Avigel O Oral Suspension: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or stool
- Severe abdominal pain
- Difficulty breathing or swelling of face, lips, or throat
- Chest pain
- Severe constipation with inability to pass stool
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is adunile suspension used for?
This medicine is a combination of sucralfate and oxetacaine used to treat gastritis, GERD, and peptic ulcers. It works by forming a protective barrier over the stomach lining and numbing the area to relieve pain.
- Generic Name: Sucralfate + Oxetacaine
- Manufacturer: Assure Lifescience Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 adunile suspension के बारे में (Hindi Summary)
उपयोग: यह दवा सुक्राल्फेट और ऑक्सेटाकेन का संयोजन है, जिसका उपयोग गैस्ट्रिटिस, एसिड रिफ्लक्स, और पेप्टिक अल्सर के इलाज के लिए किया जाता है। यह पेट की परत पर एक सुरक्षात्मक परत बनाकर और दर्द को सुन्न करके राहत देती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में कब्ज, मुँह सूखना, मतली और चक्कर आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी प्रतिक्रियाएँ हो सकती हैं।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार लें। उपयोग से पहले बोतल को अच्छी तरह हिलाएँ। अन्य दवाओं के साथ लेने से पहले 2 घंटे का अंतराल रखें। गर्भवती या स्तनपान कराने वाली महिलाएँ डॉक्टर से सलाह लें।
💊 adunile suspension Uses & Benefits
[{"condition":"Gastritis","description":"Relieves inflammation of the stomach lining and associated pain.","evidence":"Well-established"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces symptoms of acid reflux and heartburn by protecting the esophagus.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Helps heal ulcers by forming a protective barrier over the ulcer surface.","evidence":"Well-established"},{"condition":"Esophagitis","description":"Provides relief from pain and irritation in the esophagus.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Mucositis due to chemotherapy or radiation","description":"Sometimes used to soothe oral and gastrointestinal mucositis.","evidence":"Limited"},{"condition":"Stress ulcer prophylaxis","description":"Occasionally used in critically ill patients to prevent stress ulcers.","evidence":"Limited"}]
Primary treatment for: Gastritis
Also treats: Gastroesophageal reflux disease, Peptic ulcer disease, Esophagitis
📋 Drug Information
| Generic Name(s) | Sucralfate + Oxetacaine |
| Brand Name | Axid O Suspension |
| Manufacturer | Assure Lifescience Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Gastrointestinal protective agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Sucralfate works locally by forming a viscous paste that adheres to ulcerated or inflamed mucosa, creating a physical barrier against acid, pepsin, and bile salts. It also inhibits pepsin activity and binds bile acids. Oxetacaine is a local anesthetic that numbs the mucosal surface, providing rapid relief from pain and discomfort.
Mechanism Steps
💡 How to Take adunile suspension
Strength: Each 10 mL of suspension contains sucralfate 1000 mg and oxetacaine 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 10 mL of the suspension taken orally four times a day, preferably on an empty stomach, or as directed by your physician. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal function. Consult your doctor. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor. |
| Hepatic Impairment | No specific dose adjustment recommended for hepatic impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 40 mL of the suspension (4000 mg sucralfate and 40 mg oxetacaine). Do not exceed without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of adunile suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ciprofloxacin | Major | |
| Tetracycline | Major | |
| Levothyroxine | Major | |
| Digoxin | Moderate | |
| Warfarin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Fluoroquinolone antibiotics (e.g., ciprofloxacin, levofloxacin)
- Tetracycline antibiotics
- Levothyroxine
⚡ Moderate Interactions
- Digoxin
- Warfarin
🍷 Alcohol Interaction
Alcohol may increase stomach irritation and worsen the condition being treated. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to sucralfate or oxetacaine","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Use with caution in patients with renal impairment.","Avoid taking within 2 hours of other medications.","Do not exceed prescribed dose.","May cause constipation; increase fluid and fiber intake.","Not recommended for long-term use without medical supervision."]
🤱 Lactation Safety
It is not known whether sucralfate or oxetacaine pass into breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose is unlikely to cause serious effects due to poor absorption. However, if large amounts are ingested, seek medical attention. Symptoms may include gastrointestinal discomfort. Treatment is supportive.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Shake the bottle well before each use to ensure the medicine is mixed properly. Measure the dose using the provided measuring cup or spoon. Do not take this medicine within two hours of taking other medications, as sucralfate can reduce their absorption. Avoid alcohol while taking this medicine, as it may worsen stomach irritation. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to constipation and renal effects. Dose adjustment may be needed based on kidney function.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy. The safety of this medicine during pregnancy is not well established.
🏥 Post-Surgery Considerations
Consult your surgeon before taking this medicine after surgery, as it may interact with other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may affect absorption of other medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe. Avoid vigorous exercise immediately after meals to prevent reflux.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery if you feel dizzy. Otherwise, it should not significantly impact daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine should be monitored by a doctor. Prolonged use may lead to constipation or aluminum accumulation in patients with kidney disease. Regular follow-up is recommended.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Avoiding trigger foods can reduce symptoms.
Evidence: Well-establishedStress reduction techniques can help manage symptoms.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions reported. Consult your doctor for routine vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Oxetacaine provides pain relief within minutes, while sucralfate starts protecting the stomach lining immediately. Full healing may take several days to weeks.
A: It is best taken on an empty stomach, at least 1 hour before or 2 hours after meals, to allow the protective barrier to form.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for adunile suspension
View AllAlternative brands with exact same active ingredient:
-
vrisucra o oral suspensionVrinda Life ₹64.97 59.4% CHEAPER
-
Focri-O SyrupForgo Pharmaceuticals Pvt Ltd ₹73.13 54.3% CHEAPER
-
oxicane syrupScorsis Laboratories ₹78.52 50.9% CHEAPER
-
sucracan o syrupCanopy Healthcare Pvt Ltd ₹83.44 47.9% CHEAPER
-
dufacain syrupAfive Pharma ₹91.88 42.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken with food.
Fact: It should be taken on an empty stomach for best effect. - Myth: It is safe to take indefinitely.
Fact: Long-term use should be monitored by a doctor.
🔄 Alternative Options
Generic Alternatives
- Sucralfate + Oxetacaine suspension
Brand Alternatives
- Avigel O
- Sucrafil O
- Ulgel
- Oraflox