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ad coxib p 60mg/325mg tablet allopathy (Etoricoxib (60mg) + Paracetamol (325mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
ad coxib p 60mg/325mg tablet allopathy (Etoricoxib (60mg) + Paracetamol (325mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Adegen Pharma Private Limited. Contains Etoricoxib (60mg) + Paracetamol (325mg).

ad coxib p 60mg/325mg tablet - Uses, Price, Side Effects & Substitutes

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🏭 Adegen Pharma Private Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 22, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is ad coxib p 60mg/325mg tablet used for?

Auxib P 60mg/325mg Tablet (Etoricoxib + Paracetamol) is used to treat Acute pain. It contains Etoricoxib (60mg) + Paracetamol (325mg), which Etoricoxib selectively inhibits COX-2, reducing prostaglandin synthesis; paracet. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Etoricoxib + Paracetamol
  • Manufacturer: Adegen Pharma Private Limited
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 ad coxib p 60mg/325mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

ad coxib p 60mg/325mg tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Etoricoxib (60mg) + Paracetamol (325mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

📋 Drug Information

Generic Name(s)Etoricoxib + Paracetamol
Brand NameAuxib P 60mg/325mg Tablet
ManufacturerAdegen Pharma Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID (COX-2 inhibitor) + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; peak plasma concentration achieved in 1-2 hours for etoricoxib and 0.5-1 hour for paracetamol.
DistributionEtoricoxib: extensively distributed; paracetamol: uniformly distributed in body fluids.
Protein BindingEtoricoxib: ~92% bound to plasma proteins; paracetamol: 10-25% bound.
MetabolismEtoricoxib: hepatic via CYP3A4; paracetamol: hepatic via conjugation (glucuronidation, sulfation) and CYP2E1.
Half-LifeEtoricoxib: ~22 hours; paracetamol: ~2-3 hours.
ExcretionEtoricoxib: primarily renal (metabolites); paracetamol: renal (metabolites, <5% unchanged).
BioavailabilityEtoricoxib: ~100%; paracetamol: ~88%.
Onset of ActionEtoricoxib: 1-2 hours; paracetamol: 30-60 minutes.
Peak Plasma TimeEtoricoxib: 1-2 hours; paracetamol: 0.5-1 hour.
Duration of ActionEtoricoxib: ~24 hours; paracetamol: 4-6 hours.

Pharmacodynamics

Mechanism of ActionEtoricoxib selectively inhibits COX-2, reducing prostaglandin synthesis; paracetamol inhibits COX in the CNS and modulates descending serotonergic pathways.
Target ReceptorCOX-2 (etoricoxib); COX-1/COX-2 (paracetamol, central action).
Pharmacodynamic EffectsAnalgesic, anti-inflammatory, antipyretic.

💡 How and when to take ad coxib p 60mg/325mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture.

⚙️ How ad coxib p 60mg/325mg tablet Works

Etoricoxib selectively inhibits COX-2, reducing prostaglandin synthesis; paracetamol inhibits COX in the CNS and modulates descending serotonergic pathways.

1 Etoricoxib selectively inhibits COX-2 enzyme, reducing prostaglandin synthesis at sites of inflammation.
⬇️
2 Paracetamol inhibits COX-1 and COX-2 in the central nervous system, reducing prostaglandin synthesis and modulating pain pathways.
⬇️
3 Decreased prostaglandins lead to reduced pain, inflammation, and fever.

💊 ad coxib p 60mg/325mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Acute pain, osteoarthritis, rheumatoid arthritis, dental pain, dysmenorrhea, fever.

Off-label uses: Migraine, postoperative pain, cancer pain.

⚠️ What are the side effects of ad coxib p 60mg/325mg tablet?

✅ Common Side Effects

  • Nausea
  • Dyspepsia
  • Diarrhea
  • Headache
  • Dizziness
  • Edema

🚨 Serious Side Effects

  • GI bleeding
  • Cardiovascular events
  • Hepatotoxicity
  • Renal failure
  • Stevens-Johnson syndrome

⚠️ Rare Side Effects

  • Pancreatitis
  • Hepatitis
  • Aseptic meningitis
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Aspirin Major Increased GI ulceration risk
Methotrexate Major Increased methotrexate toxicity
Lithium Major Increased lithium levels
ACE inhibitors Major Reduced antihypertensive effect
Diuretics Major Reduced diuretic effect
Corticosteroids Moderate Increased GI ulceration risk
SSRIs Moderate Increased bleeding risk
Antiplatelet agents Moderate Increased bleeding risk
Alcohol Moderate Increased hepatotoxicity and GI bleeding
Antacids Minor Reduced absorption of etoricoxib
Cholestyramine Minor Reduced absorption of paracetamol

🚨 Major Interactions

  • Warfarin
  • Aspirin
  • Methotrexate
  • Lithium
  • ACE inhibitors
  • Diuretics

⚡ Moderate Interactions

  • Corticosteroids
  • SSRIs
  • Antiplatelet agents
  • Alcohol

ℹ️ Minor Interactions

  • Antacids
  • Cholestyramine

🍽️ Food Interactions

Avoid high-fat meals (may delay absorption), Grapefruit juice (may increase etoricoxib levels)

🍷 Alcohol Interaction

Increased risk of hepatotoxicity (paracetamol) and GI bleeding (etoricoxib).

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, active GI bleeding, severe hepatic impairment, severe renal impairment, pregnancy (third trimester), history of asthma with NSAIDs.

📊 Monitoring Parameters

Liver function, renal function, blood pressure, signs of GI bleeding.

🤱 Lactation Safety

Paracetamol is safe; etoricoxib is excreted in milk; use with caution.

💊 Overdose Management

Paracetamol: N-acetylcysteine; etoricoxib: symptomatic and supportive care.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose.

🛑 Myths vs. Facts about ad coxib p 60mg/325mg tablet

  • Myth: Generic substitutes of ad coxib p 60mg/325mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Etoricoxib (60mg) + Paracetamol (325mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of ad coxib p 60mg/325mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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