acred plus 50mg/500mg tablet - Aceclofenac (50mg) + Paracetamol (500mg) medicine

ASR P 50mg/500mg Tablet: Complete Medicine Guide

No reviews yet
🏭 Redson Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Use only if clearly needed and prescribed by a doctor. Avoid in the third trimester due to risk of premature closure of ductus arteriosus. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term pain relief.
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is acred plus 50mg/500mg tablet used for?

This medicine is a combination of Aceclofenac 50 mg and Paracetamol 500 mg used for short-term relief of pain and inflammation. It is taken orally with food, usually every 8-12 hours, not exceeding 3 tablets in 24 hours. It should be avoided in patients with stomach ulcers, severe kidney or liver disease, and during the third trimester of pregnancy.

  • Generic Name: Aceclofenac + Paracetamol
  • Manufacturer: Redson Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 acred plus 50mg/500mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एसिटाक्लोफेनाक 50 मिलीग्राम और पैरासिटामोल 500 मिलीग्राम का संयोजन है। इसका उपयोग दर्द और सूजन से राहत के लिए किया जाता है, जैसे कि जोड़ों का दर्द, मांसपेशियों का दर्द, दांत का दर्द, मासिक धर्म में ऐंठन, और सर्जरी के बाद का दर्द। यह दवा सूजन को कम करने और दर्द को शांत करने में मदद करती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, एलर्जी प्रतिक्रिया, लीवर या किडनी की समस्या शामिल हो सकती है। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खाली पेट न लें, भोजन के साथ लें। शराब का सेवन न करें। अन्य दर्द निवारक दवाओं के साथ न लें। यदि आपको पेट अल्सर, किडनी या लीवर की बीमारी है तो डॉक्टर को बताएं। 7 दिनों से अधिक इसका उपयोग न करें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 acred plus 50mg/500mg tablet Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces pain and inflammation in rheumatoid arthritis as an adjunct to disease-modifying therapy.","evidence":"Well-established"},{"condition":"Acute musculoskeletal pain","description":"Provides relief from acute pain due to sprains, strains, and other soft tissue injuries.","evidence":"Well-established"},{"condition":"Dental pain","description":"Effective for short-term relief of dental pain, including post-extraction pain.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for the management of mild to moderate post-operative pain.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Fever","description":"Paracetamol component may reduce fever, but this combination is not primarily indicated for fever alone.","evidence":"Limited"}]

Primary treatment for: Pain and inflammation

Also treats: Osteoarthritis, Rheumatoid arthritis, Dental pain, Post-operative pain, Dysmenorrhea

📋 Drug Information

Generic Name(s)Aceclofenac + Paracetamol
Brand NameAldigesic P
ManufacturerRedson Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Do not exceed the recommended dose of 3 tablets in 24 hours.
3
Avoid alcohol while taking this medicine to prevent liver damage and gastrointestinal bleeding.
4
Consult your doctor if pain persists beyond 7 days or worsens.
5
Inform your doctor about all other medicines you are taking, especially blood thinners.
6
Report any unusual bleeding, bruising, or yellowing of eyes immediately.
7
Use the lowest effective dose for the shortest duration, especially if you are elderly.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Dental pain
This medicine can provide short-term relief for dental pain.
Likely Use
Menstrual cramps
This medicine is effective for dysmenorrhea.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAceclofenac is rapidly absorbed after oral administration. Paracetamol is also rapidly and completely absorbed from the gastrointestinal tract. Food may delay the absorption of both components but does not significantly reduce the extent of absorption.
DistributionBoth Aceclofenac and Paracetamol are widely distributed throughout the body. Aceclofenac is highly protein-bound, while Paracetamol distributes into most body fluids and tissues.
Protein BindingAceclofenac is approximately 99% bound to plasma proteins. Paracetamol is only about 10-25% bound to plasma proteins.
MetabolismAceclofenac is metabolized in the liver primarily by cytochrome P450 enzymes, mainly CYP2C9, to inactive metabolites. Paracetamol is metabolized in the liver via glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeThe elimination half-life of Aceclofenac is approximately 4-6 hours. Paracetamol has a half-life of about 2-3 hours.
ExcretionAceclofenac metabolites are excreted mainly in urine and bile. Paracetamol metabolites are excreted primarily in urine.
BioavailabilityThe oral bioavailability of Aceclofenac is approximately 80-100%. Paracetamol has an oral bioavailability of about 80-90%.
Onset of ActionPain relief typically begins within 30-60 minutes after oral administration.
Peak Plasma TimeAceclofenac reaches peak plasma concentration in about 1.5-2 hours. Paracetamol peaks in about 0.5-1 hour.
Duration of ActionThe analgesic effect lasts approximately 4-6 hours, requiring dosing every 8-12 hours as prescribed.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, leading to decreased synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, producing analgesic and antipyretic effects with minimal anti-inflammatory action. Together, they provide enhanced pain relief through different pathways.

