ageflux olx capsule sr - Uses, Price, Side Effects & Substitutes
What is ageflux olx capsule sr used for?
Ageflux OLX Capsule SR (Levosulpiride + Esomeprazole) is used to treat GASTRO INTESTINAL. It contains Levosulpiride (75mg) + Esomeprazole (40mg), which Levosulpiride: Blocks D2 dopamine receptors in the GI tract, enhancing gastric m. Always consult your doctor before use. Take as prescribed.
- Generic Name: Levosulpiride + Esomeprazole
- Manufacturer: Aegisco Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ ageflux olx capsule sr Uses & Benefits
Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, irritable bowel syndrome with predominant dysmotility
Off-label uses: Diabetic gastroparesis, functional dyspepsia, cyclic vomiting syndrome
๐ Drug Information
| Generic Name(s) | Levosulpiride + Esomeprazole |
| Brand Name | Ageflux OLX Capsule SR |
| Manufacturer | Aegisco Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Levosulpiride: Blocks D2 dopamine receptors in the GI tract, enhancing gastric motility and emptying; Esomeprazole: Irreversibly inhibits H+/K+ ATPase in gastric parietal cells, reducing gastric acid secretion
Mechanism Steps
๐ก How to Take ageflux olx capsule sr
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of ageflux olx capsule sr
โ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Flatulence
- Dizziness
๐จ Serious Side Effects
- QT prolongation
- Tardive dyskinesia
- Neuroleptic malignant syndrome
- Clostridium difficile infection
- Hypomagnesemia
โ ๏ธ Rare Side Effects
- Gynecomastia
- Galactorrhea
- Interstitial nephritis
- Stevens-Johnson syndrome
- Hepatotoxicity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Clopidogrel | Major | Reduced clopidogrel efficacy due to CYP2C19 inhibition by esomeprazole |
| Methotrexate | Major | Increased methotrexate toxicity due to reduced renal clearance |
| Cilostazol | Major | Increased cilostazol levels and risk of bleeding |
| Ketoconazole | Moderate | Reduced ketoconazole absorption due to increased gastric pH |
| Digoxin | Moderate | Possible increased digoxin levels |
| Warfarin | Minor | Possible increased INR |
๐จ Major Interactions
- Cilostazol
- Clopidogrel
- Methotrexate
- Rilpivirine
- St John's Wort
โก Moderate Interactions
- Diazepam
- Digoxin
- Iron salts
- Ketoconazole
- Tacrolimus
โน๏ธ Minor Interactions
- Caffeine
- Theophylline
- Warfarin
๐ฝ๏ธ Food Interactions
Food may delay absorption of esomeprazole; levosulpiride absorption unaffected
๐ท Alcohol Interaction
Alcohol may worsen GI symptoms and increase risk of side effects
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, GI hemorrhage, mechanical obstruction, perforation, prolactin-dependent tumors, concomitant use with clopidogrel
๐ Monitoring Parameters
Liver function tests, renal function, ECG (QT interval), serum prolactin levels
๐คฑ Lactation Safety
Not recommended; both drugs excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; no specific antidote; dialysis may remove levosulpiride
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double dose