actisprin 75mg tablet - Aspirin (75mg) medicine

actisprin 75mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Alkem Laboratories Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is actisprin 75mg tablet used for?

Aspirin 300mg Tablet (Aspirin) is used to treat BLOOD RELATED. It contains Aspirin (75mg), which Irreversibly acetylates cyclooxygenase (COX-1 and COX-2), inhibiting prostagland. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Aspirin
  • Manufacturer: Alkem Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š actisprin 75mg tablet Uses & Benefits

Mild to moderate pain, fever, inflammation, prevention of cardiovascular events (low dose).

Off-label uses: Prevention of preeclampsia, prevention of colorectal cancer.

๐Ÿ“‹ Drug Information

Generic Name(s)Aspirin
Brand NameAspirin 300mg Tablet
ManufacturerAlkem Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (Salicylates)
Route of AdministrationOral.
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed from the gastrointestinal tract.
DistributionWidely distributed throughout body tissues and fluids; crosses placenta and enters breast milk.
Protein Binding80-90% bound to plasma proteins, primarily albumin.
MetabolismHepatic metabolism via hydrolysis to salicylic acid, then conjugated with glycine and glucuronic acid.
Half-Life15-20 minutes (aspirin); 2-3 hours (salicylic acid at low doses, up to 15-30 hours at high doses).
ExcretionRenal excretion of salicylates and metabolites; pH-dependent.
Bioavailability50-75% (oral); undergoes first-pass metabolism.
Onset of Action5-30 minutes (analgesic/antipyretic); 1-2 hours (antiplatelet).
Peak Plasma Time1-2 hours (salicylic acid).
Duration of Action4-6 hours (analgesic/antipyretic); 7-10 days (antiplatelet effect).

How It Works

Irreversibly acetylates cyclooxygenase (COX-1 and COX-2), inhibiting prostaglandin and thromboxane synthesis.

Mechanism Steps

1Aspirin irreversibly acetylates serine residue in COX-1 and COX-2 active site.
2Inhibition of COX-1 reduces thromboxane A2 synthesis in platelets, inhibiting platelet aggregation.
3Inhibition of COX-2 reduces prostaglandin synthesis, leading to analgesic, antipyretic, and anti-inflammatory effects.

๐Ÿ’ก How to Take actisprin 75mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of actisprin 75mg tablet

โœ… Common Side Effects

  • Nausea
  • Dyspepsia
  • Gastric irritation
  • Heartburn
  • Increased bleeding time

๐Ÿšจ Serious Side Effects

  • Gastrointestinal bleeding
  • Peptic ulcer
  • Reye's syndrome
  • Anaphylaxis
  • Hemolytic anemia

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Nephrotoxicity
  • Tinnitus
  • Salicylate poisoning
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Heparin Major Increased bleeding risk
Clopidogrel Major Increased bleeding risk
Ibuprofen Major Reduced antiplatelet effect of aspirin
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect
Corticosteroids Moderate Increased GI bleeding risk
SSRIs Moderate Increased bleeding risk
Valproic acid Moderate Increased valproate toxicity
Antacids Minor Reduced aspirin absorption
Caffeine Minor Enhanced analgesic effect
Zinc Minor Reduced zinc absorption

๐Ÿšจ Major Interactions

  • Warfarin
  • Methotrexate
  • Heparin
  • Clopidogrel
  • Ibuprofen

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Corticosteroids
  • SSRIs
  • Valproic acid

โ„น๏ธ Minor Interactions

  • Antacids
  • Caffeine
  • Zinc

๐Ÿฝ๏ธ Food Interactions

Food delays absorption but not extent; avoid high-fat meals.

๐Ÿท Alcohol Interaction

Increased risk of gastrointestinal bleeding.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to NSAIDs, active peptic ulcer, bleeding disorders, severe hepatic/renal impairment, children with viral infections (Reye's syndrome), third trimester pregnancy.

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, bleeding time, serum salicylate levels (in toxicity).

๐Ÿคฑ Lactation Safety

Caution; excreted in breast milk; avoid high doses.

๐Ÿ’Š Overdose Management

Activated charcoal, gastric lavage, supportive care; severe cases may require hemodialysis.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for actisprin 75mg tablet

View All

Alternative brands with exact same active ingredient (Aspirin (75mg)):

Medical Note: Always consult your doctor before switching medications.

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