acnoa 100 mg/50 mg tablet
What is acnoa 100 mg/50 mg tablet used for?
Accept-XL Tablet (Aceclofenac + Diacerein) is used to treat PAIN ANALGESICS. It contains Aceclofenac (100mg) + Diacerein (50mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Diacerei. Always consult your doctor before use. Take as prescribed.
- Generic Name: Aceclofenac + Diacerein
- Manufacturer: MMC Healthcare Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ acnoa 100 mg/50 mg tablet Uses & Benefits
Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis
Off-label uses: Acute gout, soft tissue injuries
๐ Drug Information
| Generic Name(s) | Aceclofenac + Diacerein |
| Brand Name | Accept-XL Tablet |
| Manufacturer | MMC Healthcare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Anthraquinone derivative |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Diacerein inhibits IL-1ฮฒ and stimulates TGF-ฮฒ, modulating cartilage metabolism
Mechanism Steps
๐ก How to Take acnoa 100 mg/50 mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of acnoa 100 mg/50 mg tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Abdominal pain
- Dyspepsia
- Headache
- Dizziness
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Renal failure
- Hepatotoxicity
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Anaphylaxis
- Pancreatitis
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Lithium | Major | Increased lithium toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| Anticoagulants | Major | Enhanced anticoagulant effect |
| Aspirin | Major | Increased GI ulceration risk |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic effect |
| Corticosteroids | Moderate | Increased GI ulceration risk |
| Cyclosporine | Moderate | Increased nephrotoxicity |
| Antacids | Minor | Reduced absorption of diacerein |
| Cholestyramine | Minor | Reduced absorption of diacerein |
๐จ Major Interactions
- Warfarin
- Lithium
- Methotrexate
- Anticoagulants
- Aspirin
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Corticosteroids
- Cyclosporine
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
๐ฝ๏ธ Food Interactions
May be taken with food to reduce GI upset; avoid high-fat meals as may delay absorption
๐ท Alcohol Interaction
Increased risk of GI bleeding
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components, active peptic ulcer, severe hepatic/renal impairment, pregnancy (third trimester), inflammatory bowel disease
๐ Monitoring Parameters
Liver function tests, renal function, blood pressure, signs of GI bleeding
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; gastric lavage if recent; monitor renal and hepatic function
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Found this to be a helpful product. Good results.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.
Helpful and effective medicine as per my experience. Always consult a doctor.