Acrovin 100mg Injection (Tirofiban): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe or uncontrollable bleeding from any site
- Black, tarry stools or vomiting blood
- Sudden severe headache, confusion, or vision changes
- Difficulty breathing or chest pain
- Swelling of face, lips, tongue, or throat
- Decreased urine output or swelling in legs
- Unusual bruising or petechiae
If experiencing severe symptoms, call emergency services immediately.
What is acrovin 100mg injection used for?
This medicine is a glycoprotein IIb/IIIa inhibitor used in hospitals to prevent blood clots in patients with acute coronary syndrome or those undergoing angioplasty. It is given intravenously and requires close monitoring for bleeding.
- Generic Name: Tirofiban (100mg)
- Manufacturer: Vintech Formulations
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acrovin 100mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा टिरोफिबान नामक सक्रिय तत्व से बनी एक इंजेक्शन है, जिसका उपयोग अस्पताल में हृदय रोगियों में रक्त के थक्के बनने से रोकने के लिए किया जाता है। यह उन मरीजों के लिए दी जाती है जिन्हें तीव्र कोरोनरी सिंड्रोम है या जिनकी एंजियोप्लास्टी हो रही है। यह दवा खून को पतला करने का काम करती है और दिल के दौरे के खतरे को कम करती है। यह केवल डॉक्टर की देखरेख में अस्पताल में ही दी जाती है।
साइड इफेक्ट्स: इस दवा के सबसे आम दुष्प्रभावों में रक्तस्राव, जी मिचलाना, सिरदर्द और बुखार शामिल हैं। गंभीर दुष्प्रभावों में अत्यधिक रक्तस्राव और प्लेटलेट्स की संख्या में कमी हो सकती है। यदि आपको असामान्य रक्तस्राव, चोट लगने पर खून बहना, या काला मल दिखे तो तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल अस्पताल में डॉक्टर या नर्स द्वारा ही दी जानी चाहिए। इसे घर पर स्वयं न लें। इस दवा को लेते समय अपने डॉक्टर को अपनी सभी दवाओं और बीमारियों के बारे में बताएं। इलाज के दौरान खून की जांच नियमित रूप से करवाएं। गर्भवती या स्तनपान कराने वाली महिलाएं इस दवा का उपयोग करने से पहले डॉक्टर से सलाह लें।
💊 acrovin 100mg injection Uses & Benefits
[{"condition":"Acute Coronary Syndrome (ACS)","description":"Used to reduce the risk of thrombotic cardiovascular events in patients with unstable angina or non-ST-elevation myocardial infarction, especially when percutaneous coronary intervention is planned.","evidence":"Well-established"},{"condition":"Percutaneous Coronary Intervention (PCI)","description":"Administered during PCI to prevent platelet aggregation and reduce the risk of abrupt closure of the coronary artery.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Adjunctive therapy in carotid artery stenting","description":"Sometimes used off-label to prevent thromboembolic complications during carotid artery stenting procedures.","evidence":"Limited"}]
Primary treatment for: Acute Coronary Syndrome
Also treats: Unstable angina, Non-ST-elevation myocardial infarction, Percutaneous coronary intervention
📋 Drug Information
| Generic Name(s) | Tirofiban (100mg) |
| Brand Name | acrovin 100mg injection |
| Manufacturer | Vintech Formulations |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Glycoprotein IIb/IIIa inhibitors |
| Route of Administration | Parenteral (intravenous) |
| Storage | Store at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a non-peptide tyrosine derivative that acts as a reversible antagonist of the glycoprotein IIb/IIIa receptor on the surface of platelets. By binding to this receptor, it prevents fibrinogen and von Willebrand factor from cross-linking platelets, thereby inhibiting the final common pathway of platelet aggregation. This action is dose-dependent and reversible upon discontinuation of the infusion.
Mechanism Steps
💡 How to Take acrovin 100mg injection
Strength: Injection: 100 mg per vial (as a concentrate for solution for infusion).
