coughex-ls syrup - Ambroxol (30mg/5ml) + Levosalbutamol (1mg/5ml) medicine

Ascoril LS Syrup: Complete Guide to Uses, Dosage, Side Effects, and Safety

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🏭 Sun Life Sciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or worsening breathlessness
  • Chest pain or palpitations
  • Severe allergic reaction (rash, swelling, hives)
  • Blood in cough or vomit
  • Severe dizziness or fainting
  • Irregular heartbeat
  • Yellowing of eyes or skin

If experiencing severe symptoms, call emergency services immediately.

What is coughex-ls syrup used for?

This medicine is a combination syrup containing ambroxol and levosalbutamol. It is used to treat productive cough with thick mucus and mild breathing difficulty by thinning mucus and opening airways. It is available by prescription only and should be taken as directed by a doctor.

  • Generic Name: Ambroxol + Levosalbutamol
  • Manufacturer: Sun Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 coughex-ls syrup के बारे में (Hindi Summary)

उपयोग: यह दवा एक प्रिस्क्रिप्शन सिरप है जिसमें एम्ब्रोक्सोल और लेवोसाल्बुटामोल दो सक्रिय तत्व होते हैं। यह कफ और बलगम से जुड़ी समस्याओं में उपयोग की जाती है। यह बलगम को पतला करके बाहर निकालने में मदद करती है और सांस की नली को खोलती है जिससे सांस लेने में आसानी होती है। यह दवा ब्रोंकाइटिस, अस्थमा और सीओपीडी जैसी बीमारियों में डॉक्टर की सलाह पर दी जाती है। इसे बिना डॉक्टर की सलाह के नहीं लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, सिरदर्द, चक्कर आना, हाथ-पैर कांपना और दिल की धड़कन तेज होना शामिल हैं। कभी-कभी एलर्जी, सांस लेने में तकलीफ या दिल की अनियमित धड़कन जैसी गंभीर समस्याएं भी हो सकती हैं। अगर ऐसा कुछ हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप मात्रा कम या ज्यादा न करें। हर बार उपयोग से पहले बोतल को अच्छी तरह हिलाएं और मापने वाले कप से ही दवा निकालें। अगर आपको चक्कर या कंपन महसूस हो तो वाहन न चलाएं। दिल, ब्लड प्रेशर, डायबिटीज या थायरॉइड की समस्या हो तो डॉक्टर को पहले बताएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 coughex-ls syrup Uses & Benefits

[{"condition":"Productive cough with thick mucus","description":"Helps loosen and clear mucus from the airways, making cough more productive.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Provides symptomatic relief by reducing mucus viscosity and easing bronchospasm.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD) exacerbation","description":"May be used as an adjunct to help clear secretions and improve airflow.","evidence":"Moderate"},{"condition":"Asthma with mucus plugging","description":"Sometimes prescribed to help manage mucus in asthma, but not as a primary controller.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prevention of respiratory distress syndrome in preterm infants","description":"Ambroxol has been studied off-label for this purpose, but it is not a standard use for this syrup.","evidence":"Limited"}]

Primary treatment for: Productive cough with bronchospasm

Also treats: Acute bronchitis, COPD exacerbation, Asthma with mucus plugging

📋 Drug Information

Generic Name(s)Ambroxol + Levosalbutamol
Brand NameAscoril LS Junior Syrup
ManufacturerSun Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Beta-2 Adrenergic Agonist
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not freeze. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture. After opening, use within 30 days unless otherwise specified on the label.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this medicine after assessing the type of cough; it is not for dry cough.
2
Advise patients to take it with food if they experience stomach upset.
3
Warn patients about potential dizziness and tremor; advise caution while driving.
4
Monitor heart rate and blood pressure in patients with cardiovascular disease.
5
Do not prescribe for children under 2 years without specialist consultation.
6
Review after 7 days if symptoms persist; consider alternative diagnosis.
7
Check for interactions with beta-blockers and MAOIs before prescribing.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
Dry cough
This medicine is not effective for dry cough.
Not Primary
Fever
This medicine is not a primary fever reducer.
Not Primary
Wheezing
Levosalbutamol component helps with wheezing.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmbroxol is rapidly absorbed from the gastrointestinal tract after oral administration. Levosalbutamol is also well absorbed orally, but it undergoes some first-pass metabolism. Specific bioavailability data for this combination syrup is not established from the available information.
DistributionAmbroxol distributes widely into body tissues, including lung tissue, and crosses the blood-brain barrier to some extent. Levosalbutamol distributes into the lungs and other tissues. Protein binding information for both agents is not established from the available information.
Protein BindingNot established from the available information.
MetabolismAmbroxol is metabolized in the liver primarily by conjugation to glucuronic acid and sulfate. Levosalbutamol is metabolized in the liver by sulfation, primarily via sulfotransferase enzymes.
Half-LifeThe elimination half-life of ambroxol is approximately 7 to 12 hours. The elimination half-life of levosalbutamol is approximately 3 to 4 hours. These values may vary based on individual factors.
ExcretionAmbroxol and its metabolites are excreted mainly in the urine. Levosalbutamol and its metabolites are also excreted primarily in the urine, with a small amount in feces.
BioavailabilityOral bioavailability of ambroxol is approximately 70-80% due to first-pass metabolism. Oral bioavailability of levosalbutamol is not well established but is considered lower than inhaled administration.
Onset of ActionThe bronchodilator effect of levosalbutamol typically begins within 15-30 minutes after oral administration. Ambroxol's mucolytic effect may take several hours to become noticeable.
Peak Plasma TimePeak plasma concentrations of ambroxol are reached approximately 1-3 hours after oral administration. Peak plasma levels of levosalbutamol are reached within 1-2 hours.
Duration of ActionThe bronchodilator effect of levosalbutamol lasts about 4-6 hours. Ambroxol's mucolytic effect lasts longer, typically 8-12 hours, depending on the dose and individual factors.

