agra 50mg tablet - Uses, Price, Side Effects & Substitutes
What is agra 50mg tablet used for?
Assurans Tablet (Sildenafil) is used to treat SEX STIMULANTS REJUVENATORS. It contains Sildenafil (50mg), which Inhibits phosphodiesterase type 5 (PDE5), increasing cGMP levels in corpus caver. Always consult your doctor before use. Take as prescribed.
- Generic Name: Sildenafil
- Manufacturer: Alliaance Biotech
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ agra 50mg tablet Uses & Benefits
Treatment of erectile dysfunction; pulmonary arterial hypertension (as Revatio).
Off-label uses: Raynaud's phenomenon, altitude sickness, female sexual arousal disorder.
๐ Drug Information
| Generic Name(s) | Sildenafil |
| Brand Name | Assurans Tablet |
| Manufacturer | Alliaance Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | SEX STIMULANTS REJUVENATORS |
| Action Class | Phosphodiesterase-V inhibitors |
| Route of Administration | Oral. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits phosphodiesterase type 5 (PDE5), increasing cGMP levels in corpus cavernosum, leading to smooth muscle relaxation and increased blood flow.
Mechanism Steps
๐ก How to Take agra 50mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of agra 50mg tablet
โ Common Side Effects
- Headache
- Flushing
- Dyspepsia
- Nasal congestion
- Visual disturbances (blurred vision, blue tinge)
๐จ Serious Side Effects
- Priapism (prolonged erection >4 hours)
- Sudden hearing loss
- Non-arteritic anterior ischemic optic neuropathy (NAION)
- Hypotension
โ ๏ธ Rare Side Effects
- Seizures
- Anaphylaxis
- Stevens-Johnson syndrome
- Prolonged QT interval
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Nitroglycerin | Major | Severe hypotension, syncope, myocardial infarction risk |
| Ritonavir | Moderate | Increased sildenafil exposure (AUC up to 11-fold) |
| Doxazosin | Moderate | Additive hypotensive effect |
| Grapefruit juice | Minor | Slight increase in sildenafil levels |
๐จ Major Interactions
- Nitrates (e.g., nitroglycerin, isosorbide mononitrate)
- Nitric oxide donors (e.g., amyl nitrite)
- Guanylate cyclase stimulators (e.g., riociguat)
โก Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, erythromycin)
- CYP3A4 inducers (e.g., rifampin, phenytoin)
- Alpha-blockers (e.g., doxazosin, tamsulosin)
โน๏ธ Minor Interactions
- Antacids (aluminum/magnesium hydroxide)
- Grapefruit juice
๐ฝ๏ธ Food Interactions
High-fat meals delay absorption and reduce peak plasma concentration.
๐ท Alcohol Interaction
Alcohol may transiently impair erectile function; no direct pharmacokinetic interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Concurrent use of nitrates or nitric oxide donors; hypersensitivity; severe hepatic impairment; hypotension; recent stroke or MI; retinitis pigmentosa.
๐ Monitoring Parameters
Blood pressure, heart rate, visual symptoms, hearing loss.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk in animal studies.
๐ Overdose Management
Supportive care; consider gastric lavage; monitor for hypotension; no specific antidote.
โฐ Missed Dose
Take as needed; do not take more than once daily.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for agra 50mg tablet
View AllAlternative brands with exact same active ingredient (Sildenafil (50mg)):
-
powerman 50mg tabletPsychotropics India Ltd โน6.31 7.7% COSTLIER
-
vistagra 50mg tabletCadila Pharmaceuticals Ltd โน6.87 17.2% COSTLIER
-
wavegra 50mg tabletShreya Life Sciences Pvt Ltd โน7.31 24.7% COSTLIER
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exgra 50mg tabletTroikaa Pharmaceuticals Ltd โน7.50 28% COSTLIER
-
intagra 50mg tabletIntas Pharmaceuticals Ltd โน7.50 28% COSTLIER
-
power vegra 50mg tabletInd Swift Laboratories Ltd โน8.75 49.3% COSTLIER
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stayhappi sildenafil 50mg tabletSarvagunaushdhi Pvt Ltd โน8.89 51.7% COSTLIER
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eriacta 50mg tabletSun Pharmaceutical Industries Ltd โน9.62 64.2% COSTLIER
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lupigra tabletLupin Ltd โน10.00 70.6% COSTLIER
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exigra 50mg tabletWockhardt Ltd โน10.28 75.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.