adsure gel - Adapalene (0.1% w/w) medicine

Adsure Gel (Adapalene 0.1% w/w) - Uses, Price, Side Effects

4.6 (9 reviews)
๐Ÿญ Assure Lifescience Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is adsure gel used for?

Adsure Gel contains Adapalene 0.1% w/w, a retinoid used to treat acne vulgaris. It works by normalizing skin cell turnover and reducing inflammation, preventing clogged pores and formation of new acne lesions. Apply a thin layer once daily at night to clean, dry skin. Results may be seen in 8-12 weeks.

  • Generic Name: Adapalene
  • Manufacturer: Assure Lifescience Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š adsure gel Uses & Benefits

Acne vulgaris (comedonal, inflammatory, and mixed acne).

Off-label uses: Photoaging, Keratosis pilaris, Melasma

๐Ÿ“‹ Drug Information

Generic Name(s)Adapalene
Brand NameAdaferin Gel
ManufacturerAssure Lifescience Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassRetinoids- Third generation
Route of AdministrationTopical
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and heat.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionApproximately 2.5% of topically applied adapalene is absorbed through the skin.
DistributionDistributed into skin layers; systemic distribution is minimal due to low absorption.
Protein Binding>99% bound to plasma proteins.
MetabolismMetabolized primarily by cytochrome P450 enzymes, mainly CYP2C9 and CYP3A4.
Half-LifeApproximately 7-10 hours (topical); systemic half-life not well defined.
ExcretionPrimarily excreted in feces (biliary) and to a lesser extent in urine.
BioavailabilityLow systemic bioavailability (<5%) due to minimal percutaneous absorption.
Onset of ActionClinical improvement may be seen within 2-4 weeks of regular use.
Peak Plasma TimeNot applicable for topical use; systemic levels are negligible.
Duration of ActionSustained effect with once-daily application; continuous use required for maintenance.

How It Works

Binds to retinoic acid receptors (RARs), modulating gene expression to normalize follicular keratinization and reduce inflammation.

Mechanism Steps

1Binds to retinoic acid receptors (RAR-ฮฒ and RAR-ฮณ) in keratinocytes
2Modulates gene expression involved in cell differentiation and proliferation
3Normalizes follicular keratinization, reducing microcomedone formation

๐Ÿ’ก How to Take adsure gel

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โŒ ๐ŸŒ™ Night โœ…

โš ๏ธ Side Effects of adsure gel

โœ… Common Side Effects

  • Skin dryness
  • Erythema
  • Peeling
  • Burning sensation
  • Pruritus

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction
  • Angioedema
  • Stevens-Johnson syndrome (rare)

โš ๏ธ Rare Side Effects

  • Hyperpigmentation
  • Hypopigmentation
  • Photosensitivity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Benzoyl Peroxide Moderate Increased skin irritation
Tetracyclines Minor Possible photosensitivity

๐Ÿšจ Major Interactions

  • Other topical retinoids
  • Benzoyl peroxide (concomitant use may cause irritation)

โšก Moderate Interactions

  • Topical corticosteroids
  • Topical antibiotics (e.g., clindamycin)

โ„น๏ธ Minor Interactions

  • Sunscreens
  • Cosmetics with drying agents

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction; however, alcohol may increase skin dryness.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to adapalene or any component; pregnancy (category C); eczema; sunburn.

๐Ÿ“Š Monitoring Parameters

Skin irritation, dryness, peeling; therapeutic response (reduction in acne lesions).

๐Ÿคฑ Lactation Safety

Not recommended; unknown if excreted in breast milk.

๐Ÿ’Š Overdose Management

Topical overdose unlikely; if ingested, treat symptomatically.

โฐ Missed Dose

Apply as soon as remembered; if close to next dose, skip missed dose. Do not double.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for adsure gel

View All

Alternative brands with exact same active ingredient (Adapalene (0.1% w/w)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

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