acstop soap - Clindamycin (1%) + Nicotinamide (0.5%) medicine

Acstop Soap: Complete Guide to Uses, Side Effects, and Safety

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🏭 Sol Derma Pharmaceuiticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 18, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for topical clindamycin in acne; limited for the combination with nicotinamide in a soap base.
Reviewed by
SaathiMed Expert Panel | Oct 18, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction with swelling of face, lips, or throat
  • Difficulty breathing or swallowing
  • Severe or persistent diarrhea
  • Blood in stool or severe abdominal pain
  • Extreme skin redness, blistering, or peeling
  • Signs of infection such as pus or fever

If experiencing severe symptoms, call emergency services immediately.

What is acstop soap used for?

This medicine is a topical cleansing bar containing clindamycin 1% and nicotinamide 0.5%. It is used to treat mild to moderate acne by reducing acne-causing bacteria and inflammation. Use it once or twice daily as directed by your doctor.

  • Generic Name: Clindamycin + Nicotinamide
  • Manufacturer: Sol Derma Pharmaceuiticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 acstop soap के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल साबुन है जिसमें क्लिंडामाइसिन 1% और निकोटिनामाइड 0.5% होता है। इसका उपयोग हल्के से मध्यम मुँहासे (एक्ने) के इलाज के लिए किया जाता है। यह मुँहासे पैदा करने वाले बैक्टीरिया को कम करने और सूजन को शांत करने में मदद करता है। इसे डॉक्टर के निर्देशानुसार दिन में एक या दो बार चेहरे को धोने के लिए उपयोग करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में त्वचा का सूखना, पपड़ी बनना, खुजली या जलन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर एलर्जी प्रतिक्रिया दुर्लभ है, लेकिन अगर सूजन, चकत्ते या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का उपयोग केवल त्वचा पर करें। आँखों, होंठों और श्लेष्मा झिल्ली के संपर्क से बचें। टूटी या जली हुई त्वचा पर न लगाएं। उपयोग से पहले और बाद में हाथ धोएं। अगर सूखापन हो तो मॉइस्चराइज़र का उपयोग करें। धूप से बचें और सनस्क्रीन लगाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 acstop soap Uses & Benefits

[{"condition":"Acne vulgaris","description":"Used as a topical cleansing bar to reduce acne-causing bacteria and inflammation in mild to moderate acne.","evidence":"Well-established"},{"condition":"Acne with post-inflammatory hyperpigmentation","description":"Nicotinamide may help reduce pigmentation and improve skin tone in acne-prone individuals.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Rosacea","description":"Sometimes used off-label for its anti-inflammatory and antibacterial effects, but evidence is limited.","evidence":"Limited"},{"condition":"Folliculitis","description":"May be used off-label for bacterial folliculitis, but not a standard first-line treatment.","evidence":"Limited"}]

Primary treatment for: Acne vulgaris

Also treats: Acne with post-inflammatory hyperpigmentation, Folliculitis

📋 Drug Information

Generic Name(s)Clindamycin + Nicotinamide
Brand NameAcnetoin Gel
ManufacturerSol Derma Pharmaceuiticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntibiotic + Vitamin B3 derivative
Route of AdministrationTopical
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the soap in its original packaging.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Use lukewarm water to wash your face, as hot water can worsen irritation.
2
Apply a non-comedogenic moisturizer after washing to prevent dryness.
3
Avoid using other abrasive or alcohol-based products on the same area.
4
Use sunscreen daily, as some acne treatments can increase sun sensitivity.
5
Do not stop using the soap abruptly without consulting your doctor, even if acne improves.
6
If you wear makeup, choose oil-free and non-comedogenic products.
7
Keep the soap dry between uses to prevent bacterial contamination.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Mild to moderate acne
This medicine is commonly prescribed for this.
Likely Use
❌
Severe cystic acne
This medicine may not be sufficient; consult a dermatologist.
Not Primary
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionClindamycin is minimally absorbed through intact skin after topical application. Systemic absorption is generally low but may increase if applied to large areas or broken skin. Nicotinamide is absorbed through the skin and can penetrate the stratum corneum.
DistributionNot established from the available information for topical use.
Protein BindingNot established from the available information for topical use.
MetabolismNot established from the available information for topical use.
Half-LifeNot established from the available information for topical use.
ExcretionNot established from the available information for topical use.
BioavailabilityNot established from the available information for topical use.
Onset of ActionImprovement in acne may be noticed within 2 to 4 weeks of regular use, but full benefits may take 8 to 12 weeks.
Peak Plasma TimeNot established from the available information for topical use.
Duration of ActionNot established from the available information for topical use.

