aconix-jr tablet dt - Aceclofenac (50mg) + Paracetamol (250mg) medicine

Aconix-JR Tablet DT: Complete Medicine Guide

No reviews yet
🏭 Medinix Pharmaceutical Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Use only if clearly needed and prescribed by a doctor. Avoid in third trimester due to risk of premature closure of ductus arteriosus. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for symptomatic relief of pain and fever.
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is aconix-jr tablet dt used for?

This medicine is a combination of Aceclofenac 50 mg and Paracetamol 250 mg used for short-term relief of pain, inflammation, and fever. It works by reducing prostaglandins that cause pain and swelling. Take it with food, avoid alcohol, and do not exceed 4 tablets in 24 hours.

  • Generic Name: Aceclofenac (50mg) + Paracetamol (250mg)
  • Manufacturer: Medinix Pharmaceutical Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 aconix-jr tablet dt के बारे में (Hindi Summary)

उपयोग: यह दवा एसिटोक्लोफेनाक 50 मिलीग्राम और पैरासिटामोल 250 मिलीग्राम का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द, सूजन और बुखार के इलाज के लिए किया जाता है। यह मांसपेशियों के दर्द, दांत दर्द, सिरदर्द और बुखार में राहत देती है। इसे भोजन के साथ लें और शराब से बचें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, एलर्जी, लीवर और किडनी की समस्या हो सकती है। कोई भी गंभीर लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें। यदि आपको पेट अल्सर, किडनी या लीवर की बीमारी, हृदय रोग या अस्थमा है तो डॉक्टर को बताएं। 7 दिनों से अधिक इसका उपयोग बिना डॉक्टर की सलाह के न करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 aconix-jr tablet dt Uses & Benefits

[{"condition":"Musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as back pain, muscle sprains, and strains.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Headache","description":"Effective for tension-type headaches and mild migraines.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever due to the Paracetamol component.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after minor surgeries.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label for preventing migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used for menstrual cramps, though not a first-line treatment.","evidence":"Limited"}]

Primary treatment for: Pain and inflammation

Also treats: Fever, Musculoskeletal pain, Dental pain, Headache

📋 Drug Information

Generic Name(s)Aceclofenac (50mg) + Paracetamol (250mg)
Brand Nameaconix-jr tablet dt
ManufacturerMedinix Pharmaceutical Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce stomach upset.
2
Do not exceed the recommended dose of 4 tablets in 24 hours.
3
Avoid alcohol while taking this medicine to prevent liver damage and gastrointestinal bleeding.
4
If you have a history of stomach ulcers, kidney or liver disease, inform your doctor before taking this medicine.
5
Do not use this medicine for more than 7 days without consulting your doctor.
6
Report any unusual bleeding, bruising, or yellowing of skin to your doctor immediately.
7
Stay well hydrated while taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
✅
Fever
This medicine contains Paracetamol which reduces fever.
Likely Use
✅
Dental pain
This medicine is effective for dental pain.
Likely Use
✅
Headache
This medicine can relieve tension headaches.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAceclofenac is rapidly absorbed after oral administration, with peak plasma concentrations reached in about 1.25 to 3 hours. Paracetamol is also rapidly absorbed, with peak levels occurring within 0.5 to 2 hours. Food may delay absorption slightly but does not significantly affect the extent of absorption.
DistributionAceclofenac is highly protein-bound (greater than 99%) and distributes well into synovial fluid. Paracetamol distributes widely throughout body fluids, with a volume of distribution of about 0.95 L/kg.
Protein BindingAceclofenac is approximately 99.7% bound to plasma proteins. Paracetamol is about 10-25% bound to plasma proteins.
MetabolismAceclofenac is metabolized in the liver primarily by CYP2C9 to 4'-hydroxyaceclofenac and other metabolites. Paracetamol is metabolized in the liver via glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeThe elimination half-life of Aceclofenac is approximately 4 hours. Paracetamol has a half-life of about 2 to 3 hours.
ExcretionAceclofenac metabolites are excreted mainly in urine and bile. Paracetamol metabolites are excreted primarily in urine.
BioavailabilityThe oral bioavailability of Aceclofenac is nearly 100%. Paracetamol has an oral bioavailability of about 80-90%.
Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration.
Peak Plasma TimeAceclofenac peak plasma concentration occurs at 1.25 to 3 hours. Paracetamol peak plasma concentration occurs at 0.5 to 2 hours.
Duration of ActionThe analgesic effect lasts approximately 4 to 6 hours, requiring dosing every 6 to 8 hours as needed.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, leading to decreased synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, resulting in analgesia and antipyresis. Together, they provide enhanced pain relief and anti-inflammatory effects.

