Aciz MR Tablet: Comprehensive Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain or persistent heartburn
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output or swelling in legs
- Unusual bruising or bleeding
- Severe skin rash with blisters or peeling
If experiencing severe symptoms, call emergency services immediately.
What is aciz mr tablet used for?
This medicine is a combination of Aceclofenac and Paracetamol used for short-term relief of acute pain and inflammation. It works by reducing prostaglandins that cause pain and swelling. Take it with food to avoid stomach upset and do not exceed the prescribed dose.
- Generic Name: Aceclofenac + Paracetamol
- Manufacturer: Ritz Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 aciz mr tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एसिटाक्लोफेनाक और पैरासिटामोल का संयोजन है, जिसका उपयोग तीव्र दर्द और सूजन के अल्पकालिक उपचार के लिए किया जाता है। यह जोड़ों के दर्द, मांसपेशियों के दर्द, दांत दर्द, पीठ दर्द, मासिक धर्म के दर्द और सर्जरी के बाद के दर्द में राहत देती है। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो। इसका उपयोग डॉक्टर के परामर्श के बिना 7 दिनों से अधिक नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, अल्सर, गंभीर एलर्जी प्रतिक्रिया, लीवर और किडनी की समस्या शामिल हो सकती है। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। इसे भोजन या दूध के साथ लें। इस दवा के साथ शराब का सेवन न करें। यदि आपको पेट अल्सर, किडनी, लीवर या हृदय रोग है तो डॉक्टर को बताएं। 7 दिनों से अधिक उपयोग से पहले डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 aciz mr tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after surgery.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Reduces pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps alleviate pain and swelling in rheumatoid arthritis as part of a comprehensive treatment plan.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Fever","description":"Paracetamol component may reduce fever, but combination is not primarily indicated for fever alone.","evidence":"Limited"}]
Primary treatment for: Acute musculoskeletal pain
Also treats: Osteoarthritis, Rheumatoid arthritis, Dental pain, Post-operative pain, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Aceclofenac + Paracetamol |
| Brand Name | Aldigesic P |
| Manufacturer | Ritz Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, leading to decreased synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and modulating pain perception, and it also affects the hypothalamic heat-regulating center to reduce fever. The combination provides enhanced analgesic and anti-inflammatory effects compared to either agent alone.
Mechanism Steps
💡 How to Take aciz mr tablet
Strength: Tablet containing Aceclofenac 250 mg and Paracetamol 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once or twice daily, preferably with food. The exact dose and duration must be individualized by a qualified clinician based on the indication, severity of pain, age, weight, renal and hepatic function, and response to treatment. Do not exceed the recommended dose. For acute pain, it is usually taken for short periods (up to 7 days) unless otherwise directed. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially gastrointestinal and renal side effects. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose of this medicine is generally one tablet twice daily, but must not exceed the dose prescribed by your doctor. Do not exceed 2 tablets in 24 hours. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of aciz mr tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| SSRIs | Moderate | |
| Oral hypoglycemics | Moderate | |
| Phenytoin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (e.g., ACE inhibitors, ARBs, diuretics)
- SSRIs
- Oral hypoglycemics
- Phenytoin
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding, ulceration, and liver damage, especially with paracetamol. It may also enhance the sedative effects of the medicine, leading to increased drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Aceclofenac, Paracetamol, or any component of the formulation","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe hepatic impairment","Severe renal impairment","Third trimester of pregnancy","Children under 14 years of age (unless directed by a pediatrician)"]
⚠️ Warnings & Precautions
["Take with food to minimize gastrointestinal irritation.","Avoid alcohol consumption.","Do not exceed the recommended dose or duration.","Use with caution in elderly patients.","Use with caution in patients with cardiovascular risk factors.","Use with caution in patients with asthma.","Use with caution in patients with kidney or liver disease.","Do not use for more than 7 days without medical advice.","Inform your doctor about all other medications you are taking.","Keep out of reach of children."]
🤱 Lactation Safety
Aceclofenac and Paracetamol are excreted in breast milk in small amounts. Paracetamol is generally considered safe during breastfeeding when used at recommended doses. Aceclofenac is not recommended during breastfeeding due to lack of sufficient data. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, abdominal pain, drowsiness, and liver damage (due to paracetamol). In case of overdose, seek immediate medical attention. Treatment includes supportive care, gastric lavage if within 1-2 hours of ingestion, and administration of N-acetylcysteine as an antidote for paracetamol toxicity. Monitor liver and kidney function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Always take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding and liver damage. Do not take other pain relievers or NSAIDs without consulting your doctor. If you have a history of stomach ulcers, kidney disease, liver disease, or heart problems, inform your doctor before taking this medicine. Do not use this medicine for more than 7 days without medical advice. Keep out of reach of children. Store at room temperature away from direct sunlight and moisture.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal, renal, and cardiovascular side effects. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly. Avoid concurrent use with other NSAIDs or anticoagulants.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like Aceclofenac may affect ovulation and are generally avoided during pregnancy, especially in the third trimester. Paracetamol is considered relatively safe but should be used at the lowest effective dose for the shortest time.
🏥 Post-Surgery Considerations
This medicine may be prescribed for post-operative pain. Take it exactly as directed by your surgeon. Inform your surgeon about all other medications you are taking. Do not use it for prolonged periods without medical advice.
🦷 Dental Procedures
This medicine can be used for dental pain relief. Inform your dentist if you are taking this medicine before any dental procedure. It may increase bleeding risk during dental surgery, so your dentist may need to adjust your medication.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you have pain, consult your doctor or physiotherapist for appropriate exercise modifications.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take breaks and stay hydrated. Inform your employer if you need any accommodations.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience any serious side effects such as gastrointestinal bleeding, severe allergic reactions, or signs of liver or kidney problems. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, liver damage, and cardiovascular events. Regular monitoring of liver and kidney function is recommended for prolonged use. It is advisable to use the lowest effective dose for the shortest duration. Consult your doctor if you need to take it for more than 7 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedApplying heat or cold packs can help reduce pain and inflammation.
Evidence: ModerateMay provide pain relief for some individuals.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust dosing times gradually to maintain consistent intervals. Check customs regulations for carrying prescription medicines. Always keep it in your carry-on luggage if flying. Do not leave it in a hot car or checked baggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it orally.
A: It is best taken with food or milk to reduce the risk of stomach upset and irritation.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, avoid alcohol while taking this medicine as it increases the risk of liver damage and gastrointestinal bleeding.
A: Consult your doctor before taking this medicine during pregnancy. It is generally avoided, especially in the third trimester.
A: It is usually prescribed for short-term use (up to 7 days). Do not use it for longer without consulting your doctor.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach irritation. - Myth: It is safe to take this medicine for long periods without monitoring.
Fact: Long-term use requires medical supervision and monitoring of liver and kidney function. - Myth: This medicine is safe to take with other painkillers.
Fact: Combining with other NSAIDs or paracetamol can increase the risk of side effects. - Myth: This medicine is safe during pregnancy.
Fact: It should be avoided, especially in the third trimester, unless prescribed by a doctor.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 250 mg + Paracetamol 100 mg tablet (various manufacturers)
Brand Alternatives
- Aciz MR Tablet