allercalcin tablet - Calcium Gluconate (500mg) + Chlorpheniramine Maleate (4mg) medicine

Allercalcin Tablet: Complete Guide To Uses, Side Effects, And Safety

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🏭 Retort Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 29, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Oct 29, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe drowsiness or difficulty staying awake
  • Confusion or hallucinations
  • Irregular heartbeat or palpitations
  • Swelling of face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Excessive thirst or frequent urination
  • Yellowing of skin or eyes
  • Severe abdominal pain or vomiting

If experiencing severe symptoms, call emergency services immediately.

What is allercalcin tablet used for?

This medicine is a combination of Calcium Gluconate and Chlorpheniramine Maleate used to treat allergic symptoms and calcium deficiency. It works by blocking histamine and supplementing calcium. It may cause drowsiness, so avoid driving. Always take as prescribed by your doctor.

  • Generic Name: Calcium Gluconate + Chlorpheniramine Maleate
  • Manufacturer: Retort Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 allercalcin tablet के बारे में (Hindi Summary)

उपयोग: यह दवा कैल्शियम ग्लूकोनेट और क्लोरफेनिरामाइन मेलिएट का संयोजन है। इसका उपयोग एलर्जी के लक्षणों जैसे छींक, नाक बहना, खुजली और आंखों में पानी आना को कम करने के लिए किया जाता है। यह कैल्शियम की कमी को भी पूरा करती है। यह दवा नींद और सुस्ती ला सकती है, इसलिए वाहन चलाने से बचें। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना, थकान और हल्का पेट दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज धड़कन, भ्रम, या कैल्शियम का स्तर बढ़ने के लक्षण जैसे अत्यधिक प्यास, बार-बार पेशाब आना और मांसपेशियों में कमजोरी शामिल हो सकते हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। इस दवा को लेने के बाद वाहन चलाने या मशीनरी चलाने से बचें क्योंकि इससे नींद आ सकती है। शराब और अन्य नींद लाने वाली दवाओं से बचें। यदि आपको गुर्दे की बीमारी, हृदय रोग, ग्लूकोमा या पेशाब में कठिनाई है तो डॉक्टर को बताएं। बिना डॉक्टर की सलाह के कैल्शियम सप्लीमेंट न लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 allercalcin tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itching, and watery eyes associated with seasonal or perennial allergies.","evidence":"Well-established for chlorpheniramine component"},{"condition":"Calcium deficiency","description":"Provides supplemental calcium for individuals with inadequate dietary intake or increased requirements.","evidence":"Well-established for calcium gluconate component"},{"condition":"Urticaria","description":"Helps reduce itching and hives due to allergic skin reactions.","evidence":"Well-established for chlorpheniramine component"},{"condition":"Angioedema (mild)","description":"May be used as adjunctive therapy for mild allergic inflammation" class="semantic-link" title="Medicines for swelling">swelling, but not for severe cases.","evidence":"Limited"}]

Off-label uses: [{"condition":"Insomnia","description":"Sometimes used off-label for its sedative effects, but not recommended due to potential side effects.","evidence":"Limited"},{"condition":"Motion sickness","description":"Chlorpheniramine may help prevent motion sickness, but this combination is not specifically approved for this use.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Calcium deficiency, Urticaria, Angioedema (mild)

📋 Drug Information

Generic Name(s)Calcium Gluconate + Chlorpheniramine Maleate
Brand NameAllercalcin Tablet
ManufacturerRetort Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action ClassAntihistamine with Calcium Supplement
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not drink alcohol while taking this medicine as it can increase drowsiness.
4
Inform your doctor if you have kidney disease, glaucoma, or difficulty urinating.
5
Do not take additional calcium supplements without consulting your doctor.
6
If you miss a dose, take it as soon as you remember, but do not double the dose.
7
Consult your doctor if symptoms persist beyond 7 days or worsen.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Sneezing and runny nose
This medicine is commonly prescribed for allergic rhinitis.
Likely Use
✅
Itchy skin or hives
Chlorpheniramine helps relieve itching.
Likely Use
✅
Calcium deficiency
Calcium gluconate provides supplemental calcium.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Severe allergic reaction (anaphylaxis)
This medicine is not for emergency treatment of anaphylaxis.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCalcium is absorbed in the small intestine via active vitamin D-dependent transport and passive diffusion. Chlorpheniramine is well absorbed from the gastrointestinal tract after oral administration.
DistributionCalcium is distributed primarily to bones and teeth, with some in extracellular fluids. Chlorpheniramine is widely distributed in body tissues and crosses the blood-brain barrier, which explains its sedative effects.
Protein BindingChlorpheniramine is approximately 70% bound to plasma proteins. Calcium is not significantly protein-bound.
MetabolismChlorpheniramine is metabolized in the liver, primarily by CYP2D6 and CYP3A4 enzymes. Calcium is not metabolized.
Half-LifeThe elimination half-life of chlorpheniramine is approximately 12 to 43 hours. Calcium is eliminated via renal excretion and fecal loss.
ExcretionChlorpheniramine and its metabolites are excreted mainly in urine. Calcium is excreted primarily in urine and feces.
BioavailabilityChlorpheniramine has a bioavailability of approximately 25 to 50%. Calcium absorption varies depending on dietary factors and vitamin D status.
Onset of ActionAntihistamine effects typically begin within 30 to 60 minutes after oral administration. Calcium supplementation effects are not immediate and depend on ongoing intake.
Peak Plasma TimePeak plasma concentration of chlorpheniramine is reached in about 2 to 6 hours. Calcium levels peak variably depending on absorption.
Duration of ActionThe antihistamine effect of chlorpheniramine lasts approximately 4 to 6 hours, but sedative effects may persist longer. Calcium effects are continuous with regular supplementation.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Calcium Gluconate dissociates into calcium ions, which are essential for numerous physiological processes including bone mineralization, muscle contraction, nerve impulse transmission, and blood coagulation. Chlorpheniramine Maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors on effector cells, thereby preventing histamine-mediated allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation. Additionally, chlorpheniramine has anticholinergic properties that contribute to its drying effects on respiratory secretions.