How It Works

Clindamycin binds to the 50S ribosomal subunit of susceptible bacteria and inhibits protein synthesis, thereby stopping bacterial growth. Nicotinamide, also known as niacinamide, is a form of vitamin B3 that supports cellular metabolism, reduces inflammation, and helps regulate sebum production. Together, they help reduce acne lesions and improve skin condition.

Mechanism Steps

1
Clindamycin uptake by bacteria: Clindamycin penetrates the bacterial cell wall and reaches the ribosome.
2
Inhibition of protein synthesis: Clindamycin binds to the 50S ribosomal subunit, blocking peptide bond formation and preventing bacterial protein synthesis.
3
Nicotinamide anti-inflammatory action: Nicotinamide inhibits inflammatory cytokines and reduces oxidative stress in skin cells.
4
Sebum regulation: Nicotinamide helps normalize sebum production, reducing pore blockage.

💡 How to Take acstop soap

Strength: Cleansing bar containing clindamycin 1% and nicotinamide 0.5%.

1Wet your face or affected area with lukewarm water.
2Rub the soap between your hands to create a lather.
3Gently massage the lather onto the affected area.
4Avoid contact with eyes, lips, and mucous membranes.
5Rinse thoroughly with water and pat dry.
6Wash your hands after use.
7Follow with a non-comedogenic moisturizer if needed.

Dosage Information

Adult DosageUse this medicine as a cleansing bar to wash the affected area once or twice daily, or as directed by your doctor. Wet the skin, gently massage the soap onto the affected area, and rinse thoroughly with water. Pat dry. Dose and frequency must be individualized by a qualified clinician based on the severity of acne and skin sensitivity.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician or dermatologist for use in children.
Elderly DosageNo specific dosage adjustments are required for elderly patients. Use as directed by a doctor.
Renal ImpairmentNo dosage adjustment is required for topical use in patients with renal impairment.
Hepatic ImpairmentNo dosage adjustment is required for topical use in patients with hepatic impairment.
Maximum Daily DoseNot established from the available information. Use as directed by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of acstop soap

✅ Common Side Effects

Skin dryness (Common (5-10%))
Use a gentle moisturizer and reduce frequency if severe.
Peeling (Common (5-10%))
Avoid harsh scrubs and moisturize regularly.
Itching (Common (5-10%))
Discontinue if persistent and consult a doctor.
Burning sensation (Common (5-10%))
Rinse with cool water and apply a soothing moisturizer.

🚨 Serious Side Effects

Severe allergic reaction (Rare (<0.1%))
Seek immediate medical attention if you experience swelling, rash, or difficulty breathing.
Antibiotic-associated colitis (Very rare (<0.01%))
Report severe or persistent diarrhea to a doctor immediately.

⚠️ Rare Side Effects

Contact dermatitis
Stop use and consult a dermatologist.
Skin discoloration
Consult a doctor if concerned.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Erythromycin (topical) Major
Tretinoin (topical) Moderate
Benzoyl peroxide Moderate

🚨 Major Interactions

  • Other topical antibiotics (e.g., erythromycin)

⚡ Moderate Interactions

  • Topical retinoids
  • Abrasive soaps and cleansers

🍷 Alcohol Interaction

No known interaction with alcohol when used topically. However, alcohol consumption may worsen acne and should be limited.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to clindamycin, nicotinamide, or any component of the formulation","History of regional enteritis, ulcerative colitis, or antibiotic-associated colitis","Use on broken or eczematous skin"]

⚠️ Warnings & Precautions

["For external use only. Avoid contact with eyes, lips, and mucous membranes.","Do not use on large areas of broken skin without medical advice.","Prolonged use may lead to bacterial resistance.","If severe diarrhea develops, discontinue use and consult a doctor.","Keep out of reach of children.","Consult a doctor if condition worsens or does not improve after 8-12 weeks."]

🤱 Lactation Safety

It is not known whether clindamycin or nicotinamide is excreted in breast milk after topical use. Consult your doctor before using this product while breastfeeding. Avoid applying to the breast area to prevent infant exposure.

💊 Overdose Management

Overdose with topical clindamycin and nicotinamide is unlikely due to low systemic absorption. If accidental ingestion occurs, seek medical attention immediately. Symptoms may include nausea, vomiting, or diarrhea. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Use this medicine only on the skin as directed by your doctor. Avoid contact with eyes, lips, and mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to broken or irritated skin. Wash your hands before and after applying the product. Use a gentle, non-comedogenic moisturizer if dryness occurs. Avoid using other topical acne products unless advised by your doctor, as they may increase irritation. Protect your skin from excessive sunlight and use a broad-spectrum sunscreen. Do not share this medicine with others. Keep out of reach of children. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this product. Do not use this medicine for any condition other than the one for which it was prescribed.

