acris 10mg/ml injection - Atracurium (10mg/ml) medicine

Acris 10mg/ml Injection - Uses, Price, Side Effects

4.7 (14 reviews)
๐Ÿญ Gland Pharma Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿคฐ Pregnancy Category C ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is acris 10mg/ml injection used for?

Acris 10mg/ml Injection contains Atracurium, a neuromuscular blocking agent used to relax muscles during surgery or mechanical ventilation. It works by blocking nerve impulses at the neuromuscular junction, causing temporary paralysis. It is administered intravenously by healthcare professionals.

  • Generic Name: Atracurium besilate
  • Manufacturer: Gland Pharma Limited
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š acris 10mg/ml injection Uses & Benefits

Adjunct to general anesthesia for skeletal muscle relaxation; facilitation of endotracheal intubation; mechanical ventilation

Off-label uses: Status epilepticus (rarely used)

๐Ÿ“‹ Drug Information

Generic Name(s)Atracurium besilate
Brand NameAtracurium Besilate Injection
ManufacturerGland Pharma Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassSkeletal muscle relaxant- Peripherally acting
Route of AdministrationIntravenous (IV)
StorageRefrigerate at 2-8ยฐC; protect from light; do not freeze
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionNot applicable (IV administration)
DistributionWidely distributed; crosses placenta minimally
Protein Binding82%
MetabolismHofmann elimination (non-enzymatic) and ester hydrolysis
Half-Life20 minutes
ExcretionRenal (10-40% unchanged) and biliary
Bioavailability100% (IV)
Onset of Action2-3 minutes
Peak Plasma TimeImmediately after IV bolus
Duration of Action20-35 minutes

How It Works

Competitive antagonist at nicotinic acetylcholine receptors at the neuromuscular junction

Mechanism Steps

1Atracurium binds competitively to nicotinic acetylcholine receptors at the motor end-plate
2Prevents acetylcholine from binding and depolarizing the muscle membrane
3Inhibits muscle contraction, resulting in skeletal muscle paralysis

๐Ÿ’ก How to Take acris 10mg/ml injection

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of acris 10mg/ml injection

โœ… Common Side Effects

  • Hypotension
  • Flushing
  • Bradycardia
  • Skin rash

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Bronchospasm
  • Prolonged neuromuscular blockade
  • Respiratory depression

โš ๏ธ Rare Side Effects

  • Myopathy
  • Histamine release reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Aminoglycosides Major Increased neuromuscular blockade
Inhalational anesthetics Moderate Enhanced muscle relaxation
Succinylcholine Major Prolonged apnea

๐Ÿšจ Major Interactions

  • Aminoglycosides
  • Polymyxins
  • Magnesium sulfate
  • Lithium
  • Quinidine
  • Procainamide

โšก Moderate Interactions

  • Inhalational anesthetics
  • Succinylcholine
  • Calcium channel blockers
  • Diuretics

โ„น๏ธ Minor Interactions

  • Corticosteroids
  • Phenytoin
  • Carbamazepine

๐Ÿท Alcohol Interaction

No specific interaction

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Moderate
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to atracurium or bisbenzylisoquinolinium compounds

๐Ÿ“Š Monitoring Parameters

Neuromuscular function (train-of-four monitoring); vital signs; respiratory status

๐Ÿคฑ Lactation Safety

Unknown; use with caution

๐Ÿ’Š Overdose Management

Supportive care; neostigmine or other anticholinesterases with atropine to reverse blockade; mechanical ventilation if needed

โฐ Missed Dose

Not applicable (administered by healthcare professional)

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for acris 10mg/ml injection

View All

Alternative brands with exact same active ingredient (Atracurium (10mg/ml)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

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