lazine m dry syrup - Levocetirizine (2.5mg/5ml) + Montelukast (4mg/5ml) medicine

Montair LC Kid Syrup: Complete Guide for Parents

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🏭 Hetero Drugs Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for allergic rhinitis and asthma in children.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or wheezing that does not improve with rescue inhaler
  • Swelling of face, lips, or throat
  • Severe skin rash or hives
  • Yellowing of eyes or skin
  • Unusual mood changes, agitation, or hallucinations
  • Severe abdominal pain
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is lazine m dry syrup used for?

This medicine is a combination syrup used in children to treat allergic rhinitis and mild asthma. It contains levocetirizine (antihistamine) and montelukast (leukotriene blocker). It relieves sneezing, runny nose, and wheezing. Give as prescribed, usually once daily.

  • Generic Name: Levocetirizine (2.5mg/5ml) + Montelukast (4mg/5ml)
  • Manufacturer: Hetero Drugs Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 lazine m dry syrup के बारे में (Hindi Summary)

उपयोग: यह दवा बच्चों में एलर्जी राइनाइटिस (नाक बहना, छींक आना, आंखों में खुजली) और हल्के दमा (अस्थमा) के इलाज के लिए दी जाती है। यह सूजन और एलर्जी को कम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, सिरदर्द, पेट दर्द, मुंह सूखना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन मूड में बदलाव, बेचैनी, या एलर्जी प्रतिक्रिया हो सकती है। तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही दें। खुराक न बढ़ाएं। दवा से नींद आ सकती है, इसलिए बच्चे को साइकिल चलाने या खेलने से रोकें। ठंडी और सूखी जगह पर रखें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 lazine m dry syrup Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy eyes, and nasal congestion in children with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Mild persistent asthma","description":"Helps control asthma symptoms and reduces the frequency of exacerbations in children.","evidence":"Well-established"},{"condition":"Exercise-induced bronchoconstriction","description":"Prevents narrowing of airways triggered by physical activity.","evidence":"Well-established"},{"condition":"Chronic urticaria","description":"Provides relief from itching and hives in allergic skin conditions.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Sleep-related breathing disorders","description":"Sometimes used off-label to improve sleep quality in children with mild obstructive sleep apnea, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Mild persistent asthma, Exercise-induced bronchoconstriction, Chronic urticaria

📋 Drug Information

Generic Name(s)Levocetirizine (2.5mg/5ml) + Montelukast (4mg/5ml)
Brand Namelazine m dry syrup
ManufacturerHetero Drugs Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Give this medicine at the same time each day for best results.
2
Use the measuring cup provided; household spoons are not accurate.
3
If your child has asthma, always keep a rescue inhaler available.
4
Monitor for mood changes or sleep disturbances and report to your doctor.
5
Do not use this medicine for acute asthma attacks; it is for prevention.
6
Consult your doctor before giving any other cold or allergy medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Sneezing and runny nose
This medicine is commonly prescribed for allergic rhinitis.
Likely Use
Wheezing and shortness of breath
Used for mild asthma and exercise-induced bronchoconstriction.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Productive cough
Not indicated for infectious cough.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevocetirizine is rapidly absorbed after oral administration, with peak plasma concentrations reached in about 1 hour. Montelukast is also rapidly absorbed, with peak levels in 2 to 4 hours. Food does not significantly affect the absorption of either component.
DistributionLevocetirizine distributes into body tissues, and its plasma protein binding is approximately 90%. Montelukast is highly protein-bound (>99%) and has a small volume of distribution.
Protein BindingLevocetirizine: about 90%; Montelukast: greater than 99%.
MetabolismLevocetirizine undergoes minimal metabolism, with about 14% converted to inactive metabolites. Montelukast is extensively metabolized in the liver by CYP2C8 and CYP3A4 enzymes.
Half-LifeLevocetirizine: 6 to 8 hours in children; Montelukast: 2.7 to 5.5 hours.
ExcretionLevocetirizine is primarily excreted unchanged in urine. Montelukast is excreted mainly in bile and feces.
BioavailabilityLevocetirizine: approximately 100%; Montelukast: approximately 64% for the 10 mg tablet, but for the 4 mg oral granules it is about 73%.
Onset of ActionLevocetirizine begins to relieve allergy symptoms within 1 hour. Montelukast may take a few days to show full effect for asthma control.
Peak Plasma TimeLevocetirizine: 1 hour; Montelukast: 2 to 4 hours.
Duration of ActionLevocetirizine: 24 hours; Montelukast: 24 hours.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Levocetirizine selectively blocks histamine H1 receptors, reducing allergic symptoms such as sneezing, itching, and vasodilation. Montelukast selectively blocks cysteinyl leukotriene receptors (CysLT1), preventing leukotriene-mediated bronchoconstriction, mucus secretion, and airway edema. Together, they address both histamine and leukotriene pathways involved in allergic inflammation.

