Servil D Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swallowing
- Swelling of face, lips, or throat
- Severe drowsiness or confusion
- Seizures or convulsions
- Fast or irregular heartbeat
- Hallucinations
- Severe allergic reaction with rash and itching
If experiencing severe symptoms, call emergency services immediately.
What is acutus tablet used for?
This medicine is a combination of chlorpheniramine maleate (an antihistamine) and dextromethorphan hydrobromide (a cough suppressant) used to treat dry cough and allergy symptoms such as runny nose and sneezing. It is available as a syrup for oral use.
- Generic Name: Chlorpheniramine Maleate (4mg) + Dextromethorphan Hydrobromide (15mg)
- Manufacturer: Acumen Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acutus tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोरफेनिरामाइन मेलिएट और डेक्सट्रोमेथोर्फन हाइड्रोब्रोमाइड का संयोजन है। इसका उपयोग सूखी खांसी और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना, गले में खुजली और आंखों में पानी आना के इलाज के लिए किया जाता है। यह खांसी को दबाने और एलर्जी को कम करने में मदद करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, जी मिचलाना और धुंधली दृष्टि शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, दौरे, और सांस लेने में कठिनाई हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। दवा लेने के बाद वाहन चलाने या मशीनरी चलाने से बचें। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 acutus tablet Uses & Benefits
[{"condition":"Cough due to cold or allergy","description":"This medicine suppresses dry, irritating cough and relieves associated allergy symptoms such as runny nose and sneezing.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Chlorpheniramine provides relief from sneezing, rhinorrhea, and itching of the nose or throat.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief of cough and nasal congestion associated with the common cold.","evidence":"Established"}]
Off-label uses: []
Primary treatment for: Cough and allergic rhinitis
Also treats: Common cold, Allergic cough, Upper respiratory tract infection
📋 Drug Information
| Generic Name(s) | Chlorpheniramine Maleate (4mg) + Dextromethorphan Hydrobromide (15mg) |
| Brand Name | acutus tablet |
| Manufacturer | Acumen Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors on effector cells, thereby reducing allergic symptoms such as sneezing, runny nose, and itching. It also has anticholinergic properties that contribute to dry mouth and drowsiness. Dextromethorphan hydrobromide is a centrally acting cough suppressant that acts on the cough center in the medulla oblongata. It is a non-opioid agent that raises the threshold for cough reflex by reducing the sensitivity of cough receptors in the brain. It does not have analgesic or addictive properties at therapeutic doses.
Mechanism Steps
💡 How to Take acutus tablet
Strength: Each 5 mL of syrup contains chlorpheniramine maleate 4 mg and dextromethorphan hydrobromide 15 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5-10 mL orally every 4-6 hours as needed, not to exceed 4 doses in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 2 years of age. For children 2-6 years, use only under medical supervision. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and confusion. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | For adults: maximum 40 mL in 24 hours (providing 32 mg chlorpheniramine and 120 mg dextromethorphan). Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acutus tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| CYP2D6 inhibitors | Major | |
| Alcohol | Major | |
| CNS depressants | Moderate | |
| Anticholinergics | Moderate | |
| SSRIs | Moderate | |
| Antihypertensives | Minor | |
| Levodopa | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- Alcohol
⚡ Moderate Interactions
- CNS depressants (e.g., benzodiazepines, opioids, sedatives)
- Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
- SSRIs (e.g., fluoxetine, sertraline)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and the risk of central nervous system depression. It may also impair your ability to drive or operate machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chlorpheniramine, dextromethorphan, or any component of the formulation","Use within 14 days of MAOI therapy","Children under 2 years of age","Severe liver disease","Respiratory depression","Acute asthma attack"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in patients with glaucoma, urinary retention, or prostatic hypertrophy.","Use with caution in elderly patients due to increased risk of confusion and falls.","Do not use for chronic cough or cough with excessive phlegm unless directed by a doctor.","Consult a doctor if symptoms persist beyond 7 days or are accompanied by fever, rash, or persistent headache."]
🤱 Lactation Safety
Chlorpheniramine and dextromethorphan are excreted in breast milk and may cause drowsiness in the infant. Consult your doctor before use during breastfeeding.
💊 Overdose Management
Overdose may cause severe drowsiness, dizziness, nausea, vomiting, hallucinations, seizures, respiratory depression, and coma. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not drink alcohol while taking this medicine because it can increase drowsiness and dizziness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine for a chronic cough or cough with excessive phlegm unless directed by a doctor. Keep out of reach of children. Store at room temperature away from direct sunlight and moisture. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and confusion. Use with caution and consider lower doses. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are planning to become pregnant. The safety of this medicine during pregnancy is not well established.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, as it may interact with other medications and increase the risk of side effects.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth and interact with other medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities requiring alertness until you know how this medicine affects you, as it may cause drowsiness and dizziness.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job requires alertness.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to tolerance, dependence, and increased risk of side effects such as drowsiness and cognitive impairment. Regular monitoring by a doctor is advised if long-term use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps relieve cough and nasal congestion.
Evidence: TraditionalSoothes throat and reduces cough.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor if you are due for any vaccinations while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30-60 minutes after oral administration.
A: Yes, you can take it with or without food. Taking with food may reduce stomach upset.
A: It is not recommended for children under 2 years. For children above 2 years, consult a pediatrician for appropriate dosing.
🤔 Common Patient Concerns
🔄 Substitutes for acutus tablet
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only provides symptomatic relief; it does not cure the underlying infection. - Myth: It is safe to take this medicine with alcohol.
Fact: Alcohol increases the risk of drowsiness and CNS depression; it should be avoided. - Myth: This medicine is safe for children under 2 years.
Fact: It is not recommended for children under 2 years due to risk of serious breathing problems.
🔄 Alternative Options
Generic Alternatives
- Chlorpheniramine + Dextromethorphan syrup (generic)