actame 20mg tablet allopathy (Isotretinoin (20mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
actame 20mg tablet allopathy (Isotretinoin (20mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Sol Derma Pharmaceuiticals Pvt Ltd. Contains Isotretinoin (20mg).

actame 20mg tablet - Uses, Price, Side Effects & Substitutes

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Isotretinoin (20mg) (Click to see all medicines with same salt)
🏭 Sol Derma Pharmaceuiticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 22, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is actame 20mg tablet used for?

Acutret 10 Capsule (Isotretinoin) is used to treat Severe recalcitrant nodular acne. It contains Isotretinoin (20mg), which Reduces sebum production, normalizes follicular keratinization, inhibits Propion. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Isotretinoin
  • Manufacturer: Sol Derma Pharmaceuiticals Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 actame 20mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

actame 20mg tablet का उपयोग मुख्य रूप से derma और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Isotretinoin (20mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

📋 Drug Information

Generic Name(s)Isotretinoin
Brand NameAcutret 10 Capsule
ManufacturerSol Derma Pharmaceuiticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassRetinoids- First generation
Route of AdministrationOral.
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed orally with high bioavailability; absorption enhanced with food.
DistributionExtensively distributed; crosses placenta; enters breast milk.
Protein Binding99.9% bound to albumin.
MetabolismHepatic metabolism via CYP450 enzymes to active metabolites (4-oxo-isotretinoin).
Half-Life20-24 hours for parent drug; longer for metabolites.
ExcretionExcreted in urine and feces equally.
Bioavailability25% (increased with food).
Onset of Action1-2 weeks for initial improvement.
Peak Plasma Time3-4 hours.
Duration of ActionTherapeutic effect persists weeks after discontinuation.

Pharmacodynamics

Mechanism of ActionReduces sebum production, normalizes follicular keratinization, inhibits Propionibacterium acnes growth, and has anti-inflammatory effects.
Target ReceptorRetinoic acid receptors (RARs) and retinoid X receptors (RXRs).
Pharmacodynamic EffectsDecreased sebum excretion, reduced comedogenesis, anti-inflammatory, and antimicrobial.

💡 How and when to take actame 20mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from light and moisture.

⚙️ How actame 20mg tablet Works

Reduces sebum production, normalizes follicular keratinization, inhibits Propionibacterium acnes growth, and has anti-inflammatory effects.

1 Binds to retinoic acid receptors (RARs) and retinoid X receptors (RXRs) in the nucleus.
⬇️
2 Modulates gene transcription involved in cell growth, differentiation, and apoptosis.
⬇️
3 Reduces sebocyte proliferation and sebum production.
⬇️
4 Normalizes follicular keratinization, preventing comedone formation.
⬇️
5 Inhibits Propionibacterium acnes growth indirectly by altering sebum composition.
⬇️
6 Exerts anti-inflammatory effects by inhibiting neutrophil chemotaxis and cytokine production.

💊 actame 20mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Severe recalcitrant nodular acne, acne vulgaris unresponsive to other therapies.

Off-label uses: Rosacea, hidradenitis suppurativa, psoriasis, skin cancer prevention.

⚠️ What are the side effects of actame 20mg tablet?

✅ Common Side Effects

  • Cheilitis
  • Dry skin
  • Xerophthalmia
  • Epistaxis
  • Arthralgia
  • Myalgia
  • Headache
  • Increased triglycerides

🚨 Serious Side Effects

  • Pseudotumor cerebri
  • Hepatotoxicity
  • Pancreatitis
  • Depression/suicidal ideation
  • Inflammatory bowel disease
  • Teratogenicity

⚠️ Rare Side Effects

  • Thrombocytopenia
  • Agranulocytosis
  • Vasculitis
  • Hearing impairment
  • Osteoporosis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Tetracyclines Major Increased risk of pseudotumor cerebri
Vitamin A supplements Major Additive toxicity (hypervitaminosis A)
Methotrexate Major Increased hepatotoxicity risk
Oral contraceptives Major Reduced contraceptive efficacy
Phenytoin Moderate Increased phenytoin levels
Corticosteroids Moderate Increased osteoporosis risk
Azole antifungals Moderate Increased retinoid toxicity
Alcohol Minor Increased hepatotoxicity risk
Antacids Minor Reduced isotretinoin absorption

🚨 Major Interactions

  • Tetracyclines
  • Vitamin A supplements
  • Methotrexate
  • Oral contraceptives (reduced efficacy)

⚡ Moderate Interactions

  • Phenytoin
  • Corticosteroids
  • Antifungals (azole)

ℹ️ Minor Interactions

  • Alcohol
  • Antacids

🍽️ Food Interactions

High-fat meals increase absorption.

