Adrosal 10mg Injection - Uses, Price, Side Effects
What is adrosal 10mg injection used for?
Adrosal 10mg Injection contains Doxorubicin, a chemotherapy drug used to treat various cancers including breast, ovarian, bladder, and lung cancers. It works by interfering with the growth of cancer cells, slowing or stopping their spread.
- Generic Name: Doxorubicin
- Manufacturer: Vhb Life Sciences Inc
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ adrosal 10mg injection Uses & Benefits
Breast cancer, ovarian cancer, bladder cancer, thyroid cancer, gastric cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma, multiple myeloma, sarcoma, acute lymphoblastic leukemia, acute myeloid leukemia.
Off-label uses: Hepatocellular carcinoma, endometrial cancer, Wilms tumor, Ewing sarcoma.
๐ Drug Information
| Generic Name(s) | Doxorubicin |
| Brand Name | Adriamycin |
| Manufacturer | Vhb Life Sciences Inc |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkaloids-cytotoxic agents |
| Route of Administration | Intravenous (IV) only; avoid intramuscular or subcutaneous. |
| Storage | Store at 2-8ยฐC. Protect from light. Reconstituted solution stable for 24 hours at room temperature. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Intercalates between DNA base pairs, inhibits topoisomerase II, and generates free radicals leading to DNA damage and cell death.
Mechanism Steps
๐ก How to Take adrosal 10mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of adrosal 10mg injection
โ Common Side Effects
- Nausea
- vomiting
- alopecia
- myelosuppression
- mucositis
- stomatitis
- red urine
๐จ Serious Side Effects
- Cardiomyopathy
- congestive heart failure
- severe myelosuppression
- secondary leukemia
- tumor lysis syndrome
- extravasation necrosis
โ ๏ธ Rare Side Effects
- Hemolytic uremic syndrome
- pulmonary fibrosis
- hepatic veno-occlusive disease
- anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Paclitaxel | Moderate | Increased cardiotoxicity |
| Cyclophosphamide | Moderate | Increased cardiotoxicity |
๐จ Major Interactions
- Cyclophosphamide
- Trastuzumab
- Paclitaxel
- Radiation therapy
โก Moderate Interactions
- Verapamil
- Dexrazoxane
- Phenobarbital
โน๏ธ Minor Interactions
- Digoxin
- Heparin
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
Avoid alcohol due to potential hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Severe hepatic impairment, severe myelosuppression, pre-existing cardiomyopathy, hypersensitivity, pregnancy.
๐ Monitoring Parameters
CBC with differential, liver function tests, cardiac function (LVEF), renal function, uric acid levels.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Supportive care; severe myelosuppression may require G-CSF and antibiotics. Dexrazoxane may be used for extravasation or cardiotoxicity.
โฐ Missed Dose
Do not double dose. Contact physician for rescheduling.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for adrosal 10mg injection
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Medical Note: Always consult your doctor before switching medications.