exclusivederm neo ointment - Terbinafine (1% w/w) + Clobetasol (0.05% w/v) medicine

Exclusivederm Neo Ointment: A Comprehensive Guide

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🏭 May and Baker Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe burning, itching, or rash at the application site
  • Signs of skin thinning (shiny, fragile skin)
  • New stretch marks or visible blood vessels
  • Symptoms of high blood sugar (increased thirst, frequent urination)
  • Signs of allergic reaction (swelling of face, lips, throat, difficulty breathing)
  • No improvement after 1 week of use
  • Infection spreads or worsens

If experiencing severe symptoms, call emergency services immediately.

What is exclusivederm neo ointment used for?

This medicine is a topical ointment combining terbinafine (an antifungal) and clobetasol (a potent corticosteroid). It is used to treat fungal skin infections that are accompanied by inflammation, such as ringworm with redness and itching. Apply a thin film to the affected area as prescribed, usually once or twice daily, for up to 2 weeks.

  • Generic Name: Terbinafine (1% w/w) + Clobetasol (0.05% w/v)
  • Manufacturer: May and Baker Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 exclusivederm neo ointment के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल ऑइंटमेंट है जिसमें टर्बिनाफाइन और क्लोबेटासोल होते हैं। यह फंगल संक्रमण के साथ-साथ सूजन, खुजली और लालिमा का इलाज करने के लिए इस्तेमाल की जाती है। इसे डॉक्टर के निर्देशानुसार ही लगाएं।

साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर जलन, खुजली या लालिमा शामिल हैं। लंबे समय तक उपयोग से त्वचा पतली हो सकती है और अन्य गंभीर समस्याएं हो सकती हैं। किसी भी असामान्य लक्षण पर डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को केवल त्वचा पर ही लगाएं। आंखों, मुंह और अन्य श्लेष्मा झिल्ली से बचें। डॉक्टर के बताए समय से ज्यादा इस्तेमाल न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 exclusivederm neo ointment Uses & Benefits

[{"condition":"Tinea corporis (ringworm) with inflammation","description":"Used to treat ringworm infections of the body that are accompanied by significant redness, itching, and swelling.","evidence":"Well-established"},{"condition":"Tinea cruris (jock itch) with inflammation","description":"Effective for fungal infections of the groin area when there is marked inflammatory component.","evidence":"Well-established"},{"condition":"Tinea pedis (athlete's foot) with inflammation","description":"Treats fungal infections of the feet, especially when there is severe itching and inflammation.","evidence":"Well-established"},{"condition":"Cutaneous candidiasis with inflammation","description":"Used for skin yeast infections that have a significant inflammatory component.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Seborrheic dermatitis with suspected fungal component","description":"Sometimes used when fungal elements are suspected, but not a standard first-line treatment.","evidence":"Limited"}]

Primary treatment for: Fungal skin infections with inflammation

Also treats: Tinea corporis, Tinea cruris, Tinea pedis, Cutaneous candidiasis

📋 Drug Information

Generic Name(s)Terbinafine (1% w/w) + Clobetasol (0.05% w/v)
Brand Nameexclusivederm neo ointment
ManufacturerMay and Baker Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore below 30°C in a dry place. Do not freeze. Keep the tube tightly closed when not in use.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin film only to the affected area and avoid normal skin.
2
Do not use for more than 2 weeks without medical review.
3
Avoid using on the face, groin, or underarms unless specifically prescribed.
4
Wash your hands after application unless treating your hands.
5
Do not cover the treated area with tight bandages or dressings.
6
If the condition worsens or does not improve after 1 week, consult your doctor.
7
Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Itchy, red, ring-shaped rash
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTerbinafine is poorly absorbed through intact skin; systemic absorption is minimal. Clobetasol can be absorbed through the skin, especially when applied to large areas, under occlusion, or to inflamed skin. Absorption increases with duration of use.
DistributionNot established from the available information.
Protein BindingTerbinafine is highly protein-bound (>99%) in plasma. Clobetasol is also extensively protein-bound.
MetabolismTerbinafine is extensively metabolized in the liver by cytochrome P450 enzymes. Clobetasol is metabolized primarily in the liver.
Half-LifeTerbinafine elimination half-life is approximately 200-400 hours from tissues. Clobetasol plasma half-life is about 3 hours.
ExcretionTerbinafine metabolites are excreted mainly in urine. Clobetasol metabolites are excreted in urine and bile.
BioavailabilityNot established from the available information for topical application.
Onset of ActionAnti-inflammatory effects of clobetasol may begin within hours; antifungal effects of terbinafine take several days to become noticeable.
Peak Plasma TimeNot established from the available information.
Duration of ActionAnti-inflammatory effect lasts for several hours after application; antifungal effect persists with regular use.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Terbinafine is an allylamine antifungal that inhibits the enzyme squalene epoxidase, leading to a deficiency of ergosterol, a vital component of the fungal cell membrane, and accumulation of squalene, which is toxic to the fungus. This results in fungal cell death. Clobetasol is a synthetic corticosteroid that binds to glucocorticoid receptors in the skin, leading to suppression of inflammatory mediators such as cytokines and leukocytes. This reduces redness, itching, and swelling. The combination provides both antifungal and anti-inflammatory effects.

