aramol-f 2 nasal spray - Fluticasone Furoate (27.5mcg) medicine

aramol-f 2 nasal spray - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Syndicate Life Sciences Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is aramol-f 2 nasal spray used for?

Avamys Nasal Spray (Fluticasone Furoate) is used to treat RESPIRATORY. It contains Fluticasone Furoate (27.5mcg), which Agonist at glucocorticoid receptor, leading to anti-inflammatory effects.. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Fluticasone Furoate
  • Manufacturer: Syndicate Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š aramol-f 2 nasal spray Uses & Benefits

Allergic rhinitis (seasonal and perennial).

Off-label uses: Nasal polyps

๐Ÿ“‹ Drug Information

Generic Name(s)Fluticasone Furoate
Brand NameAvamys Nasal Spray
ManufacturerSyndicate Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassGlucocorticoids
Route of AdministrationIntranasal
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionSystemic absorption is low due to low aqueous solubility and extensive first-pass metabolism.
DistributionVolume of distribution is approximately 4.2 L/kg. High plasma protein binding.
Protein Binding>99%
MetabolismHepatic via CYP3A4 to inactive metabolites.
Half-LifeApproximately 15 hours after intranasal administration.
ExcretionPrimarily fecal (approximately 90%) and urinary (<5%).
BioavailabilityLess than 1% due to low absorption and first-pass metabolism.
Onset of ActionWithin 8 hours after first dose.
Peak Plasma Time0.5-2 hours after intranasal administration.
Duration of Action24 hours.

How It Works

Agonist at glucocorticoid receptor, leading to anti-inflammatory effects.

Mechanism Steps

1Binds to glucocorticoid receptor in cytoplasm
2Receptor-ligand complex translocates to nucleus
3Modulates gene transcription of anti-inflammatory proteins

๐Ÿ’ก How to Take aramol-f 2 nasal spray

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of aramol-f 2 nasal spray

โœ… Common Side Effects

  • Epistaxis
  • Nasal ulceration
  • Headache
  • Pharyngitis

๐Ÿšจ Serious Side Effects

  • Adrenal suppression
  • Growth retardation in children
  • Glaucoma
  • Cataracts

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Nasal septal perforation
  • Osteoporosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Major Increased systemic exposure to fluticasone furoate

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component; untreated nasal mucosal infections.

๐Ÿ“Š Monitoring Parameters

Nasal symptoms, growth in children, adrenal function with prolonged use.

๐Ÿคฑ Lactation Safety

Not recommended; unknown if excreted in breast milk.

๐Ÿ’Š Overdose Management

No specific antidote; supportive care.

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for aramol-f 2 nasal spray

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Alternative brands with exact same active ingredient (Fluticasone Furoate (27.5mcg)):

Medical Note: Always consult your doctor before switching medications.

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