acphyllin 100mg capsule - Acebrophylline (100mg) medicine

Acphyllin 100mg Capsule - Uses, Price, Side Effects

4.7 (16 reviews)

Acebrophylline (100mg)

🏭 Ethics Health Care Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is acphyllin 100mg capsule used for?

Acphyllin 100mg capsule contains Acebrophylline, a mucolytic and bronchodilator used to treat respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). It works by thinning mucus and relaxing airway muscles, making breathing easier. It is typically taken twice daily.

Generic Name: Acebrophylline
Manufacturer: Ethics Health Care Pvt Ltd
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 acphyllin 100mg capsule Uses & Benefits

Bronchial asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis

Off-label uses: Apnea of prematurity, Post-extubation stridor

📋 Drug Information

Generic Name(s)	Acebrophylline
Brand Name	Ab Phylline
Manufacturer	Ethics Health Care Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	RESPIRATORY
Action Class	Theophylline & its derivatives
Route of Administration	Oral
Storage	Store at room temperature (20-25°C), protect from light and moisture
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration

DistributionWidely distributed in body tissues

Protein BindingApproximately 50-60%

MetabolismHepatic metabolism via CYP450 enzymes

Half-Life8-12 hours

ExcretionRenal excretion (primarily as metabolites)

BioavailabilityApproximately 70-80%

Onset of Action30-60 minutes

Peak Plasma Time2-4 hours

Duration of Action8-12 hours

How It Works

Inhibits phosphodiesterase and exhibits anti-inflammatory and bronchodilator effects

Mechanism Steps

1Inhibition of phosphodiesterase (PDE) enzymes, leading to increased intracellular cAMP and cGMP levels

2Relaxation of bronchial smooth muscle (bronchodilation)

3Anti-inflammatory effects via reduction of cytokine release and eosinophil activity

💡 How to Take acphyllin 100mg capsule

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of acphyllin 100mg capsule

✅ Common Side Effects

Nausea
Vomiting
Headache
Insomnia
Tremor
Palpitations

🚨 Serious Side Effects

Seizures
Arrhythmias
Severe hypotension
Allergic reactions

⚠️ Rare Side Effects

Rhabdomyolysis
Hyperglycemia
Hypokalemia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Theophylline	Moderate	Increased risk of theophylline toxicity
Warfarin	Moderate	Increased anticoagulant effect
Cimetidine	Moderate	Increased acebrophylline levels

🚨 Major Interactions

Theophylline
Cimetidine
Ciprofloxacin
Erythromycin
Fluvoxamine

⚡ Moderate Interactions

Lithium
Beta-blockers
Phenytoin
Rifampin

ℹ️ Minor Interactions

Caffeine
Alcohol
Smoking

🍽️ Food Interactions

High-fat meals may delay absorption; avoid excessive caffeine intake

🍷 Alcohol Interaction

May increase risk of gastrointestinal irritation

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category C

🚫 Contraindications

Hypersensitivity to acebrophylline or any component, acute myocardial infarction, hyperthyroidism, peptic ulcer

📊 Monitoring Parameters

Lung function tests, serum drug levels (if co-administered with theophylline), heart rate, blood pressure

🤱 Lactation Safety

Use with caution; excreted in breast milk

💊 Overdose Management

Symptomatic and supportive treatment; induce vomiting or gastric lavage; monitor cardiac function

⏰ Missed Dose

Take as soon as remembered unless near next dose; skip missed dose if close to next dose; do not double dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for acphyllin 100mg capsule

View All

Alternative brands with exact same active ingredient (Acebrophylline (100mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.