Mechanism Steps

1
Calcium supplementation: Calcium gluconate dissociates to release calcium ions, which are absorbed and distributed to tissues where they participate in bone formation, muscle function, and nerve signaling.
2
Histamine H1 receptor blockade: Chlorpheniramine binds to H1 receptors on cells in the respiratory tract, blood vessels, and skin, preventing histamine from triggering allergic symptoms.
3
Anticholinergic effects: Chlorpheniramine also blocks muscarinic receptors, leading to reduced secretions and potential side effects like dry mouth and drowsiness.

💡 How to Take allercalcin tablet

Strength: Each tablet contains Calcium Gluconate 500 mg and Chlorpheniramine Maleate 4 mg.

1Take this medicine orally with a full glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take with food to reduce stomach upset.
4Follow the prescribed schedule exactly.
5Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally one to three times daily, depending on the severity of symptoms and clinical response. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and other medications being taken. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing.
Elderly DosageElderly patients may be more sensitive to the sedative and anticholinergic effects of chlorpheniramine. Use with caution and consider lower doses. Monitor for confusion, falls, and urinary retention.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary based on creatinine clearance. Monitor serum calcium and renal function.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Chlorpheniramine is metabolized in the liver; dose reduction may be required.
Maximum Daily DoseThe maximum daily dose should not exceed 3 tablets in 24 hours, unless otherwise directed by a physician. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves calcium absorption.
Alcohol
Avoid
Increases sedation and impairs motor skills.
Caffeine
Limit
May counteract drowsiness but can increase heart rate.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of allercalcin tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (5-15%))
Sip water, chew sugar-free gum, or use saliva substitutes. Consult doctor if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid sudden movements.
Nausea (Uncommon (1-5%))
Take with food to reduce stomach upset. If persistent, consult doctor.
Constipation (Uncommon (1-5%))
Increase fiber and fluid intake. Consult doctor if it continues.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, tongue, or throat, difficulty breathing, or severe rash.
Hypercalcemia (Rare (<0.1%))
Contact your doctor if you experience excessive thirst, frequent urination, confusion, or muscle weakness.
Cardiac arrhythmias (Rare (<0.1%))
Seek immediate medical attention if you notice palpitations, irregular heartbeat, or fainting.
Seizures (Very rare (<0.01%))
Call emergency services if seizures occur.

⚠️ Rare Side Effects

Blood dyscrasias (e.g., agranulocytosis, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor immediately.
Hepatotoxicity
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Moderate
Diazepam Major
Fluoxetine Moderate
Hydrochlorothiazide Moderate
Atropine Moderate
Levodopa Moderate
Metoclopramide Minor
Digoxin Moderate
Tetracycline Moderate
Phenytoin Moderate

🚨 Major Interactions

  • Central nervous system depressants (e.g., alcohol, benzodiazepines, opioids)
  • Monoamine oxidase inhibitors (MAOIs)
  • Thiazide diuretics

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
  • Calcium channel blockers

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can enhance the sedative effects of chlorpheniramine, leading to increased drowsiness, dizziness, and impaired judgment. This combination can also increase the risk of respiratory depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to calcium gluconate or chlorpheniramine","Hypercalcemia","Hypercalciuria","Severe renal impairment","Narrow-angle glaucoma","Prostatic hypertrophy or bladder neck obstruction","Use with MAO inhibitors"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in elderly patients due to increased risk of confusion and falls.","Monitor calcium levels in patients with renal disease.","May cause dry mouth, constipation, and urinary retention.","Do not exceed recommended dose.","Consult doctor before use in pregnancy or breastfeeding."]

🤱 Lactation Safety

Chlorpheniramine may pass into breast milk and cause drowsiness in the infant. Calcium is safe. Consult your doctor before use during breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, confusion, tachycardia, hallucinations, and hypercalcemia. Seek emergency medical attention immediately. Treatment is supportive and symptomatic. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs, serum calcium, and electrolytes. There is no specific antidote for chlorpheniramine; physostigmine may be used cautiously in severe anticholinergic toxicity.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness. Avoid alcohol and other central nervous system depressants while taking this medicine. Inform your doctor if you have kidney disease, heart disease, glaucoma, or difficulty urinating. Do not take calcium supplements or antacids containing calcium without consulting your doctor, as this may increase the risk of high calcium levels. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more susceptible to the sedative and anticholinergic effects of chlorpheniramine, such as confusion, dry mouth, constipation, and urinary retention. They may also be at higher risk of hypercalcemia from calcium supplementation. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of chlorpheniramine during pregnancy is not well established, and calcium supplementation should be based on individual needs.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. Chlorpheniramine may interact with anesthetic agents and increase sedation. Calcium levels may need monitoring.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it can cause dry mouth and may interact with local anesthetics or sedatives used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a balanced diet rich in calcium and vitamin D.
🥗
Stay hydrated to reduce dry mouth and constipation.
😴
Avoid alcohol and other sedatives.
💧
Engage in regular weight-bearing exercises to strengthen bones.
🧘
Get adequate sleep to manage allergy symptoms.
🌞
Use air purifiers to reduce allergen exposure.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness, which can affect your coordination. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you exercise outdoors, be aware of allergen exposure.

🥗 Diet Recommendations

Include calcium-rich foods like dairy, leafy greens, and fortified cereals.
Ensure adequate vitamin D through sunlight or supplements.
Limit caffeine and alcohol intake.
Stay well hydrated to prevent constipation.
Avoid excessive calcium supplements without medical advice.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may impair your ability to drive, operate machinery, or perform tasks requiring mental alertness. It is advisable to avoid such activities until you know how it affects you. Inform your employer if your job involves safety-sensitive tasks.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may advise tapering or stopping. Abrupt discontinuation is generally not associated with withdrawal, but medical guidance is recommended.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance to the sedative effects, but dependence is rare. Prolonged high-dose calcium intake may increase the risk of kidney stones and hypercalcemia. Regular monitoring of serum calcium and renal function is advised for long-term use. Chlorpheniramine may cause cognitive impairment with prolonged use in the elderly.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Non-sedating antihistamines

May be used if drowsiness is problematic, but lack calcium supplementation.

Evidence: Well-established
Calcium-rich diet and vitamin D supplements

Can address calcium deficiency without medication.

Evidence: Well-established
Allergen avoidance

Reducing exposure to allergens can minimize need for antihistamines.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before vaccination if you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing times gradually as advised by your doctor. Keep it in your carry-on luggage to avoid loss. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies and mild calcium deficiency
She was prescribed this medicine for her allergic rhinitis and calcium supplementation. After taking it as directed with food, her sneezing and runny nose improved within a few days. She experienced mild drowsiness initially, which subsided after a week. She was advised not to drive until she knew how it affected her.
💡 Lesson: Taking the medicine with food and avoiding driving until you know its effects can improve tolerability and safety.
👤 A 60-year-old man with chronic urticaria and osteoporosis
He was started on this medicine for itching and calcium support. His itching reduced significantly, but he developed dry mouth and constipation. His doctor advised him to increase fluid and fiber intake, which helped. Regular monitoring of serum calcium was done to prevent hypercalcemia.
💡 Lesson: Older patients may experience more anticholinergic side effects and require monitoring for calcium levels.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The antihistamine effect usually starts within 30 to 60 minutes, but full relief may take a few days of regular use.

Q: Can I take it on an empty stomach?

A: It is best taken with food to reduce stomach upset.

Q: Is it safe to take with other allergy medicines?

A: Consult your doctor before combining with other antihistamines or sedatives to avoid additive effects.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for the next dose, skip it and continue your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for allercalcin tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for any allergy without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under medical supervision.
  • Myth: It is safe to drive after taking this medicine.
    Fact: This medicine can cause drowsiness and impair your ability to drive or operate machinery.
  • Myth: More calcium is always better.
    Fact: Excessive calcium can lead to hypercalcemia, which can be dangerous. Take only as prescribed.

🔄 Alternative Options

Generic Alternatives

  • Calcium Gluconate + Chlorpheniramine Maleate tablets from other manufacturers

Brand Alternatives

  • Allercalcin Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Calcium Gluconate 500mg + Chlorpheniramine Maleate 4mg","uses":"Allergic rhinitis, calcium deficiency","sedation":"Moderate to high"},{"medicine":"Calcium carbonate + Chlorpheniramine","composition":"Calcium carbonate 500mg + Chlorpheniramine 4mg","uses":"Similar","sedation":"Moderate to high"},{"medicine":"Chlorpheniramine alone","composition":"Chlorpheniramine Maleate 4mg","uses":"Allergic conditions only","sedation":"Moderate to high"}]

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