agt-ls syrup - Levosalbutamol (1mg/5ml) + Ambroxol (30mg/5ml) medicine

Ascodex LS Expectorant: Complete Medicine Guide

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🏭 Syndicate Life Sciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for combination use in productive cough with bronchospasm.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or worsening shortness of breath
  • Chest pain or irregular heartbeat
  • Severe allergic reaction (rash, swelling of face/lips/throat)
  • Coughing up blood
  • High fever with chills
  • Severe dizziness or fainting
  • Yellowing of skin or eyes (jaundice)

If experiencing severe symptoms, call emergency services immediately.

What is agt-ls syrup used for?

This medicine is a combination of levosalbutamol (a bronchodilator) and ambroxol (a mucolytic) used to treat productive cough with bronchospasm. It helps loosen mucus and open airways, making it easier to breathe and cough out phlegm.

  • Generic Name: Levosalbutamol + Ambroxol
  • Manufacturer: Syndicate Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 agt-ls syrup के बारे में (Hindi Summary)

उपयोग: यह दवा लेवोसाल्बुटामोल और एम्ब्रोक्सोल का संयोजन है, जिसका उपयोग बलगम वाली खांसी और सांस की नली में संकुचन के इलाज के लिए किया जाता है। यह बलगम को पतला करके बाहर निकालने में मदद करती है और सांस की नलियों को खोलती है, जिससे सांस लेना आसान हो जाता है। यह दवा डॉक्टर के पर्चे पर ही लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, सिरदर्द, चक्कर आना, हाथ-पैर कांपना और धड़कन तेज होना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, त्वचा पर चकत्ते, या दिल की धड़कन अनियमित लगे, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को कम या ज्यादा न करें। बोतल को अच्छी तरह हिलाकर ही नापें। अगर खांसी कुछ दिनों में ठीक न हो या बुखार, सीने में दर्द या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर से मिलें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 agt-ls syrup Uses & Benefits

[{"condition":"Productive cough with bronchospasm","description":"Helps relieve cough associated with thick mucus and mild airway narrowing by thinning secretions and opening airways.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Used to ease cough and mucus clearance in acute bronchitis when both bronchospasm and thick mucus are present.","evidence":"Moderate"},{"condition":"Chronic bronchitis","description":"May help manage chronic bronchitis symptoms by improving mucus clearance and reducing bronchospasm.","evidence":"Moderate"},{"condition":"Asthma with excessive mucus","description":"Sometimes used as add-on therapy for asthma when thick mucus is a prominent symptom, but not as a sole treatment.","evidence":"Limited"}]

Off-label uses: [{"condition":"Post-operative pulmonary complications prevention","description":"Occasionally used off-label to prevent mucus plugging after surgery in high-risk patients.","evidence":"Limited"}]

Primary treatment for: Productive cough with bronchospasm

Also treats: Acute bronchitis, Chronic bronchitis, Asthma with excessive mucus

📋 Drug Information

Generic Name(s)Levosalbutamol + Ambroxol
Brand NameAmrox-LS Junior Syrup
ManufacturerSyndicate Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassBronchodilator + Mucolytic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not freeze. Keep the bottle tightly closed. Keep out of reach of children.
Shelf Life24 months from the date of manufacture, unless otherwise specified on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always shake the bottle well before measuring the dose to ensure uniform mixing.
2
Use the measuring cup provided; household spoons are not accurate.
3
Take this medicine with food if it causes stomach upset.
4
Avoid driving or operating machinery if you feel dizzy or shaky.
5
Do not use this medicine for more than the recommended duration without consulting your doctor.
6
If you have heart problems, diabetes, or thyroid issues, inform your doctor before taking this medicine.
7
Keep track of your symptoms; if cough persists beyond 7 days or worsens, seek medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with phlegm
This medicine is commonly prescribed for this.
Likely Use
✅
Wheezing
Levosalbutamol helps open airways.
Likely Use
❌
Dry cough
This medicine is not for dry cough; it is for productive cough.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevosalbutamol is rapidly absorbed from the gastrointestinal tract after oral administration. Ambroxol is also well absorbed orally. However, oral bioavailability of levosalbutamol is reduced due to first-pass metabolism. Specific absorption data for this combination product are not established from the available information.
DistributionLevosalbutamol distributes widely into body tissues, including the lungs. Ambroxol distributes into lung tissue, bronchial secretions, and plasma. Protein binding information for this combination is not established from the available information.
Protein BindingNot established from the available information.
MetabolismLevosalbutamol undergoes extensive first-pass metabolism in the liver, primarily by sulfation. Ambroxol is metabolized in the liver by conjugation. Specific metabolic pathways for the combination are not established from the available information.
Half-LifeThe elimination half-life of levosalbutamol is approximately 3 to 4 hours. The elimination half-life of ambroxol is approximately 7 to 12 hours. These values may vary based on individual factors.
ExcretionLevosalbutamol and its metabolites are primarily excreted in urine. Ambroxol is excreted mainly in urine as metabolites. Specific excretion data for the combination are not established from the available information.
BioavailabilityOral bioavailability of levosalbutamol is reduced due to first-pass metabolism. Bioavailability of ambroxol is approximately 70-80%. Specific bioavailability for this combination product is not established from the available information.
Onset of ActionBronchodilation from levosalbutamol typically begins within 15-30 minutes after oral administration. Mucolytic effects of ambroxol may take several hours to become noticeable.
Peak Plasma TimePeak plasma concentrations of levosalbutamol are reached within 1-2 hours. For ambroxol, peak levels occur within 1-3 hours. Specific data for this combination are not established from the available information.
Duration of ActionBronchodilation from oral levosalbutamol lasts approximately 4-6 hours. The mucolytic effect of ambroxol lasts for several hours. The duration of action for the combination may vary.

