acnetroy gel - Clindamycin (1% w/w) + Nicotinamide (4% w/w) medicine

Acnetroy Gel - Uses, Price, Side Effects, and More

4.4 (18 reviews)
๐Ÿญ Troikaa Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is acnetroy gel used for?

Acnetroy Gel is a combination medicine used to treat acne vulgaris. It contains Clindamycin (an antibiotic) and Nicotinamide (a form of vitamin B3) that work together to kill acne-causing bacteria and reduce inflammation. Apply a thin layer to affected areas twice daily as directed by your doctor.

  • Generic Name: Clindamycin + Nicotinamide
  • Manufacturer: Troikaa Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š acnetroy gel Uses & Benefits

Acne vulgaris, inflammatory acne.

Off-label uses: Rosacea, perioral dermatitis.

๐Ÿ“‹ Drug Information

Generic Name(s)Clindamycin + Nicotinamide
Brand NameAcnetoin Gel
ManufacturerTroikaa Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntibiotic + Vitamin B3 derivative
Route of AdministrationTopical
StorageStore at room temperature (20-25ยฐC), away from moisture and heat.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionTopical absorption is minimal; systemic absorption is low.
DistributionDistributes locally in skin layers; minimal systemic distribution.
Protein BindingClindamycin: ~94% bound to plasma proteins; Nicotinamide: minimal binding.
MetabolismClindamycin: Hepatic metabolism via CYP3A4; Nicotinamide: Hepatic metabolism to N-methylnicotinamide.
Half-LifeClindamycin: ~2-3 hours; Nicotinamide: ~1-2 hours.
ExcretionClindamycin: Renal and biliary; Nicotinamide: Renal.
BioavailabilityLow systemic bioavailability due to topical application.
Onset of ActionWithin a few days to weeks.
Peak Plasma TimeNot applicable for topical use.
Duration of ActionSustained with regular application.

How It Works

Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; Nicotinamide reduces sebum production and has anti-inflammatory effects.

Mechanism Steps

1Clindamycin binds to 50S ribosomal subunit of bacteria, inhibiting protein synthesis.
2Nicotinamide inhibits sebocyte lipid synthesis and reduces inflammatory cytokine production.
3Combination reduces P. acnes population and inflammation.

๐Ÿ’ก How to Take acnetroy gel

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of acnetroy gel

โœ… Common Side Effects

  • Skin dryness
  • Peeling
  • Erythema
  • Burning sensation

๐Ÿšจ Serious Side Effects

  • Pseudomembranous colitis
  • Severe allergic reactions

โš ๏ธ Rare Side Effects

  • Contact dermatitis
  • Urticaria

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Erythromycin Moderate May reduce efficacy of clindamycin
Neuromuscular blocking agents Major Enhanced neuromuscular blockade
Other topical acne treatments Moderate Increased skin irritation

๐Ÿšจ Major Interactions

  • Neuromuscular blocking agents
  • Erythromycin

โšก Moderate Interactions

  • Other topical antibiotics
  • Retinoids

โ„น๏ธ Minor Interactions

  • None significant

๐Ÿฝ๏ธ Food Interactions

None known.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to clindamycin, nicotinamide, or any component; history of antibiotic-associated colitis.

๐Ÿ“Š Monitoring Parameters

Skin irritation, signs of hypersensitivity, improvement in acne lesions.

๐Ÿคฑ Lactation Safety

Clindamycin is excreted in breast milk; use with caution. Nicotinamide is safe.

๐Ÿ’Š Overdose Management

Topical overdose unlikely; if ingested, symptomatic and supportive care.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

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