af-ter lotion allopathy (Terbinafine (1% w/v)) - Uses in Hindi, Side Effects, Substitutes & Price in India
af-ter lotion allopathy (Terbinafine (1% w/v)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Palsons Derma. Contains Terbinafine (1% w/v).

af-ter lotion - Uses, Price, Side Effects & Substitutes

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Terbinafine (1% w/v) (Click to see all medicines with same salt)
🏭 Palsons Derma 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 22, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is af-ter lotion used for?

Af-ter Lotion (Terbinafine) is used to treat Topical treatment of dermatophyte infections (tinea pedis. It contains Terbinafine (1% w/v), which Inhibits squalene epoxidase, blocking ergosterol synthesis in fungal cell membra. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Terbinafine
  • Manufacturer: Palsons Derma
  • Medicine Form: Allopathy
  • Pregnancy Category: B

🇮🇳 af-ter lotion के बारे में संक्षिप्त जानकारी (Hindi Summary)

af-ter lotion का उपयोग मुख्य रूप से anti infectives और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Terbinafine (1% w/v) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

📋 Drug Information

Generic Name(s)Terbinafine
Brand NameAf-ter Lotion
ManufacturerPalsons Derma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassFungal ergosterol synthesis inhibitor
Route of AdministrationTopical
StorageStore at 20-25°C (68-77°F); protect from light
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionApproximately 70-80% absorbed through skin; systemic absorption minimal (<5%)
DistributionDistributes into stratum corneum, epidermis, dermis, and hair follicles; high affinity for keratin
Protein Binding>99% bound to plasma proteins
MetabolismHepatic via CYP450 enzymes (CYP2C9, CYP1A2, CYP3A4) to inactive metabolites
Half-Life11-17 hours (topical); 200-400 hours from skin
ExcretionPrimarily renal (70-80% as metabolites); some fecal
BioavailabilitySystemic bioavailability <5% after topical application
Onset of ActionWithin 1-2 weeks of regular application
Peak Plasma TimeNot applicable (minimal systemic absorption)
Duration of ActionSustained for several days after application

Pharmacodynamics

Mechanism of ActionInhibits squalene epoxidase, blocking ergosterol synthesis in fungal cell membrane
Target ReceptorSqualene epoxidase (fungal enzyme)
Pharmacodynamic EffectsFungicidal against dermatophytes; fungistatic against some yeasts

💡 How and when to take af-ter lotion?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 20-25°C (68-77°F); protect from light

⚙️ How af-ter lotion Works

Inhibits squalene epoxidase, blocking ergosterol synthesis in fungal cell membrane

1 Terbinafine enters fungal cell
⬇️
2 Binds to squalene epoxidase
⬇️
3 Inhibits conversion of squalene to lanosterol
⬇️
4 Depletes ergosterol in cell membrane
⬇️
5 Accumulates toxic squalene
⬇️
6 Disrupts membrane integrity and function
⬇️
7 Leads to fungal cell death

💊 af-ter lotion Uses in Hindi (Ke Fayde), Benefits & Indications

Topical treatment of dermatophyte infections (tinea pedis, tinea cruris, tinea corporis)

Off-label uses: Tinea versicolor, Cutaneous candidiasis

⚠️ What are the side effects of af-ter lotion?

✅ Common Side Effects

  • Application site irritation
  • Redness
  • Itching
  • Burning

🚨 Serious Side Effects

  • Severe allergic reaction
  • Angioedema
  • Bullous dermatitis

⚠️ Rare Side Effects

  • Contact dermatitis
  • Urticaria

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased INR and bleeding risk
Cimetidine Major Decreased terbinafine clearance
Rifampin Major Increased terbinafine clearance
Cyclosporine Moderate Decreased cyclosporine levels
Oral contraceptives Moderate Possible menstrual irregularities
Theophylline Moderate Increased theophylline levels
Caffeine Minor Decreased caffeine clearance
Alcohol Minor No significant effect

🚨 Major Interactions

  • Warfarin
  • Cimetidine
  • Rifampin

⚡ Moderate Interactions

  • Cyclosporine
  • Oral contraceptives
  • Theophylline

ℹ️ Minor Interactions

  • Caffeine
  • Alcohol

🍽️ Food Interactions

No significant food interactions

🍷 Alcohol Interaction

No known interaction

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to terbinafine or any component

📊 Monitoring Parameters

Clinical improvement; signs of irritation or allergic reaction

🤱 Lactation Safety

Excreted in breast milk; use with caution

💊 Overdose Management

Unlikely with topical use; if ingested, symptomatic and supportive care

⏰ Missed Dose

Apply as soon as remembered; skip if almost time for next dose

🛑 Myths vs. Facts about af-ter lotion

  • Myth: Generic substitutes of af-ter lotion are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Terbinafine (1% w/v)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of af-ter lotion can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

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