How It Works

This medicine works through two complementary mechanisms. Levosalbutamol selectively stimulates beta-2 adrenergic receptors in the smooth muscles of the airways, which leads to relaxation of the bronchial muscles and widening of the airways. Ambroxol increases the production of serous fluid in the respiratory tract and reduces mucus viscosity, making it easier to cough up. Additionally, ambroxol may stimulate surfactant production and enhance ciliary movement, further aiding mucus clearance.

Mechanism Steps

1
Beta-2 receptor stimulation: Levosalbutamol binds to beta-2 adrenergic receptors on airway smooth muscle cells, activating intracellular signaling that leads to muscle relaxation.
2
Bronchodilation: Relaxation of bronchial smooth muscles widens the airways, decreasing resistance to airflow and making breathing easier.
3
Mucus thinning: Ambroxol alters the structure of mucus by breaking down acidic mucopolysaccharide fibers, reducing viscosity and making it less sticky.
4
Enhanced mucus clearance: Ambroxol also stimulates ciliary beat frequency and surfactant production, helping to move thinned mucus upward for expulsion by coughing.

💡 How to Take agt-ls syrup

Strength: Each 5 ml contains Levosalbutamol 1 mg and Ambroxol 30 mg.

1Shake the bottle well before each use.
2Use the measuring cup or spoon provided to measure the exact dose.
3Take the medicine orally with or without food.
4If it upsets your stomach, take it with a meal or snack.
5Do not mix with other liquids unless instructed by your doctor.
6After use, close the bottle tightly and store as directed.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5-10 ml orally two to three times a day, or as directed by your doctor. The exact dose depends on the severity of your condition, your age, weight, and kidney and liver function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Always use the measuring cup provided.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially cardiovascular effects. Use with caution and follow your doctor's instructions. Dose adjustment may be necessary based on kidney and liver function.
Renal ImpairmentDose adjustment may be needed in patients with severe renal impairment. Consult your doctor for appropriate dosing.
Hepatic ImpairmentDose adjustment may be needed in patients with severe hepatic impairment. Consult your doctor for appropriate dosing.
Maximum Daily DoseThe maximum recommended daily dose is 30 ml per day, but this may vary based on your doctor's prescription. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
No known interaction
No significant interaction reported.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of agt-ls syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Tremor (Common (5-10%))
Usually mild and temporary. Report to doctor if bothersome.
Palpitations (Uncommon (1-5%))
If you feel your heart racing or pounding, contact your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, or throat, or difficulty breathing.
Irregular heartbeat (arrhythmia) (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations, chest pain, or fainting.
Severe skin reactions (Rare (<0.1%))
Stop the medicine and seek immediate medical attention if you develop a severe rash, blisters, or peeling skin.

⚠️ Rare Side Effects

Hypokalemia (low potassium)
Report muscle weakness, cramps, or palpitations to your doctor.
Paradoxical bronchospasm
If breathing worsens after taking this medicine, stop and seek immediate medical help.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Furosemide Moderate
Corticosteroids Moderate
Digoxin Moderate
Ipratropium Minor

🚨 Major Interactions

  • Beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Corticosteroids
  • Digoxin

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and cardiovascular side effects. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to levosalbutamol, ambroxol, or any component of the formulation","Severe cardiovascular disease (e.g., severe hypertension, arrhythmias)","Hyperthyroidism","Diabetes mellitus (uncontrolled)","Severe hepatic or renal impairment (relative contraindication)"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular disorders, including coronary insufficiency, arrhythmias, and hypertension.","May cause tremor, nervousness, or dizziness; avoid driving or operating machinery until effects are known.","Not recommended for children under the age specified by the prescribing doctor.","Do not exceed the recommended dose; excessive use may lead to severe cardiovascular effects.","If symptoms persist or worsen, consult a doctor; do not self-medicate for prolonged periods.","Inform your doctor if you have a history of seizures, thyroid disorders, or diabetes.","Use with caution in elderly patients who may be more sensitive to side effects."]