How It Works

This medicine combines two active ingredients with complementary actions. Ambroxol is a mucolytic that reduces the viscosity of mucus by breaking down acidic mucopolysaccharide fibers and stimulating surfactant production, making secretions easier to expel. Levosalbutamol is a selective beta-2 adrenergic agonist that relaxes bronchial smooth muscle, leading to bronchodilation and improved airflow. Together, they help relieve cough and breathing difficulty associated with excess mucus and mild bronchoconstriction.

Mechanism Steps

1
Ambroxol reduces mucus viscosity: Ambroxol breaks down acidic mucopolysaccharides and stimulates surfactant production, thinning thick mucus.
2
Levosalbutamol relaxes airway muscles: Levosalbutamol binds to beta-2 receptors on bronchial smooth muscle, causing relaxation and widening of the airways.
3
Improved mucociliary clearance: Thinner mucus combined with open airways allows cilia to move secretions more effectively, leading to a productive cough.

💡 How to Take coughex-ls syrup

Strength: Each 5 ml of syrup contains Ambroxol 30 mg and Levosalbutamol 1 mg.

1Shake the bottle well before each use.
2Measure the prescribed dose using the measuring cup or spoon provided.
3Take the medicine orally, with or without food.
4If it upsets your stomach, take it with a meal or snack.
5After taking, rinse your mouth with water to prevent any residue.
6Close the bottle tightly and store as directed.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5-10 ml taken orally two to three times a day, or as prescribed by your doctor. The dose may vary depending on the severity of your condition and your response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing based on your child's age and weight.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially cardiovascular effects. Dose should be individualized by a clinician, and monitoring for side effects is recommended.
Renal ImpairmentDose adjustment may be needed in patients with severe renal impairment. Consult your doctor for appropriate dosing.
Hepatic ImpairmentDose adjustment may be needed in patients with severe hepatic impairment. Consult your doctor for appropriate dosing.
Maximum Daily DoseThe maximum recommended daily dose for adults is 30 ml (6 teaspoons) per day, but this may vary based on medical advice. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
No known interaction
No significant interaction reported.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of coughex-ls syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce stomach upset. If nausea persists, consult your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated and rest. Consult doctor if severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Tremor (Common (5-10%))
Usually mild and temporary. If it interferes with daily activities, consult your doctor.
Increased heart rate (Common (5-10%))
Monitor your pulse. If you notice persistent fast heartbeat, contact your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling of face or throat, or difficulty breathing.
Irregular heartbeat (arrhythmia) (Rare (<0.1%))
Contact your doctor immediately if you feel palpitations, chest pain, or fainting.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek emergency care if you develop painful rash, blisters, or peeling skin.

⚠️ Rare Side Effects

Bronchospasm
Seek immediate medical help if breathing becomes more difficult after taking this medicine.
Hypokalemia (low potassium)
Report muscle weakness or cramps to your doctor. Blood tests may be needed.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Furosemide Moderate
Corticosteroids Moderate
Digoxin Moderate
Ipratropium Minor
Amoxicillin Minor

🚨 Major Interactions

  • Beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Corticosteroids
  • Digoxin

🍷 Alcohol Interaction

Alcohol may increase the sedative and cardiovascular effects of this medicine, leading to dizziness, drowsiness, and increased heart rate. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ambroxol, levosalbutamol, or any component of the syrup","Severe cardiovascular disease including severe arrhythmias","Severe hepatic or renal impairment without medical supervision","Use in children under 2 years of age (unless specifically prescribed)","Concomitant use with beta-blockers (unless absolutely necessary)"]

⚠️ Warnings & Precautions

["Use with caution in patients with heart disease, hypertension, diabetes, or thyroid disorders.","May cause dizziness or tremor; avoid driving or operating machinery until you know how it affects you.","Do not exceed the recommended dose; higher doses may increase risk of side effects.","If symptoms persist or worsen after 7 days, consult your doctor.","Do not use for chronic cough without medical evaluation.","Keep out of reach of children.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

It is not known whether ambroxol and levosalbutamol are excreted in human breast milk. Caution is advised when used during breastfeeding. Consult your doctor before use.

💊 Overdose Management

Overdose may cause severe tachycardia, tremor, nausea, vomiting, and hypotension. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and electrolytes.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose on your own. Shake the bottle well before each use and measure the dose with the provided measuring cup or spoon. Avoid driving or operating heavy machinery if you feel dizzy or shaky after taking this medicine. Inform your doctor if you have heart problems, high blood pressure, diabetes, or thyroid disorders before starting this medicine. Do not use this medicine for more than the recommended duration without consulting your doctor. Keep it out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiovascular effects of levosalbutamol. Dose adjustment and close monitoring of heart rate and blood pressure are recommended.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. The safety of this combination during pregnancy is not well established.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, inform your surgeon and anesthesiologist that you are taking this medicine, as it may affect heart rate and blood pressure.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth or interact with medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier to keep airways moist.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Practice deep breathing exercises to improve lung function.
🧘
Get plenty of rest to support recovery.
🌞
Wash hands frequently to prevent infections.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel breathless or dizzy. Light activity like walking may be beneficial, but consult your doctor before starting any exercise routine while on this medicine.

🥗 Diet Recommendations

Include warm fluids like soups and herbal teas.
Avoid cold and processed foods that may worsen cough.
Eat fruits rich in vitamin C to boost immunity.
Include honey in warm water to soothe throat.
Avoid excessive caffeine as it may increase heart rate.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tremor, which can affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. Office work is generally safe, but take breaks if you feel dizzy.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been on it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. Prolonged use of levosalbutamol may lead to tolerance and reduced effectiveness. Regular monitoring of heart rate, blood pressure, and potassium levels may be needed. Do not use for more than the recommended duration without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and soothe airways.

Evidence: Well-established
Saline nasal irrigation

Can help clear nasal passages and reduce postnasal drip.

Evidence: Moderate
Chest physiotherapy

Techniques to help clear secretions from lungs.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are due for a vaccine, inform your doctor that you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription in case of customs checks. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, continue your regular dosing schedule as close as possible. Do not leave it in a hot car or checked luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He was prescribed this medicine for a productive cough with thick mucus. After 3 days of taking it as directed, he noticed his cough became more productive and breathing was easier. He experienced mild nausea initially but it subsided when he took it with food.
💡 Lesson: Taking this medicine with food can reduce stomach upset, and it may take a few days to see full benefit.
👤 A 60-year-old woman with COPD exacerbation
She was given this medicine along with other treatments. She reported feeling less breathless and was able to clear secretions better. However, she experienced hand tremors, which her doctor said was a known side effect and adjusted her dose.
💡 Lesson: Side effects like tremors can occur but are manageable with dose adjustment under medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The bronchodilator effect starts within 15-30 minutes, but the full mucolytic effect may take a few hours to days.

Q: Can I take this medicine with other cough medicines?

A: Do not take with other cough medicines without consulting your doctor, as ingredients may overlap and cause side effects.

Q: Is this medicine safe for children?

A: It should only be used in children under medical supervision. Dosing is not established for all age groups.

Q: Does this medicine cause drowsiness?

A: It may cause dizziness or tremor, but drowsiness is not common. Avoid driving if you feel dizzy.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for coughex-ls syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is specifically for productive cough with mucus and bronchospasm. It is not effective for dry cough or cough due to other causes.
  • Myth: It is safe to take this medicine without a prescription.
    Fact: This medicine contains levosalbutamol, which can affect heart rate and blood pressure. It should only be used under medical supervision.
  • Myth: More medicine means faster relief.
    Fact: Taking more than the prescribed dose can lead to serious side effects like rapid heartbeat and tremors. Always follow your doctor's instructions.

🔄 Alternative Options

Generic Alternatives

  • Ambroxol + Levosalbutamol syrup (various manufacturers)

Brand Alternatives

  • Ascoril LS Syrup (Glenmark Pharmaceuticals Ltd)

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Ambroxol 30mg/5ml + Levosalbutamol 1mg/5ml","primary_use":"Productive cough with bronchospasm","route":"Oral"},{"medicine":"Ambroxol + Guaifenesin","composition":"Ambroxol 30mg/5ml + Guaifenesin 50mg/5ml","primary_use":"Productive cough","route":"Oral"},{"medicine":"Levosalbutamol + Ipratropium","composition":"Levosalbutamol 1mg/5ml + Ipratropium 0.5mg/5ml","primary_use":"Bronchospasm","route":"Oral"}]

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