🍷 Alcohol Interaction

May increase risk of hepatotoxicity; avoid concurrent use.

🛡️ Safety & Warnings

🚫 Contraindications

Pregnancy, breastfeeding, hypersensitivity to retinoids, hypervitaminosis A, severe hepatic impairment.

📊 Monitoring Parameters

Liver function tests, serum lipids, pregnancy test (monthly), CBC, renal function.

🤱 Lactation Safety

Contraindicated; excreted in breast milk.

💊 Overdose Management

Supportive care; symptoms include headache, vomiting, facial flushing, cheilitis, abdominal pain. No specific antidote.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

🛑 Myths vs. Facts about actame 20mg tablet

  • Myth: Generic substitutes of actame 20mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Isotretinoin (20mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of actame 20mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

Relative ne face dekha toh ghar ke nuskhe pe lecture de diya 😭 Cystic acne scars ka koi asli solution do yaar!

Yaar itni frustration ho rahi hai 😭. Kal mera ek relative aaya and straight up bola, “Beta face pe ye kya ho gaya? Chandan lagao, besan lagao.” Jaise maine kuch try nahi kiya! I know they mean well but itna irritating hota hai jab woh samajhte hain ki ghar ke nuskhe se sab theek ho jayega. Cystic acne hai bhai, ye normal pimple nahi hai. Aur maine jo pimple popping ki aadat daali hai na, uske daag ab permanently hi dikhte hain lagta hai. Koi genuine tips do please. I’m currently using niacinamide serum and aloe vera gel, but scars ka koi fark nahi pad raha. Koi specific cream ya dermatologist ka koi remedy batado jo kaam kare? Sunscreen bhi lagati hoon lekin glow nahi aa raha. Filter ke bina selfie lene ka mann nahi karta ab. 😔 Aur haan, please “haldi aur doodh” mat bolna, woh try kar chuki hoon. Kuch actual skincare routine chahiye jo cystic acne scars ke liye effective ho. Pls help! 🙏

Bald ho jaaogi ya weight wapas? IF chhodun ya jaan jokhim mein daalun? 😭

Yaar mujhe samajh nahi aa raha kya karun. 6 months pehle maine intermittent fasting start kiya tha (16:8, kuch din 18:6 bhi kar leti thi). Weight loss toh hua tha shuru mein, lekin ab 2 months se hair fall bohot zyada ho raha hai. Har roz nahate waqt haath mein guchhe aate hain. Mera dermatologist bola ki yeh protein aur iron deficiency hai, fasting ki wajah se. Maine socha tha IF toh easy hai, khaana toh kha leti hoon. But honestly, main proper nutritious khana nahi kha pati thi - bas 8 ghante mein jo bhi milta hai kha leti thi. Ab main omega 3 supplements le rahi hoon, flax seeds, makhana, eggs, palak sab kuch daal rahi hoon khane mein. But hair fall ruk nahi raha. Kisi ko koi remedy aata hai? Ya kya karna chahiye? Main soch rahi hoon ab IF chhod doon, lekin weight wapas aa jayega toh aur depression ho jayega. Already metabolism kharab hai crash diets se. Please help karo! 😭

Intermittent fasting se baal jhad rahe? 30 ki umar mein 50 jaisi ho gayi!

Aaj subah jab brush kiya toh haath mein baal ka guchha dekh ke ruk gaya. Seriously, I'm only 30 but lagta hai 50 ki ho gayi hoon. 6 months pehle maine intermittent fasting start kiya tha - 16:8, fir 18:6 bhi try kiya. Weight toh kuch nahi hua but hair fall bohot zyada ho gaya. Pehle toh maine socha stress hai, but phir pata chala ki fasting se nutrition deficiency ho sakti hai. Mummy roz bolti hain, "Beta itna diet karke kya karogi? Baal toh jhad rahe hain." Aur sahi keh rahi hain. Ab maine koi bhi diet nahi kiya, but weight bhi nahi gaya. Metabolism kharab ho chuka hai. Kal hi dermatologist ke paas gaya - vitamins check karwaye. Iron aur Vitamin D kam hai. Koi batao, kya intermittent fasting se hair fall hua hai kisi ko? Aur agar main ab normal khaana shuru kar doon toh kya yeh rukega? Ya fir koi specific supplements loon? Fed up ho gayi hoon apne aap se. Help karo yaar.

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