Acronil 100mg Capsule (Flupirtine): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes (jaundice)
- Dark urine or pale stools
- Severe nausea, vomiting, or loss of appetite
- Upper abdominal pain or tenderness
- Unusual bleeding or bruising
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe dizziness or fainting
- Confusion or hallucinations
- Chest pain or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is acronil 100mg capsule used for?
This medicine contains flupirtine 100 mg, a non-opioid analgesic used for acute and chronic musculoskeletal pain. It works by opening potassium channels in nerve cells to reduce pain signals. It is taken orally 2-3 times daily with food. It can cause liver injury, so regular monitoring is needed. It is not recommended for children under 18, pregnant women, or people with liver disease.
- Generic Name: Flupirtine
- Manufacturer: Consern Pharma Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acronil 100mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा फ्लुपिर्टिन 100 मिलीग्राम कैप्सूल है, जिसका उपयोग तीव्र और दीर्घकालिक दर्द के इलाज के लिए किया जाता है, विशेष रूप से मांसपेशियों और जोड़ों के दर्द, कमर दर्द और ऑस्टियोआर्थराइटिस में। यह दर्द को कम करने और मांसपेशियों को आराम देने में मदद करती है। यह दवा मस्तिष्क और रीढ़ की हड्डी में दर्द के संकेतों को कम करके काम करती है। इसे भोजन के साथ लेना चाहिए। यह दवा लीवर को नुकसान पहुंचा सकती है, इसलिए डॉक्टर की सलाह के बिना लंबे समय तक न लें। गर्भवती महिलाओं, स्तनपान कराने वाली महिलाओं, 18 वर्ष से कम बच्चों और लीवर की बीमारी वाले लोगों को यह दवा नहीं लेनी चाहिए। शराब के साथ इसका सेवन बिल्कुल न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, नींद आना, मुंह सूखना, जी मिचलाना, उल्टी, कब्ज, थकान और सिरदर्द शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभावों में लीवर की क्षति के लक्षण जैसे आंखों या त्वचा का पीला पड़ना, गहरे रंग का मूत्र, गंभीर जी मिचलाना, भूख न लगना या पेट के ऊपरी हिस्से में दर्द शामिल हैं। अगर आपको एलर्जी की प्रतिक्रिया जैसे दाने, खुजली, चेहरे, होंठ या गले में सूजन या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। शराब का सेवन बिल्कुल न करें। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह दवा आप पर कैसे असर करती है। दवा को भोजन के साथ लें। डॉक्टर की सलाह के बिना दवा की खुराक या अवधि न बढ़ाएं। लीवर की कार्यप्रणाली की नियमित जांच कराएं। अगर आपको पीलिया, गहरे रंग का मूत्र या पेट में गंभीर दर्द हो, तो दवा बंद करें और तुरंत डॉक्टर से मिलें।
💊 acronil 100mg capsule Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"This medicine is used for short-term relief of acute pain from muscle strains, sprains, and other musculoskeletal injuries.","evidence":"Well-established"},{"condition":"Chronic low back pain","description":"It helps reduce chronic back pain and associated muscle spasms, improving daily function.","evidence":"Moderate"},{"condition":"Osteoarthritis pain","description":"This medicine can relieve pain and improve mobility in patients with osteoarthritis of the knee, hip, or hand.","evidence":"Moderate"},{"condition":"Postoperative pain","description":"It may be used for short-term management of mild to moderate postoperative pain.","evidence":"Limited"},{"condition":"Tension headache","description":"Sometimes prescribed for tension-type headaches, though evidence is limited.","evidence":"Limited"}]
Off-label uses: [{"condition":"Fibromyalgia","description":"Occasionally used off-label for fibromyalgia pain, but evidence is insufficient.","evidence":"Limited"},{"condition":"Neuropathic pain","description":"Rarely used off-label for certain neuropathic pain conditions, but not first-line.","evidence":"Limited"}]
Primary treatment for: Musculoskeletal pain
Also treats: Low back pain, Osteoarthritis, Postoperative pain, Tension headache
📋 Drug Information
| Generic Name(s) | Flupirtine |
| Brand Name | Acronil |
| Manufacturer | Consern Pharma Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Selective neuronal potassium channel openers (SNEPCO) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture, heat, and direct sunlight. Do not refrigerate unless specified. Keep in the original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by opening potassium channels in neuronal cells, which leads to stabilization of the resting membrane potential and inhibition of neuronal excitability. This reduces the transmission of pain signals along the nervous system. Additionally, it indirectly modulates the descending pain pathways and may interact with NMDA receptors, contributing to its analgesic and muscle relaxant effects. Unlike opioids, it does not bind to opioid receptors, and unlike NSAIDs, it does not inhibit cyclooxygenase enzymes, which means it has a different side effect profile.
Mechanism Steps
💡 How to Take acronil 100mg capsule
Strength: Flupirtine 100 mg immediate-release capsule
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 100 mg taken orally two to three times daily, depending on the severity of pain and your doctor's assessment. The maximum recommended daily dose is 300 mg. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. Take with food to reduce stomach upset. The duration of treatment should be as short as possible, typically not exceeding 2 weeks without medical review. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This medicine is not recommended for children under 18 years of age. Consult a pediatrician for alternative pain management options. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially dizziness, drowsiness, and liver toxicity. Dose adjustment may be necessary based on liver and kidney function. Use with caution and monitor closely. |
| Renal Impairment | In patients with mild to moderate renal impairment, dose adjustment may not be necessary, but caution is advised. In severe renal impairment (creatinine clearance <30 mL/min), this medicine is contraindicated. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | This medicine is contraindicated in patients with pre-existing liver disease or elevated liver enzymes. In patients with mild hepatic impairment, use with extreme caution and monitor liver function closely. Dose reduction may be required. Avoid in moderate to severe hepatic impairment. |
| Maximum Daily Dose | 300 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acronil 100mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Paracetamol (high dose) | Major | |
| Benzodiazepines | Major | |
| Alcohol | Major | |
| Carbamazepine | Moderate | |
| Antihypertensives | Moderate | |
| Antacids | Minor | |
| Methotrexate | Major | |
| Isoniazid | Major | |
| Rifampicin | Moderate |
🚨 Major Interactions
- Other hepatotoxic drugs (e.g., paracetamol, methotrexate, isoniazid)
- Central nervous system depressants (e.g., benzodiazepines, opioids, alcohol)
⚡ Moderate Interactions
- Warfarin
- Antihypertensive drugs
- Carbamazepine
🍷 Alcohol Interaction
Alcohol should be strictly avoided while taking this medicine because it can increase the risk of liver damage and enhance central nervous system depression, leading to excessive drowsiness, dizziness, and impaired coordination.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to flupirtine or any component of the formulation","Pre-existing liver disease or elevated liver enzymes","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["This medicine can cause liver injury. Regular monitoring of liver function is essential.","Avoid alcohol completely during treatment.","May cause drowsiness and dizziness. Do not drive or operate machinery until you know how it affects you.","Do not exceed the recommended dose or duration of treatment.","Use with caution in elderly patients and those with kidney impairment.","Do not use for longer than 2 weeks without medical supervision.","Inform your doctor if you have a history of liver or kidney disease.","Discontinue immediately if you experience symptoms of liver injury.","Not recommended for children under 18 years.","May interact with other medications; inform your doctor about all medicines you take."]
🤱 Lactation Safety
This medicine is excreted in breast milk. Breastfeeding is not recommended while taking this medicine. Consult your doctor for alternative options.
💊 Overdose Management
Overdose of this medicine may cause severe drowsiness, dizziness, nausea, vomiting, and potentially liver damage. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if taken recently. Monitor liver function and vital signs closely.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have any liver or kidney problems, as dose adjustments may be needed. Do not consume alcohol while taking this medicine, as it can increase the risk of liver damage and drowsiness. Avoid driving or operating heavy machinery until you know how this medicine affects you. Take this medicine with food to reduce stomach upset. Do not take this medicine for longer than prescribed, as prolonged use can increase the risk of liver toxicity. Your doctor may perform regular blood tests to check your liver function. If you experience symptoms like yellowing of the eyes or skin, dark urine, or severe abdominal pain, stop the medicine and seek medical help immediately. Do not share this medicine with others, even if they have similar symptoms. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are more susceptible to the side effects of this medicine, particularly dizziness, drowsiness, and liver toxicity. Dose adjustment may be necessary based on liver and kidney function. Regular monitoring of liver function is recommended. Use with caution and avoid activities requiring mental alertness until you know how the medicine affects you.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended for use during pregnancy or if you are planning to become pregnant. It may harm the developing fetus. If you are planning pregnancy, consult your doctor to discuss alternative pain management options that are safe for pregnancy.
🏥 Post-Surgery Considerations
This medicine may be used for short-term postoperative pain management. However, it should be used with caution, especially if you have had surgery involving the liver or kidneys. Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with other medications used during surgery.
🦷 Dental Procedures
If you are scheduled for dental procedures, inform your dentist that you are taking this medicine. It may interact with anesthetics or other medications used during dental work. Your dentist may need to adjust your treatment plan. Do not stop taking this medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid activities that require mental alertness, such as driving or operating heavy machinery, until you know how the medicine affects you. If you exercise, do so with caution and stop if you feel dizzy or unwell. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, and fatigue, which can affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job involves such tasks. Take frequent breaks if you have a desk job and maintain good posture.
🛑 When to Stop This Medicine
You should stop taking this medicine and consult your doctor immediately if you experience any signs of liver injury, such as yellowing of the skin or eyes, dark urine, severe nausea, or upper abdominal pain. Also stop if you have a severe allergic reaction. Do not stop the medicine abruptly without consulting your doctor, as withdrawal symptoms may occur. Your doctor will advise you on the appropriate duration of treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to the risk of liver toxicity, which can be serious. Prolonged use may also lead to tolerance, dependence, and withdrawal symptoms upon discontinuation. Regular monitoring of liver function is essential if extended use is necessary. Other potential long-term effects include kidney impairment and blood disorders. It is important to use this medicine only for the shortest duration necessary and under close medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedMay help relieve certain types of pain, but evidence is mixed.
Evidence: ModerateHelps manage chronic pain by changing thought patterns and behaviors.
Evidence: ModerateCreams or gels applied to the skin can provide localized pain relief with fewer systemic side effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a vaccine, inform your healthcare provider that you are taking this medicine. It is generally safe to continue taking it unless your doctor advises otherwise.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust your dosing schedule gradually, but consult your doctor first. Check local customs regulations regarding prescription medicines. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking a dose. The peak effect occurs in about 1.5 to 2 hours.
A: Yes, it is recommended to take this medicine with food to reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is not recommended for long-term use due to the risk of liver toxicity. It should be used for the shortest duration possible, usually not exceeding 2 weeks without medical review.
A: No, alcohol should be strictly avoided as it increases the risk of liver damage and drowsiness.
A: This medicine is not recommended during pregnancy. Consult your doctor for alternative pain management options.
A: Yes, this medicine can cause liver injury. Regular monitoring of liver function tests is recommended during treatment. Discontinue immediately if you notice signs of liver problems.
A: You should consult your doctor before combining this medicine with other painkillers, especially those that can affect the liver, such as paracetamol.
🤔 Common Patient Concerns
🔄 Substitutes for acronil 100mg capsule
View AllAlternative brands with exact same active ingredient:
-
flupixa 100mg capsuleAjanta Pharma Ltd ₹60.94 27.8% CHEAPER
-
fluvista 100 mg capsuleZuventus Healthcare Ltd ₹61.76 26.8% CHEAPER
-
Flupilib 100mg CapsuleAlbia Biocare ₹64.69 23.3% CHEAPER
-
dolpiritin 100mg tabletMicro Labs Ltd ₹65.50 22.4% CHEAPER
-
flit 100mg capsuleSigmund Promedica ₹65.63 22.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a safe alternative to all other painkillers.
Fact: This medicine carries a risk of serious liver injury and is not suitable for everyone. It should only be used under medical supervision. - Myth: You can take this medicine for as long as you want.
Fact: Prolonged use increases the risk of liver toxicity. Treatment should be as short as possible, usually not exceeding 2 weeks without medical review. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol should be strictly avoided as it increases the risk of liver damage and drowsiness. - Myth: This medicine is safe for children.
Fact: This medicine is not recommended for children under 18 years of age.
🔄 Alternative Options
Generic Alternatives
- Flupirtine 100 mg capsule
Brand Alternatives
- Acronil 100mg capsule