👴 Special Considerations for Elderly

💡 For Patients Above 65

No specific precautions for elderly patients using this medicine topically. However, skin may be more sensitive, so use with caution and moisturize regularly.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are pregnant, planning pregnancy, or breastfeeding. Topical clindamycin is generally considered low risk, but medical advice is essential.

🏥 Post-Surgery Considerations

Avoid applying this medicine to surgical wounds or broken skin unless advised by your doctor. Consult your surgeon before resuming use after surgery.

🦷 Dental Procedures

No specific considerations for dental procedures. Inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Wash your face gently twice daily with a mild cleanser.
🥗
Avoid picking or squeezing pimples to prevent scarring.
😴
Maintain a balanced diet low in refined sugars and dairy if they trigger your acne.
💧
Manage stress through yoga, meditation, or regular exercise.
🧘
Get 7-8 hours of sleep to support skin health.
🌞
Keep your phone screen and pillowcases clean.

🏋️ Exercise Considerations

Exercise is generally safe while using this medicine. However, sweat may irritate the skin, so wash your face with cool water after workouts. Avoid sharing towels or gym equipment that may come into contact with your face.

🥗 Diet Recommendations

Include plenty of fruits and vegetables rich in antioxidants.
Reduce intake of high-glycemic foods like sugary snacks and white bread.
Stay well hydrated by drinking adequate water.
Consider limiting dairy if you notice it worsens your acne.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. It is applied topically and has minimal systemic effects. You can continue your normal daily activities, but avoid touching your face unnecessarily.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if you experience severe irritation, allergic reaction, or if your acne does not improve after 8-12 weeks. Do not stop abruptly if you are seeing improvement without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of topical clindamycin may lead to bacterial resistance. It is advisable to use it for the duration prescribed by your doctor and not indefinitely. Regular follow-up with a dermatologist is recommended to assess ongoing need and to monitor for any skin changes.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Salicylic acid cleansers

Can help unclog pores and reduce mild acne.

Evidence: Well-established
Benzoyl peroxide

Effective for mild to moderate acne but can be drying.

Evidence: Well-established
Tea tree oil

May have antibacterial properties but evidence is limited.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling to a different time zone, continue your regular application schedule. Keep it in your carry-on luggage if possible. Check customs regulations for topical antibiotics before international travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 22-year-old college student with mild acne
She started using this medicine twice daily as prescribed. After 4 weeks, she noticed fewer pimples and less oiliness. She experienced mild dryness initially, which improved with a moisturizer.
💡 Lesson: Consistent use and proper moisturizing can help manage side effects and improve results.
👤 A 30-year-old professional with acne and dark spots
He used this medicine once daily for 8 weeks. His acne reduced, and the dark spots gradually faded. He was advised to use sunscreen daily to prevent further pigmentation.
💡 Lesson: Combining this medicine with sun protection can enhance overall skin improvement.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start seeing improvement in 2 to 4 weeks, but full benefits may take 8 to 12 weeks of regular use.

Q: Can I use this soap on my body?

A: It is primarily intended for facial acne. Consult your doctor before using it on other areas.

Q: Does it bleach clothes?

A: No, this medicine does not contain bleaching agents like benzoyl peroxide.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this soap long-term?
  • Will it make my skin dry?
  • Can I use it with other acne creams?
  • Is it safe for sensitive skin?
  • What if I miss a dose?
  • Can I use it during pregnancy?

🛑 Myths vs. Facts

  • Myth: This soap can cure acne permanently.
    Fact: Acne is a chronic condition that can be managed but not permanently cured with a single product.
  • Myth: Using more of this soap will clear acne faster.
    Fact: Using more than directed can cause irritation and dryness without improving results.
  • Myth: Antibiotic soaps are safe for daily long-term use without resistance.
    Fact: Prolonged use of topical antibiotics can lead to bacterial resistance; use as prescribed.

🔄 Alternative Options

Generic Alternatives

  • Clindamycin 1% topical solution
  • Nicotinamide 0.5% topical cream

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredient":"Clindamycin 1% + Nicotinamide 0.5%","form":"Soap","primary_use":"Acne vulgaris"},{"medicine":"Clindamycin 1% gel","active_ingredient":"Clindamycin 1%","form":"Gel","primary_use":"Acne vulgaris"},{"medicine":"Nicotinamide 4% gel","active_ingredient":"Nicotinamide 4%","form":"Gel","primary_use":"Acne and hyperpigmentation"}]

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