़ी चलाने या मशीन चलाने से बचें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 allerpar tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itching, and watery eyes associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Urticaria","description":"Reduces itching and hives by blocking histamine release.","evidence":"Well-established"},{"condition":"Calcium supplementation","description":"Provides calcium to treat or prevent calcium deficiency, especially in conditions like hypocalcemia or osteoporosis.","evidence":"Well-established"},{"condition":"Allergic skin conditions","description":"Helps alleviate itching and rash due to various allergic skin disorders.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Insomnia","description":"Sometimes used off-label for its sedative effects to promote sleep, but not recommended due to side effect profile.","evidence":"Limited"},{"condition":"Motion sickness","description":"Chlorpheniramine may help prevent motion sickness, but not a primary indication.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Urticaria, Calcium deficiency, Allergic skin conditions

📋 Drug Information

Generic Name(s)Calcium Gluconate (500mg) + Chlorpheniramine Maleate (4mg)
Brand Nameallerpar tablet
ManufacturerParipurna Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15-30°C (59-86°F). Protect from light and moisture. Keep in original container.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not consume alcohol while taking this medicine as it increases drowsiness.
4
Inform your doctor if you have glaucoma, prostate enlargement, or kidney disease.
5
Do not take this medicine for longer than prescribed without consulting your doctor.
6
If you experience persistent drowsiness or dizziness, contact your doctor.
7
Keep all follow-up appointments to monitor calcium levels if on long-term therapy.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Sneezing and runny nose
This medicine is commonly prescribed for allergic rhinitis.
Likely Use
✅
Itchy skin rash
Used for urticaria and allergic skin conditions.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Muscle cramps due to calcium deficiency
Calcium gluconate component helps treat calcium deficiency.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine is well absorbed from the gastrointestinal tract after oral administration. Calcium gluconate is also absorbed, but its absorption depends on vitamin D status and other factors. Not established from the available information for specific pharmacokinetic parameters of this combination.
DistributionChlorpheniramine is widely distributed in body tissues and crosses the blood-brain barrier. Calcium is distributed primarily to bones and teeth, with some in extracellular fluids. Not established from the available information for specific volume of distribution.
Protein BindingChlorpheniramine is approximately 70% bound to plasma proteins. Calcium is not significantly protein-bound. Not established from the available information for exact values.
MetabolismChlorpheniramine is metabolized in the liver by cytochrome P450 enzymes, primarily CYP2D6. Calcium is not metabolized. Not established from the available information for specific metabolic pathways.
Half-LifeThe elimination half-life of chlorpheniramine is approximately 12-15 hours in adults. Calcium is eliminated via renal excretion and other routes. Not established from the available information for the combination.
ExcretionChlorpheniramine and its metabolites are excreted primarily in urine. Calcium is excreted mainly in feces and urine. Not established from the available information for specific excretion rates.
BioavailabilityChlorpheniramine has a bioavailability of about 25-50% due to first-pass metabolism. Calcium bioavailability varies. Not established from the available information for this specific product.
Onset of ActionChlorpheniramine onset of action is typically 30-60 minutes after oral administration. Calcium effects are not immediate. Not established from the available information for the combination.
Peak Plasma TimePeak plasma concentration of chlorpheniramine is reached in about 2-6 hours. Calcium peak is variable. Not established from the available information for the combination.
Duration of ActionChlorpheniramine duration of action is about 4-6 hours, but sedative effects may last longer. Calcium effects are long-term. Not established from the available information for the combination.

How It Works

This medicine combines two active ingredients. Chlorpheniramine Maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, preventing histamine-mediated allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation. Calcium Gluconate provides calcium ions, which are essential for various physiological processes including bone mineralization, neuromuscular transmission, and blood coagulation. The combination does not have a synergistic mechanism but addresses allergic symptoms and calcium supplementation concurrently.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine binds to H1 receptors on effector cells, preventing histamine from triggering allergic symptoms.
2
Calcium ion supplementation: Calcium gluconate dissociates to release calcium ions, which are utilized in various physiological functions.
3
Anticholinergic effects: Chlorpheniramine also blocks muscarinic receptors, leading to dry mouth, constipation, and urinary retention.
4
Central nervous system depression: Chlorpheniramine crosses the blood-brain barrier and causes sedation by blocking histamine in the CNS.