Mechanism Steps

1
Terbinafine inhibits squalene epoxidase: Terbinafine binds to and inhibits the fungal enzyme squalene epoxidase, blocking the conversion of squalene to lanosterol, a precursor of ergosterol.
2
Ergosterol deficiency and squalene accumulation: The lack of ergosterol weakens the fungal cell membrane, while accumulated squalene is toxic, leading to fungal cell death.
3
Clobetasol binds to glucocorticoid receptors: Clobetasol diffuses into cells and binds to cytoplasmic glucocorticoid receptors, forming a complex that translocates to the nucleus.
4
Suppression of inflammatory genes: The complex inhibits transcription of pro-inflammatory genes and induces anti-inflammatory proteins, reducing inflammation and itching.

💡 How to Take exclusivederm neo ointment

Strength: Ointment containing terbinafine 1% w/w and clobetasol 0.05% w/v.

1Wash your hands thoroughly before and after applying the ointment.
2Clean and dry the affected skin area gently.
3Apply a thin film of the ointment to the affected area and gently rub it in.
4Do not cover the area with bandages or dressings unless instructed by your doctor.
5Avoid contact with eyes, mouth, and other mucous membranes.
6Use the ointment exactly as prescribed, and do not use it for longer than recommended.

Dosage Information

Adult DosageApply a thin film to the affected area once or twice daily, or as directed by your doctor. The duration of treatment depends on the condition and your response. Typically, treatment should not exceed 2 weeks without medical review. Dose must be individualized by a qualified clinician based on indication, age, and severity of the condition.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to skin thinning and systemic effects. Use with caution and for the shortest duration possible.
Renal ImpairmentNo dose adjustment is typically required for topical use, as systemic absorption is minimal. However, consult a doctor if you have severe kidney disease.
Hepatic ImpairmentNo dose adjustment is typically required for topical use, as systemic absorption is minimal. However, consult a doctor if you have severe liver disease.
Maximum Daily DoseNot established from the available information. Use only as prescribed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of exclusivederm neo ointment

✅ Common Side Effects

Application site burning or stinging (Common (1-10%))
Usually resolves with continued use. If severe, consult your doctor.
Itching at application site (Common (1-10%))
May be due to the condition or the medicine. Consult if persistent.
Redness or rash (Common (1-10%))
Monitor. If worsens, stop and consult doctor.

🚨 Serious Side Effects

Skin atrophy (thinning) (Uncommon (0.1-1%))
Stop use and consult doctor if skin becomes thin, shiny, or fragile.
Stretch marks (striae) (Uncommon (0.1-1%))
Report to doctor if new stretch marks appear.
Telangiectasia (visible blood vessels) (Uncommon (0.1-1%))
Consult doctor if small blood vessels become visible on treated skin.
Systemic corticosteroid effects (e.g., high blood sugar, high blood pressure) (Rare (<0.1%))
Seek medical attention if you experience symptoms like increased thirst, frequent urination, or headaches.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate emergency care if you have difficulty breathing, swelling of face, lips, or throat, or severe rash.

⚠️ Rare Side Effects

Adrenal suppression
Consult doctor if you experience fatigue, weakness, or weight loss.
Cushing's syndrome
Report rapid weight gain, moon face, or easy bruising to doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other topical corticosteroids Major
CYP2D6 inhibitors Moderate
CYP3A4 inhibitors Moderate

🚨 Major Interactions

  • Other topical corticosteroids
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

🍷 Alcohol Interaction

No known interaction with alcohol when used topically. However, alcohol may worsen certain skin conditions.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to terbinafine, clobetasol, or any component of the formulation","Untreated bacterial, viral, or parasitic skin infections","Acne vulgaris, rosacea, perioral dermatitis","Use on the face, groin, or axillae unless directed by a doctor","Children under 12 years of age (unless specifically prescribed)"]

⚠️ Warnings & Precautions

["For external use only. Do not ingest.","Avoid contact with eyes, lips, and mucous membranes.","Do not use on large areas or for prolonged periods without medical supervision.","Do not use under occlusive dressings unless instructed.","May cause skin thinning; use with caution on thin skin areas.","If irritation or sensitization occurs, discontinue use and consult a doctor.","Do not use for more than 2 weeks without medical review.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether terbinafine or clobetasol are excreted in human milk after topical application. Caution is advised when used by breastfeeding mothers. Avoid application to the breast area to prevent infant exposure.