Dosage Information
| Adult Dosage | The dosage of this medicine is individualized by a qualified clinician based on the patient's condition, weight, and renal function. For acute coronary syndrome, a common regimen is an intravenous loading dose of 0.4 mcg/kg/min for 30 minutes followed by a maintenance infusion of 0.1 mcg/kg/min. For percutaneous coronary intervention, a loading dose of 10 mcg/kg over 3 minutes followed by 0.15 mcg/kg/min for up to 18 hours is often used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function and are at increased risk of bleeding. Dose should be carefully adjusted based on renal function. No specific dose adjustment is recommended solely based on age, but close monitoring is advised. |
| Renal Impairment | In patients with severe renal impairment (creatinine clearance <30 mL/min), the dose of this medicine should be reduced by 50%. For example, the maintenance infusion rate should be halved. Close monitoring is required. |
| Hepatic Impairment | No dose adjustment is required for hepatic impairment as the drug is primarily excreted unchanged by the kidneys. |
| Maximum Daily Dose | The maximum daily dose is not fixed and depends on the clinical scenario. It is administered as a continuous infusion and the total daily dose is determined by the infusion rate and duration, which are individualized by the clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acrovin 100mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Heparin | Major | |
| Aspirin | Major | |
| Clopidogrel | Major | |
| Alteplase | Major | |
| Ibuprofen | Moderate | |
| Naproxen | Moderate | |
| Fluoxetine | Moderate | |
| Corticosteroids | Minor |
🚨 Major Interactions
- Anticoagulants (e.g., warfarin, heparin)
- Other antiplatelet agents (e.g., aspirin, clopidogrel)
- Thrombolytic agents (e.g., alteplase)
⚡ Moderate Interactions
- NSAIDs (e.g., ibuprofen, naproxen)
- SSRIs (e.g., fluoxetine)
🍷 Alcohol Interaction
Alcohol may increase the risk of gastrointestinal bleeding and should be avoided while receiving this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active internal bleeding","History of bleeding diathesis or thrombocytopenia","Recent major surgery or trauma","Severe uncontrolled hypertension","Acute pericarditis","Known hypersensitivity to tirofiban"]
⚠️ Warnings & Precautions
["This medicine should be used with caution in patients with a history of bleeding disorders.","Dose reduction is required in patients with severe renal impairment.","Thrombocytopenia can occur; monitor platelet counts regularly.","Avoid concomitant use with other drugs that increase bleeding risk.","Elderly patients may be at higher risk of bleeding."]
🤱 Lactation Safety
It is not known whether this medicine is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose of this medicine may result in severe bleeding. There is no specific antidote. Treatment should be symptomatic and supportive. Platelet transfusion may be considered in cases of severe thrombocytopenia or bleeding. Discontinue the infusion immediately.
⏰ Missed Dose
This medicine is administered as a continuous intravenous infusion in a hospital setting. Missed doses are not applicable as it is given under medical supervision.
Additional Safety Advice
This medicine must only be administered by a qualified healthcare professional in a hospital setting. It is not for home use. Patients should inform their doctor about all medications they are taking, especially blood thinners, and any history of bleeding disorders, recent surgery, or kidney disease. Regular monitoring of platelet count, hemoglobin, and signs of bleeding is essential during treatment. Do not breastfeed while receiving this medicine. Avoid activities that may cause injury or bleeding. Report any unusual bleeding, bruising, or dark urine immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of bleeding and may have reduced renal function. Dose adjustment based on renal function is necessary. Close monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss with your doctor before receiving this medicine. It should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
This medicine increases the risk of bleeding after surgery. It should be used with caution in the postoperative period. Inform your surgeon if you have recently received this medicine.
🦷 Dental Procedures
Inform your dentist if you have recently received this medicine, as it may increase the risk of bleeding during dental procedures. Your dentist may recommend postponing elective procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may cause injury or bleeding while receiving this medicine. Consult your doctor before resuming exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital setting, so it will not affect your work directly. However, you may need to take time off for the procedure and recovery. Discuss with your employer about leave requirements.
🛑 When to Stop This Medicine
This medicine is stopped by your healthcare provider based on your clinical condition. Do not attempt to stop or adjust the infusion yourself. If you experience severe bleeding or other serious side effects, inform your doctor immediately.
📅 Long-Term Use Effects
Long-term effects of this medicine are not well studied as it is typically used for short durations in acute settings. Prolonged use may increase the risk of bleeding and thrombocytopenia. Regular monitoring of platelet count and bleeding signs is essential during therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May be used alone or in combination depending on the clinical scenario.
Evidence: Well-establishedUsed to prevent clot formation but with a different mechanism.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store in refrigerator at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Keep in original carton to protect from light
❌ DON'T
Do not use if solution is discolored or contains particles
✅ DO
Follow hospital storage protocols
❌ DON'T
Do not store at room temperature for extended periods
✈️ Traveling with This Medicine
This medicine is administered only in a hospital setting, so travel advice is not applicable. If you are discharged on other medications, carry them in original packaging with a prescription copy. For air travel, keep medications in carry-on luggage. Consult your doctor before traveling if you have recently received this medicine.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within minutes after the intravenous infusion begins.
A: No, you should not drive or operate machinery immediately after receiving this medicine as you will be monitored in the hospital.
A: This medicine is given as a continuous infusion in the hospital, so missed doses are not applicable.
A: There is limited data on its use in pregnancy. It should be used only if clearly needed, as determined by your doctor.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: Acrovin 100mg injection can be taken at home.
Fact: This medicine is given only in a hospital setting under medical supervision. - Myth: Acrovin 100mg injection is a painkiller.
Fact: This medicine is an antiplatelet agent used to prevent blood clots, not a painkiller.
🔄 Alternative Options
Generic Alternatives
- Tirofiban injection
Brand Alternatives
- Aggrastat