🤱 Lactation Safety

It is not known whether levosalbutamol and ambroxol are excreted in human breast milk. Caution is advised when used during breastfeeding. Consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose may cause severe tachycardia, tremor, palpitations, hypertension, and hypokalemia. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. Monitor vital signs and electrolytes. There is no specific antidote for levosalbutamol or ambroxol.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Shake the bottle well before each use if it is a suspension. Use a proper measuring cup or spoon to measure the dose accurately. Do not use this medicine for a longer duration than recommended. If your cough does not improve within a few days or if you develop fever, chest pain, or difficulty breathing, contact your doctor immediately. Avoid driving or operating heavy machinery if you feel dizzy or shaky after taking this medicine. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep this medicine out of the reach of children. Store it as directed on the label.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiovascular effects of levosalbutamol, such as increased heart rate and blood pressure. Use with caution and monitor closely. Dose adjustment may be needed based on kidney and liver function.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy is not well established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your surgeon and anesthesiologist about this medicine. It may interact with certain anesthetic agents and affect heart rate and blood pressure.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth or interact with certain medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier to add moisture to the air.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Practice deep breathing exercises to improve lung function.
🧘
Get plenty of rest to help your body recover.
🌞
Wash your hands frequently to prevent infections.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have difficulty breathing or feel dizzy. Light activity like walking may be beneficial, but consult your doctor before starting any exercise routine.

🥗 Diet Recommendations

Drink warm fluids like herbal tea or soup to soothe the throat.
Include foods rich in vitamin C to support immunity.
Avoid cold drinks and ice cream as they may worsen cough.
Eat a balanced diet with plenty of fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tremor, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to rest and avoid strenuous work while recovering from respiratory illness.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine should be monitored by a doctor. Prolonged use of levosalbutamol may lead to tolerance and reduced effectiveness. Ambroxol is generally well-tolerated for short-term use. Regular monitoring of heart rate, blood pressure, and potassium levels may be needed. Do not use for extended periods without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and soothe airways.

Evidence: Traditional
Saline nasal irrigation

Can help clear nasal congestion.

Evidence: Limited
Chest physiotherapy

Techniques to help clear mucus from lungs.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are due for a vaccination, inform your doctor about all medicines you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case of customs checks. Store it at room temperature and protect it from extreme heat or cold. If crossing time zones, adjust dosing times gradually as advised by your doctor. Keep it in your carry-on luggage if flying.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He was prescribed this medicine for a productive cough and wheezing. After taking it as directed for 5 days, his cough became more productive and breathing improved. He experienced mild nausea initially, which subsided when he took it with food.
💡 Lesson: Taking the medicine with food can reduce stomach upset and improve tolerability.
👤 A 60-year-old woman with chronic bronchitis
She used this medicine during exacerbations of chronic bronchitis. It helped loosen her chest congestion and made it easier to cough out mucus. She was advised to monitor her heart rate due to a history of palpitations.
💡 Lesson: Elderly patients with heart conditions should use this medicine with caution and under medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Bronchodilation begins within 15-30 minutes, but the full mucolytic effect may take a few hours. You may notice easier breathing and looser cough within a day.

Q: Can I take it with other cough medicines?

A: Do not take other cough medicines without consulting your doctor, as they may contain overlapping ingredients or interact.

Q: Is it safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate use in children.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for agt-ls syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: It is specifically for productive cough with bronchospasm. It is not effective for dry cough or cough due to other causes.
  • Myth: More dose means faster relief.
    Fact: Taking more than prescribed can cause serious side effects. Always follow your doctor's advice.
  • Myth: It is safe to take for a long time without doctor's supervision.
    Fact: Prolonged use should be monitored by a doctor. Do not self-medicate for extended periods.

🔄 Alternative Options

Generic Alternatives

  • Levosalbutamol + Ambroxol oral solution (generic)

Brand Alternatives

  • Ascodex LS Expectorant

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Levosalbutamol + Ambroxol","key_feature":"Combination of bronchodilator and mucolytic"},{"medicine":"Salbutamol + Ambroxol","composition":"Salbutamol + Ambroxol","key_feature":"Similar but uses salbutamol instead of levosalbutamol"},{"medicine":"Ambroxol alone","composition":"Ambroxol","key_feature":"Only mucolytic, no bronchodilator"}]

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