💊 Overdose Management

Topical overdose is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of systemic corticosteroid overdose may include nausea, vomiting, and electrolyte imbalance. Treatment is supportive.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Use this medicine only on the skin area prescribed by your doctor. Wash your hands thoroughly before and after applying, unless the hands are the treated area. Apply a thin film and gently rub it in. Do not cover the treated area with bandages or dressings unless instructed, as this can increase absorption and side effects. Avoid contact with eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not use this medicine for longer than prescribed, as prolonged use increases the risk of skin thinning and systemic effects. Do not use on children under 12 years unless specifically directed by a doctor. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine to treat any other skin condition without consulting a doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to skin thinning and systemic effects from corticosteroids. Use with caution, for the shortest duration, and monitor for side effects.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The benefits must outweigh the risks.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine on surgical wounds or nearby skin. It may interfere with wound healing.

🦷 Dental Procedures

No specific considerations for dental procedures. Inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid sharing towels, clothing, or bedding to prevent spread.
😴
Wear loose-fitting cotton clothing to reduce irritation.
💧
Avoid scratching the affected area to prevent secondary infection.
🧘
Maintain good hygiene to prevent reinfection.

🏋️ Exercise Considerations

No specific exercise restrictions. However, avoid activities that cause excessive sweating or friction on the treated area until healed.

🥗 Diet Recommendations

Eat a balanced diet rich in vitamins and minerals to support skin health.
Stay well hydrated.
Limit sugary and processed foods, which may promote fungal growth.

💼 Impact on Daily Work & Life

This medicine is applied topically and does not affect your ability to drive or operate machinery. You can continue your normal daily activities, but avoid swimming or activities that may wash off the ointment immediately after application.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your symptoms worsen, if you develop severe irritation, or if there is no improvement after 1 week. Do not stop abruptly if you have been using it for a long time; consult your doctor for a tapering plan.

📅 Long-Term Use Effects

Prolonged use of this medicine can lead to skin thinning, stretch marks, visible blood vessels, and increased hair growth. Systemic absorption of clobetasol can cause high blood sugar, high blood pressure, and adrenal suppression. Use only for the shortest duration necessary and under medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical antifungals alone

For mild fungal infections without significant inflammation, a plain antifungal cream may be sufficient.

Evidence: Well-established
Oral antifungals

For extensive or resistant infections, oral terbinafine may be prescribed.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription in case of customs checks. Store at room temperature and protect from extreme heat or cold. No time zone adjustments are needed for topical use.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with itchy, red ring-shaped rash on his arm
He was prescribed this medicine twice daily for 2 weeks. Within 3 days, the itching reduced significantly, and the rash started to fade. He was advised not to stop early and to complete the full course. He experienced mild burning on the first day, which resolved.
💡 Lesson: Complete the full course even if symptoms improve, to prevent recurrence.
👤 A 50-year-old woman with jock itch and severe inflammation
She used this medicine for 10 days as directed. The inflammation and itching subsided quickly. She was cautioned not to use it for more than 2 weeks due to the steroid component. She followed up with her doctor, who confirmed the infection had cleared.
💡 Lesson: Short-term use under medical supervision is safe and effective.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may notice relief from itching and redness within a few days. However, the fungal infection may take 1-2 weeks to clear completely. Complete the full course as prescribed.

Q: Can I use this medicine on my face?

A: No, unless specifically directed by your doctor. The face is more sensitive to steroids and may develop side effects like thinning.

Q: Is this medicine safe for children?

A: It is not recommended for children under 12 years unless prescribed by a doctor. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How long can I use this medicine?
  • Is it safe for children?
  • What if I miss a dose?
  • Can I use it with other skin products?
  • Does it interact with my other medicines?

🛑 Myths vs. Facts

  • Myth: This medicine can cure any skin rash.
    Fact: It is only effective for fungal infections with inflammation. It can worsen other skin conditions.
  • Myth: More ointment means faster healing.
    Fact: Using more than prescribed increases the risk of side effects without improving efficacy.
  • Myth: It is safe to use for months.
    Fact: Prolonged use can cause skin thinning and systemic effects. Use only as directed.

🔄 Alternative Options

Generic Alternatives

  • Terbinafine 1% + Clobetasol 0.05% ointment (generic versions)

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Terbinafine 1% + Clobetasol 0.05%","potency":"Very potent steroid","indication":"Fungal infections with inflammation"},{"medicine":"Clotrimazole + Betamethasone","composition":"Clotrimazole 1% + Betamethasone 0.05%","potency":"Potent steroid","indication":"Fungal infections with inflammation"}]

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