Alfox OZ 50mg/5ml/125mg/5ml Syrup - Uses, Price, Side Effects
What is alfox oz 50mg/5ml/125mg/5ml syrup used for?
Alfox OZ Syrup contains Ofloxacin (50mg/5ml) and Ornidazole (125mg/5ml). It is used to treat gastrointestinal infections such as diarrhea and dysentery caused by bacteria and protozoa. Ofloxacin stops bacterial growth, while Ornidazole kills parasites, providing dual action against mixed infections.
- Generic Name: Ofloxacin + Ornidazole
- Manufacturer: Alliaance Biotech
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ alfox oz 50mg/5ml/125mg/5ml syrup Uses & Benefits
Gastrointestinal infections, diarrhea, dysentery, intra-abdominal infections
Off-label uses: Pelvic inflammatory disease, prostatitis
๐ Drug Information
| Generic Name(s) | Ofloxacin + Ornidazole |
| Brand Name | Assault Novo 200 mg/500 mg Tablet |
| Manufacturer | Alliaance Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibiotic + Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication; Ornidazole disrupts DNA structure in anaerobic organisms
Mechanism Steps
๐ก How to Take alfox oz 50mg/5ml/125mg/5ml syrup
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of alfox oz 50mg/5ml/125mg/5ml syrup
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Metallic taste
๐จ Serious Side Effects
- Tendon rupture
- Peripheral neuropathy
- QT prolongation
- Seizures
- Clostridium difficile colitis
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Stevens-Johnson syndrome
- Hepatotoxicity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Antacids | Moderate | Reduced absorption of Ofloxacin |
| NSAIDs | Moderate | Increased risk of CNS stimulation |
๐จ Major Interactions
- Warfarin
- Antidiabetic agents
- QT-prolonging drugs
โก Moderate Interactions
- NSAIDs
- Corticosteroids
- Antacids containing magnesium or aluminum
โน๏ธ Minor Interactions
- Caffeine
- Theophylline
๐ฝ๏ธ Food Interactions
Avoid dairy products, antacids, and iron supplements within 2 hours of dosing
๐ท Alcohol Interaction
Avoid alcohol; may cause disulfiram-like reaction with Ornidazole
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to fluoroquinolones or nitroimidazoles, epilepsy, history of tendon disorders with quinolones, pregnancy, lactation
๐ Monitoring Parameters
Renal function, liver function, blood glucose, ECG for QT prolongation
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; no specific antidote; hemodialysis may help
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double dose