Mechanism Steps

1
Inhibition of cyclooxygenase enzymes: Aceclofenac inhibits COX-1 and COX-2 enzymes, reducing the conversion of arachidonic acid to prostaglandins.
2
Reduced prostaglandin synthesis: Decreased prostaglandin levels lead to less inflammation, pain, and fever.
3
Central analgesic action of Paracetamol: Paracetamol acts on the central nervous system to inhibit prostaglandin synthesis and modulate pain perception.
4
Combined symptomatic relief: The additive effects provide better pain relief than either agent alone.

💡 How to Take aconix-jr tablet dt

Strength: Dispersible tablet containing Aceclofenac 50 mg and Paracetamol 250 mg.

1Disperse the tablet in a glass of water (about 100 mL) and stir until dissolved.
2Drink the solution immediately.
3Take with food or milk to reduce stomach upset.
4Do not chew or swallow the tablet whole if it is a dispersible tablet; always disperse in water first.
5Follow the dosage schedule prescribed by your doctor.
6Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet (Aceclofenac 50 mg + Paracetamol 250 mg) taken orally every 6 to 8 hours as needed for pain and fever. Do not exceed 4 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Take with food or milk to reduce stomach upset. Use for the shortest duration necessary.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of NSAIDs and Paracetamol. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely.
Renal ImpairmentUse with caution in patients with renal impairment. Dose reduction may be necessary. Avoid in severe renal impairment (creatinine clearance <30 mL/min). Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction may be necessary. Avoid in severe hepatic impairment. Monitor liver function tests.
Maximum Daily DoseMaximum daily dose is 4 tablets (Aceclofenac 200 mg + Paracetamol 1000 mg) in 24 hours. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and risk of ulcers.
Alcohol
Avoid
Increases risk of liver damage and gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of aconix-jr tablet dt

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Stomach pain (Common (5-10%))
Take with food. Avoid alcohol. If severe, seek medical advice.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult if severe.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Uncommon (1-5%))
Avoid activities requiring alertness. Consult if persistent.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black, tarry stools, vomiting blood, or severe abdominal pain.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, throat, difficulty breathing, or rash.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.
Kidney impairment (Rare (<0.1%))
Notify your doctor if you notice decreased urine output or swelling in legs.

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Seek immediate medical attention if you develop a painful rash with blisters or peeling skin.
Agranulocytosis
Report sudden fever, sore throat, or mouth ulcers to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Other NSAIDs Major
ACE inhibitors Moderate
Diuretics Moderate
Corticosteroids Moderate
Antacids Minor
Cholestyramine Minor

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Other NSAIDs

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Corticosteroids

🍷 Alcohol Interaction

Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of liver damage, especially due to the Paracetamol component, and can also increase the risk of gastrointestinal bleeding from Aceclofenac.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Aceclofenac, Paracetamol, or any other NSAID.","Active or history of peptic ulcer or gastrointestinal bleeding.","Severe heart failure, severe kidney disease, or severe liver disease.","Third trimester of pregnancy.","Children under 12 years of age.","Asthma, urticaria, or allergic reactions after taking aspirin or other NSAIDs."]

⚠️ Warnings & Precautions

["Take with food to minimize stomach upset.","Avoid alcohol consumption.","Do not exceed recommended dose or duration.","Use with caution in elderly patients.","Monitor liver and kidney function with long-term use.","Discontinue if signs of gastrointestinal bleeding occur.","Not recommended for patients with bleeding disorders.","May impair ability to drive or operate machinery."]