Mechanism Steps

1
Aceclofenac absorption and distribution: After oral administration, Aceclofenac is absorbed and distributed to inflamed tissues.
2
COX enzyme inhibition: Aceclofenac inhibits COX-1 and COX-2 enzymes, reducing prostaglandin synthesis.
3
Reduced inflammation and pain: Decreased prostaglandins lead to reduced inflammation, swelling, and pain perception.
4
Paracetamol central action: Paracetamol acts on the central nervous system to inhibit prostaglandin synthesis and modulate pain pathways.
5
Additive analgesic effect: The combined actions of Aceclofenac and Paracetamol result in enhanced pain relief.

💡 How to Take acred plus 50mg/500mg tablet

Strength: Tablet containing Aceclofenac 50 mg and Paracetamol 500 mg.

1Take this medicine orally with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow the prescribed dose and duration exactly.
5Do not take more than 3 tablets in 24 hours.
6If you miss a dose, take it as soon as you remember, but skip if it's almost time for the next dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally every 8 to 12 hours as needed for pain, not exceeding three tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Take with food or milk to reduce stomach upset.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentUse with caution in patients with kidney impairment. Dose reduction may be necessary. Consult your doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose reduction may be necessary. Consult your doctor for individualized dosing.
Maximum Daily DoseMaximum daily dose is 3 tablets (Aceclofenac 150 mg + Paracetamol 1500 mg) in 24 hours. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage and gastrointestinal bleeding.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of acred plus 50mg/500mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Stomach pain (Common (5-10%))
Take with food. Avoid alcohol. If severe, contact your doctor.
Indigestion (Common (5-10%))
Take with food. Antacids may help, but consult your doctor first.
Headache (Common (5-10%))
Usually resolves on its own. If persistent, consult your doctor.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Uncommon (1-5%))
Avoid driving or operating machinery. Consult your doctor if it persists.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, or throat, difficulty breathing, or rash.
Liver damage (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.
Kidney impairment (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor.
Cardiovascular events (Rare (<0.1%))
Seek immediate care for chest pain, shortness of breath, or weakness.

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Seek emergency care for rash, blisters, or peeling skin.
Agranulocytosis
Report fever, sore throat, or unusual tiredness to your doctor.
Pancreatitis
Seek immediate care for severe abdominal pain radiating to the back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Other NSAIDs Major
Corticosteroids Major
ACE inhibitors Major
Diuretics Moderate
Lithium Moderate
SSRIs Moderate
Antihypertensives Moderate
Zidovudine Moderate

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Other NSAIDs
  • Corticosteroids
  • ACE inhibitors and ARBs

⚡ Moderate Interactions

  • Diuretics
  • Lithium
  • SSRIs
  • Antihypertensives
  • Zidovudine

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage, especially from Paracetamol, and increases the risk of gastrointestinal bleeding from Aceclofenac.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Aceclofenac, Paracetamol, or any component of the formulation.","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.","Active peptic ulcer or gastrointestinal bleeding.","Severe heart failure, severe kidney impairment, or severe liver impairment.","Third trimester of pregnancy.","Children under 14 years of age (unless directed by a pediatrician)."]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose or duration.","Use with caution in elderly patients due to increased risk of side effects.","Inform your doctor if you have a history of stomach ulcers, kidney disease, liver disease, or heart disease.","Do not take other pain relievers or NSAIDs without consulting your doctor.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Stop use and consult a doctor if you experience signs of allergic reaction, gastrointestinal bleeding, or liver problems."]

