brocus 100 capsule - Acebrophylline (100mg) medicine

Abrolin Capsule (Acebrophylline 100 mg): Complete Medicine Guide

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🏭 Zencus Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
🤰 Pregnancy Category Not established from the available information. Consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
  • Irregular or rapid heartbeat
  • Severe skin rash with blisters or peeling
  • Yellowing of eyes or skin, dark urine
  • Difficulty in urination
  • Seizures or severe dizziness

If experiencing severe symptoms, call emergency services immediately.

What is brocus 100 capsule used for?

This medicine is an oral bronchodilator and mucolytic containing Acebrophylline 100 mg. It is used to treat asthma and COPD by relaxing airway muscles and thinning mucus. It is not for sudden severe attacks.

  • Generic Name: Acebrophylline (100mg)
  • Manufacturer: Zencus Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 brocus 100 capsule के बारे में (Hindi Summary)

उपयोग: यह दवा एसब्रोफिलिन 100 मिलीग्राम कैप्सूल है, जिसका उपयोग अस्थमा और सीओपीडी जैसी श्वसन संबंधी समस्याओं के इलाज के लिए किया जाता है। यह श्वास नलियों की मांसपेशियों को आराम देकर सांस लेना आसान बनाती है और बलगम को पतला करके बाहर निकालने में मदद करती है। यह दवा अचानक होने वाले गंभीर अस्थमा हमले के लिए नहीं है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, पेट में असहजता, सिरदर्द और चक्कर आना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। कभी-कभी दिल की धड़कन तेज होना, त्वचा पर दाने, या पेशाब करने में कठिनाई जैसे गंभीर दुष्प्रभाव भी हो सकते हैं। यदि कोई गंभीर या लगातार दुष्प्रभाव हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। कैप्सूल को चबाएं या तोड़ें नहीं, पूरा निगल लें। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है, लेकिन पेट की परेशानी से बचने के लिए भोजन के साथ लेना बेहतर है। इस दवा के सेवन के दौरान शराब न पिएं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएं। अपने डॉक्टर को हृदय, यकृत, गुर्दे की बीमारी या मधुमेह के बारे में बताएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 brocus 100 capsule Uses & Benefits

[{"condition":"Bronchial asthma","description":"Helps relieve bronchospasm and reduces mucus viscosity, improving breathing in patients with asthma.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Used as a bronchodilator and mucolytic to ease symptoms of chronic bronchitis and emphysema.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Helps in thinning mucus and improving cough clearance in chronic bronchitis.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Sinusitis","description":"Sometimes used off-label to help thin mucus in sinusitis, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Bronchial asthma

Also treats: COPD, Chronic bronchitis

📋 Drug Information

Generic Name(s)Acebrophylline (100mg)
Brand Namebrocus 100 capsule
ManufacturerZencus Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassTheophylline & its derivatives
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent levels.
2
Do not use this medicine for sudden severe breathing difficulty; use your rescue inhaler instead.
3
Inform your doctor if you have heart, liver, or kidney disease before starting this medicine.
4
Avoid alcohol and caffeine while taking this medicine to reduce side effects.
5
Do not stop this medicine abruptly without consulting your doctor.
6
Report any palpitations, skin rash, or difficulty in urination immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Wheezing
This medicine is commonly prescribed for this.
Likely Use
Chest tightness
This medicine helps relax airway muscles.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAcebrophylline is rapidly absorbed from the gastrointestinal tract after oral administration. The exact bioavailability is not established from the available information.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismAcebrophylline is metabolized in the liver, primarily by conjugation and oxidation pathways. The exact enzymes involved are not established from the available information.
Half-LifeNot established from the available information.
ExcretionAcebrophylline and its metabolites are primarily excreted through the urine and feces. The exact proportions are not established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionThe onset of action is typically within 30 to 60 minutes after oral administration, but this may vary.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe duration of action is approximately 8 to 12 hours, but this may vary.

How It Works

Acebrophylline is a derivative of ambroxol and theophylline. It works by inhibiting phosphodiesterase enzymes, which increases cyclic AMP levels in bronchial smooth muscle cells, leading to relaxation of the airways. Additionally, it reduces the viscosity of mucus by altering the composition of bronchial secretions, making it easier to expel. It also has anti-inflammatory properties that help reduce airway inflammation.

Mechanism Steps

1
Phosphodiesterase inhibition: Acebrophylline inhibits phosphodiesterase enzymes in bronchial smooth muscle, leading to increased cyclic AMP levels.
2
Bronchial smooth muscle relaxation: Elevated cyclic AMP causes relaxation of bronchial smooth muscle, resulting in bronchodilation and easier breathing.
3
Mucus viscosity reduction: The medicine alters the composition of mucus, reducing its viscosity and making it easier to cough out.
4
Anti-inflammatory action: It reduces the release of inflammatory mediators, helping to decrease airway inflammation and swelling.

💡 How to Take brocus 100 capsule

Strength: Acebrophylline 100 mg immediate-release capsule

1Swallow the capsule whole with a glass of water.
2Do not crush, chew, or open the capsule.
3Take with or without food, but with food if it upsets your stomach.
4Take at the same time each day to maintain consistent levels.
5If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 100 mg taken orally once or twice daily, or as directed by your doctor. The dose may be adjusted based on your condition and response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be necessary based on renal and hepatic function. Consult your doctor.
Renal ImpairmentDose adjustment may be required in patients with kidney disease. Consult your doctor.
Hepatic ImpairmentDose adjustment may be required in patients with liver disease. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 200 mg, but this may vary. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase stimulant effects.
High-fat meals
Avoid taking with
May delay absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of brocus 100 capsule

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated and avoid heavy meals. Consult doctor if severe.
Stomach discomfort (Common (5-10%))
Take with food or milk. If it continues, consult your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if it persists.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel normal.