🤱 Lactation Safety

Aceclofenac and Paracetamol are excreted in breast milk in small amounts. Consult your doctor before use during breastfeeding. Short-term use may be considered if benefits outweigh risks.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, abdominal pain, liver damage, and kidney failure. Seek immediate medical attention. Treatment is supportive and symptomatic. For Paracetamol overdose, N-acetylcysteine is the antidote and should be administered as soon as possible. Activated charcoal may be given if within 1-2 hours of ingestion.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of liver damage and gastrointestinal bleeding. Do not take other medicines containing Paracetamol or NSAIDs without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. Do not use this medicine for more than 7 days without medical advice. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. NSAIDs may affect ovulation and are generally avoided in the third trimester.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain under medical supervision. Inform your surgeon if you are taking this medicine before surgery, as it may increase bleeding risk.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk. It can also be used for dental pain relief as prescribed.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Engage in regular low-impact exercise like walking or swimming.
😴
Practice good posture to prevent musculoskeletal pain.
💧
Include anti-inflammatory foods like fruits, vegetables, and omega-3 fatty acids in your diet.
🧘
Get adequate sleep to aid recovery.
🌞
Stay hydrated throughout the day.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you have musculoskeletal pain. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods like fish, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Stay well hydrated by drinking plenty of water.
Avoid alcohol consumption.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe for office work, but take breaks and stay hydrated.

🛑 When to Stop This Medicine

Stop taking this medicine if your pain or fever resolves, or after the prescribed duration. Do not stop abruptly if you have been on long-term therapy without consulting your doctor. Seek medical advice if symptoms persist beyond 7 days.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of liver and kidney function is recommended. Use the lowest effective dose for the shortest duration possible.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve mobility.

Evidence: Well-established
Hot/cold compresses

May help reduce localized pain and inflammation.

Evidence: Moderate
Acupuncture

Some evidence for pain relief in certain conditions.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing intervals as advised by your doctor. Keep it in your carry-on luggage to avoid extreme temperatures. Check customs regulations for carrying medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old office worker with acute back pain
Ravi, a 35-year-old software engineer, developed severe back pain after lifting heavy boxes. His doctor prescribed this medicine. He took it with food as advised and noticed significant relief within an hour. He was careful not to exceed the dose and avoided alcohol. After 3 days, his pain subsided, and he stopped the medicine.
💡 Lesson: Taking this medicine with food and adhering to the prescribed dose provides effective pain relief while minimizing stomach upset.
👤 A 28-year-old woman with dental pain
Priya had a toothache and was prescribed this medicine before a root canal. She took it as directed and experienced relief from pain and swelling. She made sure to take it with meals and avoided taking additional Paracetamol. She completed the short course without any side effects.
💡 Lesson: This medicine is effective for dental pain when taken as prescribed, and avoiding duplicate Paracetamol prevents liver risk.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best to take this medicine with food or milk to reduce the risk of stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take other NSAIDs or Paracetamol-containing products without consulting your doctor, as it may increase the risk of side effects.

Q: Can I take it during pregnancy?

A: Consult your doctor before taking this medicine during pregnancy. It is generally avoided in the third trimester.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for aconix-jr tablet dt

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is completely safe for long-term use.
    Fact: Long-term use can cause liver and kidney damage, and increase cardiovascular risk. Use only as prescribed for short durations.
  • Myth: It is okay to take extra doses if pain is severe.
    Fact: Exceeding the recommended dose can lead to serious liver damage and gastrointestinal bleeding. Always follow the prescribed dose.
  • Myth: This medicine can be taken on an empty stomach.
    Fact: It should be taken with food or milk to reduce stomach upset and risk of ulcers.

🔄 Alternative Options

Generic Alternatives

  • Aceclofenac 50 mg + Paracetamol 250 mg dispersible tablet (generic)

Brand Alternatives

  • Aconix-JR Tablet DT

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Aceclofenac 50 mg + Paracetamol 250 mg)","strength":"50 mg + 250 mg","form":"Dispersible tablet","onset":"30-60 minutes","duration":"4-6 hours"},{"medicine":"Aceclofenac 100 mg + Paracetamol 325 mg","strength":"100 mg + 325 mg","form":"Tablet","onset":"30-60 minutes","duration":"4-6 hours"},{"medicine":"Ibuprofen 200 mg + Paracetamol 325 mg","strength":"200 mg + 325 mg","form":"Tablet","onset":"30-60 minutes","duration":"4-6 hours"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory