What is acolate kid syrup mango used for?

This medicine is a combination syrup containing chlorpheniramine maleate (an antihistamine) and paracetamol (a pain reliever and fever reducer). It is used in children to treat symptoms of cold and allergies, such as runny nose, sneezing, and fever. It should be used only as directed by a doctor.

Generic Name: Chlorpheniramine Maleate + Paracetamol
Manufacturer: Gujarat Terce Laboratories Ltd
Form: Allopathy
Pregnancy Category: Consult doctor
Prescription Required: Yes

🇮🇳 acolate kid syrup mango के बारे में (Hindi Summary)

उपयोग: यह दवा बच्चों में सर्दी-जुकाम और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना, आंखों में खुजली और हल्के बुखार को कम करने के लिए दी जाती है। इसमें क्लोरफेनिरामाइन मेलिएट और पैरासिटामोल दो सक्रिय तत्व होते हैं। क्लोरफेनिरामाइन एलर्जी को कम करता है और पैरासिटामोल बुखार और दर्द को कम करता है। यह दवा आमतौर पर 2 साल से बड़े बच्चों के लिए होती है, लेकिन डॉक्टर की सलाह के बिना न दें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना, जी मिचलाना और धुंधली दृष्टि शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। कभी-कभी गंभीर एलर्जी प्रतिक्रिया हो सकती है जैसे चकत्ते, चेहरे या गले में सूजन, सांस लेने में कठिनाई। अगर ऐसा हो तो तुरंत डॉक्टर से मिलें। पैरासिटामोल की अधिक मात्रा से लिवर को नुकसान हो सकता है।

सुरक्षा सलाह: इस दवा को हमेशा मापने वाले कप या सिरिंज से ही दें। दवा की मात्रा या बार-बार देने की संख्या न बढ़ाएं। बिना डॉक्टर की सलाह के अन्य पैरासिटामोल या एंटीहिस्टामिन वाली दवाएं न दें। इस दवा से नींद आ सकती है, इसलिए बच्चों को साइकिल चलाने या खेलने से रोकें। दवा को ठंडी और सूखी जगह पर रखें, धूप से बचाएं। अगर 5 दिनों से ज्यादा लक्षण बने रहें तो डॉक्टर से मिलें।

💊 acolate kid syrup mango Uses & Benefits

[{"condition":"Common cold","description":"Relieves runny nose, sneezing, and mild fever associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Reduces sneezing, rhinorrhea, and itching of the nose and throat due to allergies.","evidence":"Well-established"},{"condition":"Urticaria","description":"Helps relieve itching and hives associated with allergic skin reactions.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces mild to moderate fever from various causes.","evidence":"Well-established"},{"condition":"Mild pain","description":"Provides relief from minor aches and pains, such as headache or body ache.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Common cold and allergic rhinitis

Also treats: Urticaria, Fever, Mild pain

📋 Drug Information

Generic Name(s)	Chlorpheniramine Maleate + Paracetamol
Brand Name	Alex P Syrup
Manufacturer	Gujarat Terce Laboratories Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	RESPIRATORY
Action Class	Antihistamine + Analgesic/Antipyretic
Route of Administration	Oral
Storage	Store at room temperature (15-30°C) in a cool, dry place, away from direct sunlight. Do not refrigerate. Keep the bottle tightly closed.
Shelf Life	24 months from the date of manufacture.
WHO Guideline	Not established from the available information.
ICMR Guideline	Not established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1

Always use the measuring device provided to ensure accurate dosing.

2

Do not exceed the recommended dose or frequency.

3

Avoid using other paracetamol-containing products simultaneously.

4

Monitor for excessive drowsiness and avoid activities requiring alertness.

5

Consult a doctor if symptoms persist beyond 5 days or worsen.

6

Keep the medicine out of reach of children.

7

Do not use in children under 2 years without medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅

Runny nose

This medicine is commonly prescribed for this.

Likely Use

✅

Sneezing

This medicine is commonly prescribed for this.

Likely Use

✅

Fever

This medicine contains paracetamol which reduces fever.

Likely Use

✅

Itchy eyes

This medicine contains an antihistamine which relieves itching.

Likely Use

❌

Cough

This medicine is not a cough suppressant.

Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine maleate is well absorbed from the gastrointestinal tract after oral administration. Paracetamol is also rapidly and almost completely absorbed from the gastrointestinal tract. The syrup formulation allows for rapid absorption, especially in children.

DistributionChlorpheniramine maleate is widely distributed throughout the body, including the central nervous system. Paracetamol distributes rapidly into most body tissues, with a volume of distribution of about 0.9 L/kg.

Protein BindingChlorpheniramine maleate is approximately 70% bound to plasma proteins. Paracetamol is only minimally bound to plasma proteins (about 10-25%).

MetabolismChlorpheniramine maleate is metabolized in the liver, primarily by CYP2D6 and CYP3A4 enzymes. Paracetamol is metabolized in the liver via glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate, N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified by glutathione.

Half-LifeThe elimination half-life of chlorpheniramine maleate is approximately 12-15 hours in adults and may be longer in children. The elimination half-life of paracetamol is about 2-3 hours in children.

ExcretionChlorpheniramine maleate and its metabolites are excreted primarily in the urine. Paracetamol metabolites are excreted in the urine, with about 90% of the dose excreted within 24 hours.

BioavailabilityChlorpheniramine maleate has a bioavailability of about 25-50% due to first-pass metabolism. Paracetamol has a high bioavailability of about 80-100% after oral administration.

Onset of ActionChlorpheniramine maleate begins to relieve allergic symptoms within 30-60 minutes after oral administration. Paracetamol starts to reduce fever and pain within 30-60 minutes.

Peak Plasma TimeChlorpheniramine maleate reaches peak plasma concentrations in about 2-3 hours. Paracetamol reaches peak plasma concentrations in about 30-60 minutes.

Duration of ActionChlorpheniramine maleate's effects last for about 4-6 hours, while paracetamol's effects last for about 4-6 hours. The syrup may be dosed every 4-6 hours as needed.

How It Works

This medicine combines an antihistamine and an analgesic-antipyretic. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, thereby preventing histamine-mediated allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation. Paracetamol (acetaminophen) acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which leads to reduction of fever and pain perception. The exact mechanism of paracetamol's analgesic and antipyretic effects is not fully understood but is thought to involve inhibition of cyclooxygenase enzymes in the brain and spinal cord.

Mechanism Steps

1

Histamine H1 receptor blockade: Chlorpheniramine maleate binds to histamine H1 receptors on effector cells, preventing histamine from triggering allergic responses such as sneezing, runny nose, and itching.

2

Central prostaglandin inhibition: Paracetamol inhibits prostaglandin synthesis in the central nervous system, which reduces fever and elevates pain threshold.

3

Anticholinergic effects: Chlorpheniramine also exhibits anticholinergic properties, which contribute to drying of respiratory secretions, reducing runny nose.

4

Sedation: Chlorpheniramine crosses the blood-brain barrier and causes drowsiness by blocking histamine in the brain, where histamine promotes wakefulness.

💡 How to Take acolate kid syrup mango

Strength: Each 5 ml of syrup contains chlorpheniramine maleate 1 mg and paracetamol 125 mg.

1Shake the bottle well before use.

2Use the measuring cup or syringe provided to measure the exact dose.

3Administer orally, with or without food.

4If giving with food, give after a meal to reduce stomach upset.

5Do not exceed the recommended dose or frequency.

6Wash the measuring device after each use.

Dosage Information

Adult Dosage	This medicine is intended for pediatric use. For adults, dosing should be individualized by a qualified clinician based on the indication, age, weight, and renal and hepatic function. Typically, the adult dose of chlorpheniramine maleate is 4 mg every 4-6 hours, and paracetamol is 500-1000 mg every 4-6 hours as needed, not to exceed 4000 mg per day. However, this specific syrup formulation is not intended for adults unless prescribed.
Pediatric Dosage	Pediatric dosing is not established from available information. Consult a pediatrician. The dose depends on the child's age and weight. Generally, for children 2-6 years, 2.5 ml every 4-6 hours may be given, but this must be confirmed by a doctor. Do not use in children under 2 years without medical advice.
Elderly Dosage	This medicine is intended for pediatric use. For elderly patients, dosing should be individualized by a qualified clinician. Elderly patients are more sensitive to the anticholinergic and sedative effects of chlorpheniramine, and paracetamol dose should be adjusted in hepatic or renal impairment.
Renal Impairment	Dose adjustment may be required in renal impairment. Consult a doctor for appropriate dosing.
Hepatic Impairment	Dose adjustment may be required in hepatic impairment. Paracetamol should be used with caution and at reduced doses in patients with liver disease. Consult a doctor.
Maximum Daily Dose	For children, the maximum daily dose of paracetamol should not exceed 60 mg/kg/day, and chlorpheniramine should not exceed 0.35 mg/kg/day. Do not exceed 4 doses in 24 hours. Always follow the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food

Take with meals

Reduces stomach upset.

Grapefruit

Avoid

May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed

→ Give the missed dose as soon as you remember.

💡 Continue with the regular schedule.

📌 More than half the dosing interval has passed

→ Skip the missed dose.

💡 Do not double dose to catch up.

⚠️ Side Effects of acolate kid syrup mango

✅ Common Side Effects

Drowsiness (Common (up to 10%))

Usually resolves with continued use. Avoid activities requiring alertness. Consult doctor if persistent.

Dry mouth (Common (5-10%))

Encourage fluids. Usually temporary.

Dizziness (Common (5-10%))

Have the child sit or lie down until it passes. Consult doctor if severe.

Nausea (Common (5-10%))

Give with food or milk to reduce stomach upset.

Blurred vision (Uncommon (1-5%))

Usually temporary. Consult doctor if persistent.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))

Seek immediate medical attention if you notice rash, swelling of face, lips, or throat, difficulty breathing, or fainting.

Liver damage (paracetamol overdose) (Rare (<0.1%))

Seek immediate medical attention if you suspect overdose, even if no symptoms are present. Symptoms may include nausea, vomiting, abdominal pain, and yellowing of skin or eyes.

Blood dyscrasias (Very rare (<0.01%))

Report unusual bleeding, bruising, or persistent sore throat to a doctor.

Seizures (Very rare (<0.01%))

Seek immediate medical attention if seizures occur.

⚠️ Rare Side Effects

Paradoxical excitation (restlessness, irritability)

Consult doctor if child becomes unusually restless or irritable.

Urinary retention

Consult doctor if child has difficulty urinating.

Photosensitivity

Protect from sunlight and consult doctor if rash develops.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug	Severity	Effect
Other paracetamol products	Major
MAOIs	Major
CNS depressants	Major
Warfarin	Moderate
Alcohol	Moderate
Anticholinergics	Moderate
Antacids	Minor
Cholestyramine	Minor

🚨 Major Interactions

Other paracetamol-containing products
Monoamine oxidase inhibitors (MAOIs)
CNS depressants (e.g., benzodiazepines, opioids)

⚡ Moderate Interactions

Warfarin
Alcohol
Anticholinergic drugs (e.g., atropine)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase the risk of liver toxicity from paracetamol and enhance the sedative effects of chlorpheniramine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chlorpheniramine maleate, paracetamol, or any component of the formulation","Neonates and premature infants","Severe liver disease","Severe kidney disease","Narrow-angle glaucoma","Urinary retention","Severe asthma"]

⚠️ Warnings & Precautions

["Do not exceed recommended dose.","Avoid concurrent use with other paracetamol-containing products.","May cause drowsiness; avoid activities requiring alertness.","Use with caution in children with liver or kidney disease.","Use with caution in children with asthma or other chronic respiratory conditions.","Do not use for more than 5 days without consulting a doctor.","Keep out of reach of children."]

🤱 Lactation Safety

Not established from the available information. This medicine is intended for pediatric use. Consult a doctor for use during breastfeeding.

💊 Overdose Management

Overdose of this medicine can cause severe liver damage due to paracetamol and anticholinergic toxicity due to chlorpheniramine. Symptoms of paracetamol overdose may include nausea, vomiting, abdominal pain, and yellowing of skin or eyes, but may be delayed. If overdose is suspected, seek immediate medical attention. Treatment may include administration of N-acetylcysteine as an antidote for paracetamol toxicity, and supportive care for anticholinergic effects. Do not induce vomiting unless instructed by a healthcare professional.

⏰ Missed Dose

If a dose is missed, give it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always use the measuring device provided with this medicine to ensure accurate dosing. Do not exceed the recommended dose or frequency. Avoid using other medications that contain paracetamol or antihistamines without consulting a doctor, as this can lead to overdose or increased side effects. This medicine may cause drowsiness; therefore, children should avoid activities requiring alertness, such as riding a bicycle or playing sports, until you know how it affects them. Keep this medicine out of reach of children. Store in a cool, dry place, away from direct sunlight. Do not use after the expiry date. If symptoms persist for more than 5 days or are accompanied by high fever, rash, or persistent headache, seek medical advice. Do not give this medicine to children under 2 years of age without a doctor's prescription.

👴 Special Considerations for Elderly

💡 For Patients Above 65

This medicine is intended for pediatric use. Elderly patients may be more sensitive to the anticholinergic and sedative effects of chlorpheniramine. If prescribed, use with caution and monitor for confusion, urinary retention, and falls.

🤰 Pregnancy Planning (TTC)

This medicine is not intended for use during pregnancy. Consult a doctor for safe alternatives if you are pregnant or planning pregnancy.

🏥 Post-Surgery Considerations

This medicine may cause drowsiness and should be used with caution after surgery. Consult a doctor before use.

🦷 Dental Procedures

This medicine may cause dry mouth, which can affect dental health. Maintain good oral hygiene and consult a dentist if dry mouth persists.

💚 Lifestyle Tips for Better Results

🏃

Ensure your child gets plenty of rest.

🥗

Keep your child well hydrated with fluids like water, soup, and juice.

😴

Use a humidifier to ease nasal congestion.

💧

Avoid exposing your child to smoke or other irritants.

🧘

Practice good hand hygiene to prevent spread of infections.

🏋️ Exercise Considerations

This medicine may cause drowsiness. Children should avoid activities that require alertness, such as swimming, cycling, or playing sports, until the effects wear off.

🥗 Diet Recommendations

Offer warm fluids like soup and tea to soothe the throat.

Include vitamin C rich foods like oranges and strawberries.

Avoid cold drinks and ice cream which may worsen symptoms.

Provide soft, easy-to-swallow foods if the child has a sore throat.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect a child's ability to concentrate in school or perform physical activities. It is advisable to let the child rest at home until symptoms improve.

🛑 When to Stop This Medicine

Stop this medicine and consult a doctor if symptoms do not improve within 5 days, if they worsen, or if any serious side effects occur. Do not stop abruptly if the doctor has prescribed a specific duration.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of chlorpheniramine may lead to tolerance and increased side effects. Prolonged or excessive use of paracetamol can cause liver damage. Regular monitoring of liver and kidney function may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal drops

Can help relieve nasal congestion in children.

Evidence: Well-established

Steam inhalation

May help loosen mucus and ease breathing.

Evidence: Limited

Honey and warm fluids

Can soothe sore throat and cough in children over 1 year.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if the child has a fever, vaccination may be postponed until the child recovers. Consult a doctor for guidance.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of the prescription in case of customs checks. Store it in a cool, dry place, away from direct sunlight. If traveling across time zones, maintain the dosing schedule as close to the original as possible, but consult a doctor for specific advice. Do not leave the medicine in a hot car or checked luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 4-year-old child with runny nose and mild fever

The child was given this medicine as prescribed by the pediatrician. Within 2 days, the runny nose and fever subsided. The parent ensured the child drank plenty of fluids and rested. The child experienced mild drowsiness but no other side effects.