🚨 Serious Side Effects

Palpitations (Uncommon (1-2%))
Seek immediate medical attention if you experience rapid or irregular heartbeat.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you notice swelling of face, lips, or throat, or difficulty breathing.
Skin rash (Uncommon (1-2%))
Stop the medicine and consult your doctor immediately.
Difficulty in urination (Rare (<0.1%))
Consult your doctor if you have trouble passing urine.

⚠️ Rare Side Effects

Severe skin reactions (Stevens-Johnson syndrome)
Seek immediate medical attention if you develop a severe rash with blisters or peeling skin.
Liver enzyme elevation
Report yellowing of eyes or skin, dark urine, or abdominal pain to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Theophylline Major
Ciprofloxacin Major
Beta-blockers Moderate
Diuretics Moderate
Antacids Minor

🚨 Major Interactions

  • Theophylline
  • Ciprofloxacin

⚡ Moderate Interactions

  • Beta-blockers (e.g., propranolol)
  • Diuretics (e.g., furosemide)

🍷 Alcohol Interaction

Alcohol may increase dizziness, drowsiness, and the risk of stomach upset while taking this medicine. It is advisable to avoid alcohol during treatment.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to acebrophylline or any component of the formulation","Severe liver disease","Severe kidney disease","Uncontrolled cardiac arrhythmias","Acute severe asthma attack (not for emergency use)"]

⚠️ Warnings & Precautions

["Do not use for acute asthma attacks; seek emergency care.","Use with caution in patients with heart disease, hypertension, or hyperthyroidism.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol consumption.","Consult your doctor before taking any other medication, including over-the-counter products.","Do not exceed the prescribed dose."]

🤱 Lactation Safety

It is not known whether acebrophylline passes into breast milk. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause nausea, vomiting, palpitations, seizures, and difficulty breathing. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or open the capsule; swallow it whole with a glass of water. It can be taken with or without food, but taking it with food may reduce stomach upset. Avoid drinking alcohol while taking this medicine as it may increase dizziness and drowsiness. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have heart disease, liver disease, kidney disease, or diabetes. Do not stop taking this medicine suddenly without consulting your doctor. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and palpitations. Dose adjustment may be needed based on kidney and liver function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with certain anesthetic agents.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may cause dry mouth, which can affect dental health. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Use a humidifier to keep the air moist.
😴
Practice deep breathing exercises.
💧
Stay hydrated to help thin mucus.
🧘
Get adequate rest and avoid strenuous activity during flare-ups.

🏋️ Exercise Considerations

Avoid strenuous exercise during acute flare-ups. Consult your doctor before starting any exercise program. Gentle activities like walking may be beneficial when symptoms are controlled.

🥗 Diet Recommendations

Include plenty of fluids
Eat fruits and vegetables rich in antioxidants
Avoid processed foods and excessive salt
Limit caffeine intake

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not affect your ability to work if you are not experiencing side effects.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Your doctor will decide if and when to stop the medicine.

📅 Long-Term Use Effects

Long-term use of this medicine may require periodic monitoring of liver and kidney function. It is generally well-tolerated, but prolonged use should be under medical supervision. Do not stop suddenly without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Inhaled corticosteroids

First-line controller therapy for asthma.

Evidence: Well-established
Pulmonary rehabilitation

Exercise and education program for COPD.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Patients with chronic respiratory diseases should receive annual influenza and pneumococcal vaccinations as per guidelines. This medicine does not interact with vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture and direct sunlight. If traveling across time zones, adjust your dosing schedule in consultation with your doctor. Keep enough supply for the entire trip and carry it in your hand luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with chronic bronchitis
He was prescribed this medicine for his persistent cough and breathlessness. After taking it regularly for two weeks, he noticed that his cough became more productive and breathing felt easier. He experienced mild nausea initially, which went away when he started taking it with food.
💡 Lesson: Taking this medicine with food can reduce stomach upset and improve tolerability.
👤 A 40-year-old woman with asthma
She was given this medicine as an add-on to her inhaler. She initially thought it would replace her inhaler, but her doctor explained it is not for acute attacks. She continued her inhaler for sudden symptoms and used this medicine regularly. Her asthma control improved significantly.
💡 Lesson: This medicine is a controller medication and should not replace a rescue inhaler for acute attacks.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after taking a dose, but full effects may take a few days of regular use.

Q: Can I take it with other asthma medicines?

A: Yes, but you must inform your doctor about all other medicines you are taking to avoid interactions.

Q: Is it safe during pregnancy?

A: The safety of this medicine during pregnancy is not well established. Consult your doctor before use.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for brocus 100 capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used as a rescue inhaler during an asthma attack.
    Fact: This medicine is not for immediate relief of acute asthma attacks. It is a controller medication and should not replace a rescue inhaler.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for people with severe liver or kidney disease, or certain heart conditions. Always consult a doctor.

🔄 Alternative Options

Generic Alternatives

  • Acebrophylline 100 mg capsule

Brand Alternatives

  • Abrolin
  • Acebrophylline
  • Acebrophylline 100 mg

📊 Comparison with Similar Medicines

[{"medicine":"Acebrophylline","class":"Bronchodilator/mucolytic","main_use":"Asthma, COPD","route":"Oral"},{"medicine":"Ambroxol","class":"Mucolytic","main_use":"Mucus clearance","route":"Oral"},{"medicine":"Theophylline","class":"Bronchodilator","main_use":"Asthma, COPD","route":"Oral"}]

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