Lippod 20mg Injection (liposomal Doxorubicin): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Chest pain, shortness of breath, or swelling of the legs
- Fever, chills, or sore throat
- Unusual bruising or bleeding
- Pain, burning, redness, or swelling at the injection site
- Flushing, chest tightness, back pain, or difficulty breathing during the infusion
- Yellowing of the eyes or skin, dark urine, or severe abdominal pain
- Sudden swelling of the face, lips, or throat
- Fast or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is adrisome 20mg injection used for?
This medicine is a liposomal form of doxorubicin, an anticancer medicine given into a vein. It is used mainly for advanced ovarian cancer, AIDS-related Kaposi sarcoma, and multiple myeloma. It works by damaging cancer cell DNA and blocking cell division. It must be given only by a cancer specialist because it can cause serious heart, blood, and liver problems.
- Generic Name: Doxorubicin (Liposomal) (20mg)
- Manufacturer: Aureate Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 adrisome 20mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा लिपोसोमल डॉक्सोरूबिसिन का इंजेक्शन है, जिसे कीमोथेरेपी में इस्तेमाल किया जाता है। यह मुख्य रूप से एडवांस्ड ओवेरियन कैंसर, एड्स से जुड़े कपोसी सारकोमा और मल्टीपल मायलोमा के इलाज के लिए दी जाती है। यह कैंसर कोशिकाओं के डीएनए को नुकसान पहुंचाकर उनकी वृद्धि रोकती है। यह दवा सिर्फ कैंसर विशेषज्ञ की देखरेख में अस्पताल या डे-केयर सेंटर में नस के जरिए दी जाती है। इसे घर पर खुद से नहीं लगाया जा सकता। इलाज से पहले और दौरान दिल, लिवर, किडनी और खून की जांच की जाती है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, उल्टी, भूख कम लगना, मुंह में छाले, थकान, खून की कोशिकाओं की कमी और बाल झड़ना शामिल हैं। पेशाब, पसीना या आंसू का रंग नारंगी-लाल हो सकता है, जो सामान्य है और नुकसानदायक नहीं है। गंभीर दुष्प्रभावों में दिल की मांसपेशियों को नुकसान, गंभीर संक्रमण का खतरा, इंजेक्शन की जगह पर नुकसान और गंभीर एलर्जी शामिल हैं। सीने में दर्द, सांस लेने में तकलीफ, तेज बुखार, आसानी से चोट लगना या खून बहना जैसे लक्षण दिखें तो तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा सिर्फ प्रशिक्षित डॉक्टर या नर्स द्वारा अस्पताल में ही दी जानी चाहिए। इलाज से पहले अपने दिल, लिवर, किडनी की बीमारी और किसी भी एलर्जी के बारे में डॉक्टर को जरूर बताएं। इलाज के दौरान खून की जांच नियमित रूप से करवाएं। बुखार, ठंड लगना, गले में दर्द, आसानी से चोट लगना या खून बहना दिखे तो तुरंत डॉक्टर से मिलें। इलाज के दौरान और उसके बाद कुछ समय तक गर्भधारण से बचें और स्तनपान न कराएं। बिना डॉक्टर की सलाह के कोई भी टीका न लगवाएं। इंजेक्शन की जगह पर दर्द, जलन या सूजन हो तो तुरंत बताएं।
💊 adrisome 20mg injection Uses & Benefits
[{"condition":"Advanced ovarian cancer","description":"This medicine is used to treat advanced ovarian cancer, often after platinum-based chemotherapy has been used or when the cancer has come back.","evidence":"Well-established"},{"condition":"AIDS-related Kaposi sarcoma","description":"This medicine is used for Kaposi sarcoma that is widespread or has affected internal organs, especially in people with HIV infection.","evidence":"Well-established"},{"condition":"Multiple myeloma","description":"This medicine is used in combination with other anticancer medicines such as bortezomib for multiple myeloma.","evidence":"Well-established"},{"condition":"Metastatic breast cancer","description":"This medicine may be used in selected patients with metastatic breast cancer when other treatments are not suitable.","evidence":"Established in selected patients"},{"condition":"Other solid tumours and lymphomas","description":"This medicine may be used in other cancers, including some lymphomas and soft tissue sarcomas, when the treating oncologist considers it appropriate.","evidence":"Limited to specialist use"}]
Off-label uses: [{"condition":"Primary central nervous system lymphoma","description":"Sometimes used by specialist teams as part of combination treatment for lymphoma affecting the brain or spinal cord.","evidence":"Limited"},{"condition":"Hepatocellular carcinoma","description":"Occasionally used in selected patients with liver cancer as part of a specialist treatment plan.","evidence":"Limited"}]
Primary treatment for: Advanced ovarian cancer
Also treats: AIDS-related Kaposi sarcoma, Multiple myeloma, Metastatic breast cancer, Selected lymphomas and soft tissue sarcomas
📋 Drug Information
| Generic Name(s) | Doxorubicin (Liposomal) (20mg) |
| Brand Name | adrisome 20mg injection |
| Manufacturer | Aureate Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkaloids-cytotoxic agents |
| Route of Administration | Parenteral |
| Storage | Store this medicine in a refrigerator at 2°C to 8°C. Do not freeze. Keep it in its original carton to protect it from light. Do not use if the solution is discoloured or contains particles. Follow the storage instructions on the label and ask your pharmacist if you are unsure. |
| Shelf Life | The shelf life of this medicine is not established from the available information. Always check the expiry date on the label and do not use it after that date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine contains doxorubicin, which is an anthracycline anticancer antibiotic. Once inside cancer cells, doxorubicin intercalates between the base pairs of DNA and also inhibits topoisomerase II, an enzyme needed for DNA replication and repair. It also generates free radicals that damage DNA and cell membranes. These actions together stop cancer cells from dividing and lead to cell death. The liposomal coating helps the medicine stay in the bloodstream longer and allows it to reach tumour tissue more selectively, which can reduce some of the toxic effects on normal tissues such as the heart.
Mechanism Steps
💡 How to Take adrisome 20mg injection
Strength: This medicine is supplied as a 20 mg strength in a single-use vial for intravenous infusion. The exact volume and concentration are printed on the vial label.
Dosage Information
| Adult Dosage | The dose of this medicine is decided by a qualified cancer specialist and is based on the type of cancer, the patient's body size, previous treatments, and heart, liver, and kidney function. It is given as an intravenous infusion, usually once every three to four weeks, in a hospital or day-care setting. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Patients should never adjust the dose themselves, and the total lifetime dose is limited to reduce the risk of heart damage. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist. |
| Elderly Dosage | Older patients may be more sensitive to the side effects of this medicine, especially heart damage and low blood counts. The treating team will assess heart, liver, and kidney function carefully and may adjust the dose. Close monitoring is important in this age group. |
| Renal Impairment | The exact dose adjustment for patients with kidney disease is not established from the available information. Kidney function should be checked before and during treatment, and the treating team will decide if any adjustment is needed. |
| Hepatic Impairment | Patients with liver disease may need a lower dose because this medicine is cleared mainly by the liver. Liver function tests should be checked before and during treatment, and the dose should be adjusted by the treating team based on the results. |
| Maximum Daily Dose | The maximum dose of this medicine is not a fixed daily amount. It is determined by the treating oncologist based on the type of cancer, body size, and the total lifetime dose limit to protect the heart. Patients should not receive more than the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of adrisome 20mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Live vaccines | Major | |
| Trastuzumab | Major | |
| Other anthracyclines | Major | |
| Phenytoin | Moderate | |
| Phenobarbital | Moderate | |
| Ciclosporin | Moderate | |
| Paracetamol | Minor | |
| Most antibiotics | Minor | |
| Grapefruit juice | Minor | |
| Alcohol | Moderate |
🚨 Major Interactions
- Live vaccines
- Other anthracyclines or trastuzumab
- Cytotoxic chemotherapy that suppresses bone marrow
⚡ Moderate Interactions
- Phenytoin
- Phenobarbital and other enzyme-inducing anticonvulsants
- Ciclosporin
🍷 Alcohol Interaction
Alcohol should be avoided while receiving this medicine because it can worsen nausea, vomiting, liver strain, and tiredness. It may also increase the risk of stomach and mouth irritation. Patients should discuss any alcohol use with their treating team.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe allergic reaction to doxorubicin or any ingredient of this medicine","Severe heart disease or recent heart attack","Very low blood counts from previous treatment or disease","Active serious infection unless the treating team decides otherwise","Pregnancy, unless the treating team has carefully assessed the situation","Breastfeeding"]
⚠️ Warnings & Precautions
["This medicine must be given only by a trained healthcare professional in a setting with emergency equipment.","Heart function should be checked before and during treatment because of the risk of heart muscle damage.","Blood counts should be checked regularly because of the risk of low white cells, red cells, and platelets.","Liver function should be checked before and during treatment, and the dose may need to be adjusted.","Patients should use effective contraception during treatment and for a period afterwards as advised.","Live vaccines should be avoided during treatment.","Any pain, burning, or swelling at the injection site should be reported immediately.","Patients should tell their doctor about all other medicines, supplements, and herbal products they are taking."]
🤱 Lactation Safety
This medicine passes into breast milk and could harm a breastfed baby. Breastfeeding should be stopped before treatment begins and should not be restarted until the treating team says it is safe.
💊 Overdose Management
There is no specific antidote for an overdose of this medicine. Overdose can cause severe bone marrow suppression, heart damage, and liver injury. Treatment is supportive and may include blood transfusions, antibiotics for infection, and close monitoring of heart, liver, and kidney function. Patients who receive too much of this medicine should be managed in a hospital by a specialist team.
⏰ Missed Dose
This medicine is given by a healthcare professional in a hospital or clinic, so a missed dose is unlikely. If an appointment is missed, contact the treating team as soon as possible to reschedule. Do not try to catch up by taking extra doses.
Additional Safety Advice
This medicine must be given only by a trained healthcare professional in a setting where emergency equipment is available. Patients should tell their doctor about any heart problems, previous chemotherapy or radiation, liver disease, or allergies before treatment. Blood tests, including complete blood counts and liver and heart function tests, are usually needed before and during treatment. Because this medicine can lower blood counts, patients should avoid close contact with people who have infections and should report fever, chills, or sore throat immediately. Effective contraception is important during treatment and for a period afterwards, and breastfeeding should be avoided. Patients should not receive live vaccines without medical advice. Any leakage or pain at the injection site during administration must be reported at once.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older patients may be more sensitive to the side effects of this medicine, especially heart damage, low blood counts, and tiredness. Heart, liver, and kidney function should be checked carefully before and during treatment, and the dose may need to be adjusted. Close monitoring and early reporting of symptoms are especially important in this age group.
🤰 Pregnancy Planning (TTC)
This medicine can harm an unborn baby. Women who could become pregnant should use effective contraception during treatment and for a period afterwards as advised by their treating team. Men receiving this medicine should also use effective contraception. If you are planning a pregnancy, discuss it with your treating team before starting or stopping treatment.
🏥 Post-Surgery Considerations
This medicine can slow wound healing and increase the risk of infection and bleeding after surgery because it lowers blood counts. The timing of surgery and chemotherapy should be planned by your treating team. Inform your surgeon and oncologist about all medicines you are taking.
🦷 Dental Procedures
This medicine can lower blood counts and increase the risk of bleeding and infection after dental procedures. Tell your dentist that you are receiving this medicine before any dental work. Your treating team may advise blood tests before dental procedures and may recommend delaying non-urgent dental work until your counts recover.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Light activity such as short walks can help you feel better during treatment, but you should avoid strenuous exercise, heavy lifting, and contact sports, especially when your blood counts are low. Stop exercising and rest if you feel dizzy, short of breath, or very tired. Ask your treating team what level of activity is safe for you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause tiredness, nausea, and low blood counts, which may affect your ability to work and carry out daily activities. You should not drive or operate machinery immediately after the infusion or if you feel dizzy or unwell. Many patients need to take time off work during treatment cycles. Discuss your work schedule with your treating team so that treatment and rest can be planned safely.
🛑 When to Stop This Medicine
Do not stop or change your treatment on your own. This medicine is given under the supervision of a cancer specialist, who will decide when to stop based on your response, side effects, heart function, and blood counts. Contact your treating team immediately if you develop serious side effects such as chest pain, shortness of breath, fever, unusual bleeding, or severe allergic reactions.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of heart muscle damage, which may lead to heart failure. The risk depends on the total lifetime dose, previous heart disease, previous chest radiation, and other medicines used. Regular heart function tests are important during and after treatment. Long-term use can also increase the risk of secondary cancers such as leukaemia, and it can affect liver function. Patients should continue follow-up with their oncology team and report any new symptoms such as tiredness, shortness of breath, or swelling.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another form of the same active ingredient used for some of the same cancers. It may have a different side effect profile, especially heart effects.
Evidence: Well-establishedDepending on the cancer type, other chemotherapy medicines or targeted treatments may be options. These are decided by the treating oncologist.
Evidence: Well-established for selected cancersMedicines to control nausea, pain, and infection, along with nutrition and psychological support, are important alongside chemotherapy.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should be avoided during treatment with this medicine because the immune system is weakened and live vaccines can cause serious infection. Inactivated vaccines may be given, but the response may be reduced. Discuss all vaccines with your treating team before receiving them.
📦 Storage Guide
✅ DO
Store in a refrigerator at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Keep in the original carton to protect from light
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Check the expiry date before use
❌ DON'T
Do not use if the solution is discoloured or contains particles
✅ DO
Follow the storage instructions on the label
❌ DON'T
Do not store at room temperature for long periods unless the label says it is allowed
✈️ Traveling with This Medicine
This medicine is given in a hospital or clinic, so travel should be planned around treatment appointments. If you need to travel, carry a copy of your prescription and a letter from your treating oncologist explaining your diagnosis, treatment, and medicines. Keep the medicine in its original packaging and follow the storage instructions on the label. If you are flying, carry your medicines in hand luggage with proper documentation. Discuss any travel plans with your treating team well in advance so that monitoring tests and treatment cycles can be arranged safely.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine is given into a vein by a trained healthcare professional in a hospital or day-care chemotherapy setting. It is not for self-administration.
A: The schedule is decided by your treating oncologist. It is often given once every three to four weeks, but the exact schedule depends on your cancer type and how you tolerate treatment.
A: Watch for chest pain, shortness of breath, swelling of the legs, fever, chills, sore throat, unusual bruising or bleeding, and pain or swelling at the injection site. Report these to your treating team immediately.
A: This medicine can damage the heart muscle, so heart function is checked before and during treatment. The liposomal form is designed to reduce this risk compared with conventional doxorubicin, but it does not remove it completely.
A: This medicine can harm an unborn baby. Effective contraception is advised during treatment and for a period afterwards as advised by your treating team.
A: Breastfeeding should be stopped before treatment begins and should not be restarted until your treating team says it is safe.
🤔 Common Patient Concerns
🔄 Substitutes for adrisome 20mg injection
View AllAlternative brands with exact same active ingredient:
-
Natdox-LP InjectionNatco Pharma Ltd ₹3,282.65 31.3% CHEAPER
-
lipopeg 20mg injectionRPG Life Sciences Ltd ₹3,395.00 29% CHEAPER
-
pegadria 20mg injectionIntas Pharmaceuticals Ltd ₹3,829.50 19.9% CHEAPER
-
nudoxa 20mg injectionZydus Cadila ₹4,353.04 8.9% CHEAPER
-
lippod 20mg injectionCelon Laboratories Ltd ₹6,547.62 37% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a general cancer cure.
Fact: This medicine is used for specific cancers and is given as part of a treatment plan. It is not a cure for all cancers. - Myth: This medicine can be taken at home like a tablet.
Fact: This medicine must be given into a vein by a trained healthcare professional in a hospital or clinic. - Myth: The reddish-orange colour of urine means something is wrong.
Fact: This colour change is expected and harmless. It usually settles within a day or two after the infusion. - Myth: Hair loss from this medicine is permanent.
Fact: Hair loss is usually temporary, and hair often grows back after treatment ends. - Myth: This medicine has no effect on the heart.
Fact: This medicine can damage the heart muscle, so heart function is checked before and during treatment.
🔄 Alternative Options
Generic Alternatives
- Doxorubicin liposomal injection
Brand Alternatives
- Lippod 20mg injection