adyom ls 75mg/40mg capsule - Levosulpiride (75mg) + Esomeprazole (40mg) medicine

adyom ls 75mg/40mg capsule

4.4 (12 reviews)
๐Ÿญ Hauz Pharma Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is adyom ls 75mg/40mg capsule used for?

Ageflux OLX Capsule SR (Levosulpiride + Esomeprazole) is used to treat GASTRO INTESTINAL. It contains Levosulpiride (75mg) + Esomeprazole (40mg), which Levosulpiride: Blocks D2 dopamine receptors in the GI tract, enhancing gastric m. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Levosulpiride + Esomeprazole
  • Manufacturer: Hauz Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š adyom ls 75mg/40mg capsule Uses & Benefits

Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, irritable bowel syndrome with predominant dysmotility

Off-label uses: Diabetic gastroparesis, functional dyspepsia, cyclic vomiting syndrome

๐Ÿ“‹ Drug Information

Generic Name(s)Levosulpiride + Esomeprazole
Brand NameAgeflux OLX Capsule SR
ManufacturerHauz Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassProkinetic agent + Proton pump inhibitor
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture and light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionLevosulpiride: Well absorbed orally; Esomeprazole: Rapidly absorbed, peak plasma concentration in 1-2 hours
DistributionLevosulpiride: Widely distributed, crosses blood-brain barrier; Esomeprazole: High plasma protein binding, distributed to gastric parietal cells
Protein BindingLevosulpiride: ~40%; Esomeprazole: ~97%
MetabolismLevosulpiride: Hepatic (CYP3A4); Esomeprazole: Hepatic (CYP2C19, CYP3A4)
Half-LifeLevosulpiride: 8-10 hours; Esomeprazole: 1-1.5 hours
ExcretionLevosulpiride: Renal (70-90% unchanged); Esomeprazole: Renal (80% as metabolites)
BioavailabilityLevosulpiride: ~30%; Esomeprazole: ~64% (after repeated dosing)
Onset of ActionLevosulpiride: 30-60 minutes; Esomeprazole: 1 hour
Peak Plasma TimeLevosulpiride: 1-3 hours; Esomeprazole: 1-2 hours
Duration of ActionLevosulpiride: 8-12 hours; Esomeprazole: Up to 24 hours

How It Works

Levosulpiride: Blocks D2 dopamine receptors in the GI tract, enhancing gastric motility and emptying; Esomeprazole: Irreversibly inhibits H+/K+ ATPase in gastric parietal cells, reducing gastric acid secretion

Mechanism Steps

1Levosulpiride blocks D2 dopamine receptors in the GI tract, increasing acetylcholine release and enhancing gastric motility.
2Esomeprazole accumulates in the acidic environment of gastric parietal cells.
3Esomeprazole is converted to its active form, which binds covalently to H+/K+ ATPase.

๐Ÿ’ก How to Take adyom ls 75mg/40mg capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of adyom ls 75mg/40mg capsule

โœ… Common Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Flatulence
  • Dizziness

๐Ÿšจ Serious Side Effects

  • QT prolongation
  • Tardive dyskinesia
  • Neuroleptic malignant syndrome
  • Clostridium difficile infection
  • Hypomagnesemia

โš ๏ธ Rare Side Effects

  • Gynecomastia
  • Galactorrhea
  • Interstitial nephritis
  • Stevens-Johnson syndrome
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Clopidogrel Major Reduced clopidogrel efficacy due to CYP2C19 inhibition by esomeprazole
Methotrexate Major Increased methotrexate toxicity due to reduced renal clearance
Cilostazol Major Increased cilostazol levels and risk of bleeding
Ketoconazole Moderate Reduced ketoconazole absorption due to increased gastric pH
Digoxin Moderate Possible increased digoxin levels
Warfarin Minor Possible increased INR

๐Ÿšจ Major Interactions

  • Cilostazol
  • Clopidogrel
  • Methotrexate
  • Rilpivirine
  • St John's Wort

โšก Moderate Interactions

  • Diazepam
  • Digoxin
  • Iron salts
  • Ketoconazole
  • Tacrolimus

โ„น๏ธ Minor Interactions

  • Caffeine
  • Theophylline
  • Warfarin

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption of esomeprazole; levosulpiride absorption unaffected

๐Ÿท Alcohol Interaction

Alcohol may worsen GI symptoms and increase risk of side effects

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, GI hemorrhage, mechanical obstruction, perforation, prolactin-dependent tumors, concomitant use with clopidogrel

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, ECG (QT interval), serum prolactin levels

๐Ÿคฑ Lactation Safety

Not recommended; both drugs excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; no specific antidote; dialysis may remove levosulpiride

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

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