Agopride Injection (Leuprolide 1mg/ml) - Uses, Price, Side Effects
What is agopride injection used for?
Agopride Injection contains Leuprolide, a GnRH agonist that reduces estrogen levels. It is used to treat endometriosis, uterine fibroids, and advanced prostate cancer. By suppressing ovarian or testicular hormone production, it helps relieve symptoms and shrink abnormal tissue. Administered as a subcutaneous injection, it is typically given once a month.
- Generic Name: Leuprolide
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: X
- Prescription Required: Yes
๐ agopride injection Uses & Benefits
Endometriosis, uterine fibroids, central precocious puberty, prostate cancer (male), assisted reproduction
Off-label uses: Breast cancer, transgender hormone therapy, hirsutism
๐ Drug Information
| Generic Name(s) | Leuprolide |
| Brand Name | Agopride Injection |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | GNRH agonists/analogue |
| Route of Administration | Subcutaneous or intramuscular injection |
| Storage | Store at 20-25ยฐC; protect from light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
GnRH agonist; continuous stimulation downregulates pituitary GnRH receptors, reducing LH and FSH secretion, thereby suppressing gonadal steroid production
Mechanism Steps
๐ก How to Take agopride injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of agopride injection
โ Common Side Effects
- Hot flashes
- Sweating
- Headache
- Nausea
- Injection site reactions
- Vaginal dryness
- Decreased libido
๐จ Serious Side Effects
- Anaphylaxis
- Seizures
- Pituitary apoplexy
- Spinal cord compression
- QT prolongation
โ ๏ธ Rare Side Effects
- Osteoporosis
- Hyperglycemia
- Depression
- Thromboembolism
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| NSAIDs | Moderate | Increased risk of fluid retention |
| Anticoagulants | Moderate | Increased bleeding risk |
| Corticosteroids | Moderate | Increased risk of hyperglycemia |
๐จ Major Interactions
- Estrogen-containing medications
- Progestins
- Gonadotropins
โก Moderate Interactions
- Antidiabetic agents
- Corticosteroids
- Anticoagulants
โน๏ธ Minor Interactions
- None significant
๐ฝ๏ธ Food Interactions
None known
๐ท Alcohol Interaction
No known interaction
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Pregnancy, lactation, undiagnosed vaginal bleeding, hypersensitivity to GnRH agonists
๐ Monitoring Parameters
Hormone levels (LH, FSH, estradiol/testosterone), bone density, lipid profile, blood glucose
๐คฑ Lactation Safety
Not recommended; may suppress lactation
๐ Overdose Management
Supportive care; no specific antidote
โฐ Missed Dose
Administer as soon as remembered; do not double dose
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for agopride injection
View AllAlternative brands with exact same active ingredient (Leuprolide (1mg/ml)):
-
gynact injectionBharat Serums & Vaccines Ltd โน121.25 51.5% CHEAPER
-
luprorin injectionIntas Pharmaceuticals Ltd โน172.11 31.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.