💡 How to Take allerpar tablet

Strength: Tablet containing Calcium Gluconate 500 mg and Chlorpheniramine Maleate 4 mg.

1Take this medicine orally with a glass of water.
2It can be taken with or without food, but taking with food may reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at the same time each day to maintain consistent levels.
5Do not exceed the prescribed dose.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally once or twice daily, or as directed by your physician. The dose may be adjusted based on the condition being treated and your response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of chlorpheniramine, especially drowsiness, confusion, and anticholinergic effects. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Calcium excretion may be reduced, increasing risk of hypercalcemia. Chlorpheniramine may accumulate. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Chlorpheniramine is metabolized in the liver; dose adjustment may be needed. Consult a doctor.
Maximum Daily DoseThe maximum recommended daily dose is not established from available information. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases sedation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of allerpar tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult doctor.
Dry mouth (Common (5-10%))
Sip water, chew sugarless gum. Consult if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid alcohol.
Nausea (Common (5-10%))
Take with food. Consult if persistent.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, difficulty breathing.
Hypercalcemia (Rare (<0.1%))
Report symptoms like nausea, vomiting, increased urination, confusion. Seek medical help.
Blood dyscrasias (Rare (<0.1%))
Report unusual bleeding, bruising, or fatigue. Consult doctor.
Seizures (Rare (<0.1%))
Seek emergency medical care if seizures occur.

⚠️ Rare Side Effects

Photosensitivity
Use sunscreen, avoid prolonged sun exposure.
Hepatotoxicity
Report yellowing of skin or eyes, dark urine. Seek medical attention.
Nephrolithiasis
Report flank pain, blood in urine. Consult doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Alcohol Major
Thiazide diuretics Major
Anticholinergics Moderate
Fluoroquinolones Moderate
Tetracyclines Moderate
Corticosteroids Minor
Loop diuretics Minor

🚨 Major Interactions

  • MAO inhibitors
  • CNS depressants (alcohol, benzodiazepines, opioids)
  • Thiazide diuretics

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • Fluoroquinolones
  • Tetracyclines

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine as it can potentiate the sedative effects of chlorpheniramine, leading to increased drowsiness, dizziness, and impaired coordination. This can affect your ability to drive or operate machinery and may increase the risk of accidents.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chlorpheniramine, calcium gluconate, or any component","Narrow-angle glaucoma","Urinary retention","Severe liver disease","Severe kidney disease","Hypercalcemia","Concurrent use with MAO inhibitors"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in elderly due to increased risk of confusion and falls.","Use with caution in children; paradoxical excitation may occur.","Do not use for prolonged periods without medical supervision.","Inform doctor if you have asthma, glaucoma, or prostate enlargement.","Calcium supplements may increase risk of kidney stones.","Do not exceed recommended dose."]

🤱 Lactation Safety

Chlorpheniramine is excreted in breast milk and may cause drowsiness in the infant. Calcium gluconate is safe. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, seizures, coma, hypercalcemia, or cardiac arrhythmias. Seek immediate medical attention. Treatment is supportive and symptomatic. Gastric lavage may be considered if recent ingestion. Monitor vital signs, serum calcium, and electrolytes. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid alcohol and other central nervous system depressants as they can enhance drowsiness. Inform your doctor if you have glaucoma, prostate enlargement, urinary retention, asthma, or kidney/liver disease. Do not use this medicine for prolonged periods without medical supervision. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use. Do not drive or operate heavy machinery until you know how this medicine affects you. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more susceptible to the anticholinergic and sedative effects of chlorpheniramine, which can lead to confusion, falls, and urinary retention. Use with caution and consider lower doses. Monitor renal function and calcium levels regularly.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Chlorpheniramine is generally considered safe but should be used only if clearly needed. Calcium supplementation is important for fetal development, but dose should be individualized.

🏥 Post-Surgery Considerations

After surgery, inform your surgeon and anesthesiologist about this medicine. Chlorpheniramine may interact with anesthetic agents and increase sedation. Calcium levels may need monitoring.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it can cause dry mouth and may interact with local anesthetics or sedatives used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints and bones.
🥗
Engage in regular low-impact exercise like walking or swimming.
😴
Practice good posture to support bone health.
💧
Include calcium-rich foods in your diet such as dairy, leafy greens, and fortified cereals.
🧘
Get adequate sleep to support overall health.
🌞
Avoid smoking and limit alcohol consumption.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness, which can affect your coordination. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you experience dizziness, rest and avoid physical exertion.

🥗 Diet Recommendations

Include calcium-rich foods like milk, yogurt, and cheese.
Ensure adequate vitamin D intake for calcium absorption.
Stay well hydrated to prevent kidney stones.
Limit caffeine and alcohol as they can affect calcium absorption and increase drowsiness.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to perform tasks requiring alertness, such as driving or operating machinery. It is advisable to take it at bedtime if once-daily dosing, to minimize daytime sedation. Inform your employer if your job involves safety-sensitive tasks.

🛑 When to Stop This Medicine

Do not stop taking this medicine abruptly without consulting your doctor. If you experience severe side effects or no improvement in symptoms, contact your doctor. Your doctor may adjust the dose or switch to an alternative.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance to the sedative effects of chlorpheniramine, and prolonged calcium supplementation may increase the risk of hypercalcemia and kidney stones. Regular monitoring of serum calcium and renal function is advised. Do not use for extended periods without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Identifying and avoiding allergens can reduce the need for medication.

Evidence: Well-established
Nasal saline irrigation

Helps relieve nasal congestion and allergy symptoms.

Evidence: Moderate
Calcium-rich diet

Dietary calcium can help maintain calcium levels without supplements.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines. Keep a list of your medications with you at all times.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She was prescribed this medicine for her allergic rhinitis. She experienced significant relief from sneezing and runny nose within a few days. She noted that taking it at bedtime helped with drowsiness and didn't interfere with her work.
💡 Lesson: Taking sedating antihistamines at bedtime can minimize daytime drowsiness.
👤 A 60-year-old man with calcium deficiency and mild allergies
He was prescribed this medicine to address both his calcium deficiency and allergic symptoms. He was advised to take it with food. After a month, his calcium levels improved, and his allergy symptoms were controlled. He was monitored for kidney function.
💡 Lesson: Regular monitoring is important when taking calcium supplements long-term.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Chlorpheniramine starts working within 30-60 minutes, providing relief from allergic symptoms. Calcium supplementation effects take longer to manifest.

Q: Can I take this medicine with other antihistamines?

A: No, taking multiple antihistamines can increase side effects. Consult your doctor before combining.

Q: Is it safe to take during pregnancy?

A: Consult your doctor. Chlorpheniramine is category B, but individual assessment is needed.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for the next dose, skip it. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for allerpar tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for any allergy without prescription.
    Fact: It is a prescription medicine and should only be taken under medical supervision.
  • Myth: It is safe to drive after taking this medicine.
    Fact: It can cause drowsiness; avoid driving until you know how it affects you.
  • Myth: More calcium is always better.
    Fact: Excess calcium can lead to hypercalcemia and kidney stones.

🔄 Alternative Options

Generic Alternatives

  • Calcium Gluconate + Chlorpheniramine Maleate combination tablets

Brand Alternatives

  • Allerpar Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Allerpar Tablet","composition":"Calcium Gluconate 500mg + Chlorpheniramine Maleate 4mg","uses":"Allergic rhinitis, urticaria, calcium deficiency","sedation":"High"},{"medicine":"Cetirizine","composition":"Cetirizine 10mg","uses":"Allergic rhinitis, urticaria","sedation":"Low"},{"medicine":"Loratadine","composition":"Loratadine 10mg","uses":"Allergic rhinitis, urticaria","sedation":"Low"}]

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