💡 Lesson: This medicine effectively relieves cold symptoms and fever in children when used as directed. Monitoring for drowsiness is important.

👤 A 6-year-old with allergic rhinitis and itchy eyes

The child was prescribed this medicine during allergy season. Symptoms improved significantly, but the child became slightly sleepy. The doctor advised giving the dose at bedtime to minimize daytime drowsiness.

💡 Lesson: Timing the dose can help manage side effects like drowsiness. Always follow medical advice.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts to relieve symptoms within 30-60 minutes after administration.

Q: How often can I give this syrup?

A: It is typically given every 4-6 hours as needed, but do not exceed 4 doses in 24 hours. Follow your doctor's advice.

Q: What should I do if my child vomits after taking the medicine?

A: If vomiting occurs within 30 minutes of taking the dose, consult a doctor before giving another dose. Do not repeat the dose without medical advice.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

Can I take this medicine long-term?
Will it affect my child's kidney function?
Can my child go to school after taking this medicine?
Does it interact with other cold medicines?
What if I miss a dose?
Can I give this with food?

🔄 Substitutes for acolate kid syrup mango

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

Myth: This medicine can cure the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
Myth: It is safe to give multiple doses if symptoms persist.
Fact: Exceeding the recommended dose can lead to serious side effects, especially liver damage from paracetamol.
Myth: It can be used for any age group.
Fact: It is not recommended for children under 2 years without medical advice.

🔄 Alternative Options

Generic Alternatives

Chlorpheniramine maleate + Paracetamol syrup (generic)

Brand Alternatives

Acolate Kid Syrup Mango

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Chlorpheniramine 1mg/5ml + Paracetamol 125mg/5ml","use":"Cold and allergy symptoms with fever"},{"medicine":"Paracetamol alone","composition":"Paracetamol 125mg/5ml","use":"Fever and pain only"},{"medicine":"Chlorpheniramine alone","composition":"Chlorpheniramine 1mg/5ml","use":"Allergy symptoms only"}]

Acolate Kid Syrup Mango: Complete Guide for Parents

When to Call Your Doctor IMMEDIATELY

What is acolate kid syrup mango used for?

🇮🇳 acolate kid syrup mango के बारे में (Hindi Summary)

💊 acolate kid syrup mango Uses & Benefits

📋 Drug Information

👨‍⚕️ Doctor's Practical Tips

🔍 Is This Medicine Right for Your Symptom?

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take acolate kid syrup mango

Dosage Information

Dosage Timeline

🍽️ Food Timing Guide

⏰ What to Do If You Miss a Dose

⚠️ Side Effects of acolate kid syrup mango

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

🍷 Alcohol Interaction

🔎 Check Your Other Medicines

🛡️ Safety & Warnings

🚫 Contraindications

⚠️ Warnings & Precautions

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

Additional Safety Advice

👴 Special Considerations for Elderly

💡 For Patients Above 65

🤰 Pregnancy Planning (TTC)

🏥 Post-Surgery Considerations

🦷 Dental Procedures

💚 Lifestyle Tips for Better Results

🏋️ Exercise Considerations

🥗 Diet Recommendations

💼 Impact on Daily Work & Life

🛑 When to Stop This Medicine

📅 Long-Term Use Effects

🌿 Non-Medicine Approaches

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

📦 Storage Guide

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✈️ Traveling with This Medicine

💰 Cost Analysis & Savings

👥 Real Patient Stories

💬 Questions Patients Often Ask

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

🔄 Substitutes for acolate kid syrup mango

🛑 Myths vs. Facts

🔄 Alternative Options

Generic Alternatives

Brand Alternatives

📊 Comparison with Similar Medicines

😊 Was this information helpful?

Browse Medicines A-Z

✍️ Write a Review

❓ Ask a Question

⚠️ Report an Issue