Mechanism Steps

1
Histamine H1 receptor blockade: Levocetirizine binds to H1 receptors on blood vessels and nerve endings, preventing histamine from triggering allergy symptoms.
2
Leukotriene receptor antagonism: Montelukast blocks CysLT1 receptors on airway smooth muscle and inflammatory cells, reducing bronchoconstriction and inflammation.
3
Reduced allergic inflammation: The combined action decreases the release of inflammatory mediators and reduces mucus secretion and airway edema.
4
Symptom relief: Patients experience less sneezing, runny nose, itching, and improved breathing during allergic episodes and exercise.

💡 How to Take lazine m dry syrup

Strength: Each 5 ml contains Levocetirizine 2.5 mg and Montelukast 4 mg.

1Shake the bottle well before each use.
2Use the measuring cup or oral syringe provided to measure the exact dose.
3Give the medicine directly into the mouth or mix with a small amount of soft food like yogurt or applesauce.
4If mixed with food, ensure the entire mixture is consumed immediately.
5Give with or without food, but consistent timing helps.
6Wash the measuring cup after each use.

Dosage Information

Adult DosageThis pediatric syrup is not typically prescribed for adults. Adults usually take higher-strength tablet formulations. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosageFor children 6 months to 5 years: usual dose is 2.5 ml once daily or as prescribed. For children 6 to 11 years: 5 ml once daily. Dose may be adjusted by the doctor based on weight and condition. Always use the measuring cup provided.
Elderly DosageNot applicable for this pediatric formulation. Elderly patients should use adult formulations with dose adjustment based on renal function.
Renal ImpairmentLevocetirizine dose should be reduced in renal impairment. Montelukast does not require adjustment. Consult a doctor for individualized dosing.
Hepatic ImpairmentNo dose adjustment is needed for mild to moderate hepatic impairment. In severe hepatic impairment, use with caution and consult a doctor.
Maximum Daily DoseLevocetirizine: 5 mg/day for children 6-11 years; Montelukast: 5 mg/day for children 6-14 years. Do not exceed prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Can be taken with or without food
Food does not affect absorption.
Grapefruit
Avoid large amounts
May increase montelukast levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Give the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of lazine m dry syrup

✅ Common Side Effects

Drowsiness (Common (5-10%))
Usually resolves on its own. Avoid activities requiring alertness until you know how it affects your child.
Headache (Common (5-10%))
May be relieved with rest or a mild pain reliever if approved by the doctor.
Abdominal pain (Common (2-5%))
Give with food to reduce stomach upset. Consult doctor if persistent.
Dry mouth (Common (2-5%))
Encourage fluids. Sugar-free lozenges may help.
Fatigue (Common (2-5%))
Ensure adequate rest. Consult doctor if it interferes with daily activities.

🚨 Serious Side Effects

Mood changes or agitation (Rare (<0.1%))
Contact doctor immediately if your child shows unusual aggression, anxiety, or depression.
Sleep disturbances (Rare (<0.1%))
Report persistent nightmares or insomnia to the doctor.
Allergic reactions (Rare (<0.1%))
Seek emergency care if you notice rash, swelling, or difficulty breathing.
Liver problems (Very rare (<0.01%))
Watch for yellowing of eyes or skin, dark urine, or abdominal pain. Seek medical attention.

⚠️ Rare Side Effects

Hallucinations
Seek immediate medical help.
Suicidal thoughts
Contact doctor or emergency services immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
CNS depressants Major
Rifampin Major
Alcohol Moderate
Other antihistamines Moderate
Grapefruit juice Minor

🚨 Major Interactions

  • CNS depressants (e.g., benzodiazepines, opioids)
  • Strong CYP3A4 inducers (e.g., rifampin, carbamazepine)

⚡ Moderate Interactions

  • Alcohol
  • Other antihistamines

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness caused by levocetirizine. It is best to avoid alcohol while taking this medicine, especially in children and adolescents.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to levocetirizine, montelukast, or any component","Severe renal impairment (for levocetirizine component)","Children under 6 months for levocetirizine; under 6 months for montelukast (consult doctor)"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until effects are known.","Not for acute asthma attacks; always have a rescue inhaler available.","Neuropsychiatric events have been reported with montelukast; monitor for mood changes.","Use with caution in patients with liver or kidney disease.","Do not exceed recommended dose."]

🤱 Lactation Safety

Not established from the available information. Consult a doctor before use during breastfeeding.

💊 Overdose Management

Seek emergency medical attention. Symptoms of overdose may include extreme drowsiness, agitation, or abdominal pain. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Give this medicine exactly as prescribed by your child's doctor. Do not increase or decrease the dose without consulting the doctor. Avoid giving other antihistamines or cold medicines without checking for interactions. This medicine may cause drowsiness; supervise activities like cycling or climbing. Store at room temperature away from moisture and heat. Keep out of reach of children. If your child has liver or kidney problems, inform the doctor before use. Do not use for acute asthma attacks; always keep a rescue inhaler available.

👴 Special Considerations for Elderly

💡 For Patients Above 65

This pediatric formulation is not intended for elderly patients. Elderly patients should use adult formulations with appropriate dose adjustments.

🤰 Pregnancy Planning (TTC)

Not applicable for pediatric formulation. Consult a doctor if you are pregnant or planning pregnancy.

🏥 Post-Surgery Considerations

Consult your doctor before giving this medicine after surgery, as it may interact with anesthetics or other medications.

🦷 Dental Procedures

Inform your dentist if your child is taking this medicine, as it may cause dry mouth and affect oral health.

💚 Lifestyle Tips for Better Results

🏃
Keep your child away from known allergens like dust, pollen, and pet dander.
🥗
Use air purifiers at home to reduce airborne allergens.
😴
Encourage regular handwashing to prevent infections.
💧
Ensure your child gets plenty of fluids.
🧘
Maintain a clean, dust-free sleeping environment.

🏋️ Exercise Considerations

If your child has exercise-induced asthma, this medicine may help prevent symptoms. However, always carry a rescue inhaler during physical activities. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include fruits and vegetables rich in antioxidants.
Avoid processed foods and artificial additives.
Ensure adequate hydration.
Limit intake of cold drinks and ice cream if they trigger symptoms.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness in some children, affecting school performance and daily activities. Monitor your child's alertness and adjust activities accordingly. It is usually given in the evening to minimize daytime sedation.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If your child experiences serious side effects like mood changes or allergic reactions, seek immediate medical advice. The doctor will decide if and when to discontinue.

📅 Long-Term Use Effects

Long-term use of montelukast has been associated with neuropsychiatric events in some children. Regular monitoring of mood and behavior is advised. Levocetirizine is generally safe for long-term use but may cause tolerance. Periodic review with your doctor is recommended.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Reducing exposure to allergens can decrease the need for medication.

Evidence: Well-established
Immunotherapy

Allergy shots may provide long-term relief for allergic rhinitis.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interfere with routine vaccinations. However, consult your doctor before any vaccination if your child is unwell.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label. Keep it in your hand luggage to avoid temperature extremes. If traveling across time zones, maintain the same dosing schedule as prescribed. Carry a copy of the prescription for customs. Store away from direct sunlight and heat.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 4-year-old boy with frequent sneezing and runny nose during pollen season.
His mother started giving this medicine as prescribed by the pediatrician. Within a week, his sneezing and nasal congestion reduced significantly. She noted that giving it in the evening helped him sleep better without daytime drowsiness.
💡 Lesson: Consistent evening dosing can improve symptoms and minimize daytime sedation.
👤 A 7-year-old girl with mild asthma and exercise-induced wheezing.
She was prescribed this syrup along with an inhaler. After a month, she could play sports with fewer breathing difficulties. Her parents were advised to watch for mood changes, which they did not observe.
💡 Lesson: Combination therapy can improve asthma control, but monitoring for neuropsychiatric effects is important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Levocetirizine starts working within 1 hour, while montelukast may take a few days for full effect.

Q: Can I give this medicine with food?

A: Yes, it can be given with or without food. Giving with food may reduce stomach upset.

Q: What if my child vomits after taking the dose?

A: If vomiting occurs within 30 minutes, consult your doctor; do not repeat the dose without advice.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I give this medicine to my child daily?
  • Will it cause drowsiness?
  • Does it affect growth?
  • Can it be given with other medicines?
  • What if I miss a dose?
  • Is it safe for long-term use?

🔄 Substitutes for lazine m dry syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any cough and cold.
    Fact: It is specifically for allergic conditions and asthma, not for common cold or infections.
  • Myth: It is safe to give extra doses if symptoms are severe.
    Fact: Never exceed the prescribed dose; it can cause serious side effects.

🔄 Alternative Options

Generic Alternatives

  • Levocetirizine + Montelukast oral syrup (generic)

Brand Alternatives

  • Montair LC Kid Syrup
  • Levocet-M Kid Syrup
  • Montelukast + Levocetirizine Syrup (various brands)

📊 Comparison with Similar Medicines

[{"medicine":"Montair LC Kid Syrup","composition":"Levocetirizine 2.5mg/5ml + Montelukast 4mg/5ml","use":"Allergic rhinitis, asthma","form":"Syrup"},{"medicine":"Montelukast alone","composition":"Montelukast 4mg/5ml","use":"Asthma, allergic rhinitis","form":"Syrup"},{"medicine":"Levocetirizine alone","composition":"Levocetirizine 2.5mg/5ml","use":"Allergic rhinitis, urticaria","form":"Syrup"}]

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