🤱 Lactation Safety

Aceclofenac and Paracetamol are excreted in breast milk in small amounts. Consult your doctor before use during breastfeeding. Short-term use may be considered if benefits outweigh risks.

💊 Overdose Management

Overdose can cause severe liver damage, especially due to Paracetamol. Symptoms may include nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment may include activated charcoal, N-acetylcysteine for Paracetamol toxicity, and supportive care. Do not induce vomiting unless instructed by a healthcare professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of liver damage and gastrointestinal bleeding. Do not take other pain relievers or NSAIDs without consulting your doctor. If you have a history of stomach ulcers, kidney disease, liver disease, or heart disease, inform your doctor before taking this medicine. Do not use this medicine for more than 7 days without medical advice. Keep out of reach of children. Store at room temperature away from direct sunlight and moisture.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy if you are taking this medicine. It is not recommended during pregnancy, especially in the third trimester.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain relief. However, it may increase the risk of bleeding. Consult your surgeon before taking it after surgery.

🦷 Dental Procedures

This medicine can be used for dental pain relief. Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Stay well hydrated.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may increase pain while taking this medicine. Gentle stretching and low-impact exercises are recommended. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated
Eat plenty of fruits and vegetables

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may affect your ability to perform tasks requiring alertness.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or liver problems. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver damage, and cardiovascular events. Regular monitoring of liver and kidney function is advised. Use the lowest effective dose for the shortest duration. Consult your doctor for periodic reviews.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Hot and cold therapy

May help reduce pain and inflammation.

Evidence: Limited
Acupuncture

Some evidence for pain relief in chronic conditions.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established. However, consult your doctor before vaccination if you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Declare it at customs if required. Keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 30-year-old woman with severe menstrual cramps
Used this medicine for dysmenorrhea and experienced relief within an hour. She was advised to take it with food and not to exceed the recommended dose.
💡 Lesson: This medicine can provide effective short-term relief for menstrual pain when taken as directed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief typically begins within 30-60 minutes after taking this medicine.

Q: Can I take this medicine on an empty stomach?

A: It is best to take this medicine with food or milk to reduce stomach upset.

Q: Is it safe to take this medicine with other pain relievers?

A: Do not take other NSAIDs or pain relievers without consulting your doctor, as it may increase the risk of side effects.

Q: Can I take this medicine if I am pregnant?

A: Consult your doctor before taking this medicine during pregnancy. It is not recommended in the third trimester.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for acred plus 50mg/500mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure arthritis.
    Fact: This medicine provides symptomatic relief but does not cure arthritis. It should be used as part of a comprehensive treatment plan.
  • Myth: It is safe to take this medicine without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under medical supervision.
  • Myth: Taking more than the recommended dose will relieve pain faster.
    Fact: Taking more than the recommended dose increases the risk of serious side effects and does not provide faster relief.

🔄 Alternative Options

Generic Alternatives

  • Aceclofenac 50 mg + Paracetamol 500 mg tablet (generic)

Brand Alternatives

  • ASR P 50mg/500mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Aceclofenac 50 mg + Paracetamol 500 mg","strength":"50mg + 500mg","dosage_form":"Tablet","route":"Oral"},{"medicine":"Aceclofenac 100 mg + Paracetamol 325 mg","composition":"Aceclofenac 100 mg + Paracetamol 325 mg","strength":"100mg + 325mg","dosage_form":"Tablet","route":"Oral"},{"medicine":"Diclofenac 50 mg + Paracetamol 500 mg","composition":"Diclofenac 50 mg + Paracetamol 500 mg","strength":"50mg + 500mg","dosage_form":"Tablet","route":"Oral"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory