akio oz oral suspension - Ofloxacin (50mg) + Ornidazole (125mg) medicine

Akio OZ Oral Suspension - Uses, Price, Side Effects

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๐Ÿญ Shakam Lifesciences ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is akio oz oral suspension used for?

Akio OZ Oral Suspension is a combination medicine used to treat gastrointestinal infections such as diarrhea and dysentery caused by bacteria and parasites. It contains Ofloxacin (an antibiotic) and Ornidazole (an antiprotozoal), which work by stopping the growth of microorganisms and killing them. This helps relieve symptoms like loose stools, abdominal pain, and fever.

  • Generic Name: Ofloxacin + Ornidazole
  • Manufacturer: Shakam Lifesciences
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š akio oz oral suspension Uses & Benefits

Gastrointestinal infections, diarrhea, dysentery, intra-abdominal infections

Off-label uses: Pelvic inflammatory disease, prostatitis

๐Ÿ“‹ Drug Information

Generic Name(s)Ofloxacin + Ornidazole
Brand NameAssault Novo 200 mg/500 mg Tablet
ManufacturerShakam Lifesciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntibiotic + Antiprotozoal
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract
DistributionDistributes widely into body tissues and fluids
Protein BindingOfloxacin: 20-25%; Ornidazole: <15%
MetabolismOfloxacin: Hepatic (minimal); Ornidazole: Hepatic via CYP450
Half-LifeOfloxacin: 4-5 hours; Ornidazole: 12-14 hours
ExcretionOfloxacin: Renal (80-90% unchanged); Ornidazole: Renal (60-70% as metabolites)
BioavailabilityOfloxacin: 98%; Ornidazole: 90%
Onset of ActionWithin 1-2 hours
Peak Plasma TimeOfloxacin: 1-2 hours; Ornidazole: 2-4 hours
Duration of ActionUp to 24 hours

How It Works

Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication; Ornidazole disrupts DNA structure in anaerobic organisms

Mechanism Steps

1Ofloxacin enters bacterial cell and inhibits DNA gyrase and topoisomerase IV
2Inhibition prevents DNA supercoiling and replication
3Ornidazole enters anaerobic organisms and is reduced by bacterial nitroreductases

๐Ÿ’ก How to Take akio oz oral suspension

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of akio oz oral suspension

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Metallic taste

๐Ÿšจ Serious Side Effects

  • Tendon rupture
  • Peripheral neuropathy
  • QT prolongation
  • Seizures
  • Clostridium difficile colitis

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Stevens-Johnson syndrome
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
NSAIDs Moderate Increased risk of CNS effects
Antacids Moderate Reduced absorption of ofloxacin

๐Ÿšจ Major Interactions

  • Warfarin
  • Antidiabetic agents
  • QT-prolonging drugs

โšก Moderate Interactions

  • NSAIDs
  • Corticosteroids
  • Antacids containing magnesium or aluminum

โ„น๏ธ Minor Interactions

  • Caffeine
  • Theophylline

๐Ÿฝ๏ธ Food Interactions

Avoid dairy products, antacids, and iron supplements within 2 hours of dosing

๐Ÿท Alcohol Interaction

Avoid alcohol; may cause disulfiram-like reaction with Ornidazole

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to fluoroquinolones or nitroimidazoles, epilepsy, history of tendon disorders with quinolones, pregnancy, lactation

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, blood glucose, ECG for QT prolongation

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; no specific antidote; hemodialysis may help

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

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