acronil 100mg capsule - Flupirtine (100mg) medicine

acronil 100mg capsule - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Consern Pharma Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is acronil 100mg capsule used for?

Acronil (Flupirtine) is used to treat PAIN ANALGESICS. It contains Flupirtine (100mg), which Selective neuronal potassium channel opener; indirect NMDA receptor antagonist. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Flupirtine
  • Manufacturer: Consern Pharma Limited
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š acronil 100mg capsule Uses & Benefits

Acute and chronic pain, muscle spasms

Off-label uses: Neuropathic pain, fibromyalgia

๐Ÿ“‹ Drug Information

Generic Name(s)Flupirtine
Brand NameAcronil
ManufacturerConsern Pharma Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassSelective neuronal potassium channel openers (SNEPCO)
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration
DistributionWidely distributed; crosses blood-brain barrier
Protein BindingApproximately 80%
MetabolismHepatic, primarily via CYP450 isoenzymes (CYP2C9, CYP2C19, CYP3A4)
Half-Life6-10 hours
ExcretionRenal (70% as metabolites, 20% unchanged)
Bioavailability90%
Onset of Action30-60 minutes
Peak Plasma Time1-2 hours
Duration of Action6-8 hours

How It Works

Selective neuronal potassium channel opener; indirect NMDA receptor antagonist

Mechanism Steps

1Opens Kv7 potassium channels in neurons
2Hyperpolarizes neuronal membrane
3Reduces neuronal excitability

๐Ÿ’ก How to Take acronil 100mg capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of acronil 100mg capsule

โœ… Common Side Effects

  • Dizziness
  • Drowsiness
  • Nausea
  • Constipation
  • Dry mouth

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Liver failure
  • Seizures
  • Allergic reactions

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased INR and bleeding risk
Alcohol Major Enhanced sedation and hepatotoxicity
CNS depressants Major Additive sedation
MAO inhibitors Major Risk of hypertensive crisis
Antihypertensives Moderate Enhanced hypotensive effect
Diuretics Moderate Increased risk of electrolyte imbalance
Oral contraceptives Moderate Reduced contraceptive efficacy
Antacids Minor Slight decrease in absorption
Cimetidine Minor Increased flupirtine levels

๐Ÿšจ Major Interactions

  • Warfarin
  • CNS depressants
  • MAO inhibitors

โšก Moderate Interactions

  • Antihypertensives
  • Diuretics
  • Oral contraceptives

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

High-fat meals may delay absorption

๐Ÿท Alcohol Interaction

Increased CNS depression and hepatotoxicity risk

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, severe hepatic impairment, history of drug-induced liver injury, pregnancy, lactation

๐Ÿ“Š Monitoring Parameters

Liver function tests (ALT, AST), renal function, blood pressure

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, supportive care; no specific antidote

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for acronil 100mg capsule

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Alternative brands with exact same active ingredient (Flupirtine (100mg)):

Medical Note: Always consult your doctor before switching medications.

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