acitak 300 mg tablet - Cimetidine (300mg) medicine

Acitak 300 mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Astron Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is acitak 300 mg tablet used for?

Acitak 300 mg Tablet contains Cimetidine, an H2 blocker that reduces stomach acid production. It is used to treat and prevent stomach and intestinal ulcers, gastroesophageal reflux disease (GERD), and conditions where the stomach produces too much acid. It works by blocking histamine receptors in the stomach lining, decreasing acid secretion.

  • Generic Name: Cimetidine
  • Manufacturer: Astron Healthcare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š acitak 300 mg tablet Uses & Benefits

Duodenal ulcer, gastric ulcer, gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, prevention of stress ulcers, prophylaxis of aspiration pneumonitis.

Off-label uses: Hirsutism (due to antiandrogen effects), chronic urticaria, adjunct in cancer immunotherapy (due to immunomodulation).

๐Ÿ“‹ Drug Information

Generic Name(s)Cimetidine
Brand NameAcitak
ManufacturerAstron Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassH2 Receptor Blocker
Route of AdministrationOral, intravenous, intramuscular.
StorageStore at room temperature (20-25ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentrations achieved within 1-2 hours.
DistributionWidely distributed throughout body tissues; crosses the blood-brain barrier and placenta.
Protein BindingApproximately 20% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via oxidation, hydroxylation, and sulfoxidation.
Half-LifeApproximately 2 hours (normal renal function); prolonged in renal impairment.
ExcretionPrimarily excreted in urine (50-70% as unchanged drug and metabolites); some biliary excretion.
BioavailabilityApproximately 60-70% after oral administration.
Onset of ActionWithin 1 hour after oral administration.
Peak Plasma Time1-2 hours after oral administration.
Duration of Action4-6 hours (dose-dependent).

How It Works

Competitive antagonist of histamine at H2 receptors, reducing gastric acid secretion.

Mechanism Steps

1Cimetidine binds competitively to histamine H2 receptors on gastric parietal cells.
2Blockade of H2 receptors inhibits adenylate cyclase activity, reducing cyclic AMP production.
3Decreased cyclic AMP leads to reduced activation of protein kinase A.

๐Ÿ’ก How to Take acitak 300 mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of acitak 300 mg tablet

โœ… Common Side Effects

  • Headache
  • Dizziness
  • Diarrhea
  • Constipation
  • Nausea
  • Vomiting
  • Rash

๐Ÿšจ Serious Side Effects

  • Confusion
  • Hallucinations
  • Seizures
  • Arrhythmias
  • Hepatitis
  • Interstitial nephritis
  • Agranulocytosis
  • Thrombocytopenia
  • Pancreatitis

โš ๏ธ Rare Side Effects

  • Gynecomastia
  • Impotence
  • Loss of libido
  • Alopecia
  • Myalgia
  • Arthralgia
  • Fever

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Moderate Increased INR and bleeding risk
Ketoconazole Moderate Decreased absorption of ketoconazole
Sucralfate Minor Reduced absorption of cimetidine

๐Ÿšจ Major Interactions

  • Warfarin
  • Theophylline
  • Phenytoin
  • Lidocaine
  • Quinidine
  • Propranolol
  • Metoprolol
  • Carbamazepine
  • Tricyclic antidepressants
  • Benzodiazepines (e.g., diazepam, chlordiazepoxide)

โšก Moderate Interactions

  • Calcium channel blockers (e.g., nifedipine)
  • Sulfonylureas (e.g., glipizide)
  • Metformin
  • Procainamide
  • Flecainide
  • Morphine
  • Caffeine
  • Alcohol

โ„น๏ธ Minor Interactions

  • Antacids
  • Sucralfate
  • Ketoconazole
  • Itraconazole
  • Tetracyclines
  • Iron supplements

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but does not significantly affect bioavailability; avoid high-protein meals as they may increase gastric acid stimulation.

๐Ÿท Alcohol Interaction

Cimetidine may increase blood alcohol levels by inhibiting alcohol dehydrogenase; avoid alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to cimetidine or any component; use with caution in elderly, renal impairment, hepatic impairment.

๐Ÿ“Š Monitoring Parameters

Gastric pH, renal function, hepatic function, CBC, drug levels for interacting medications (e.g., warfarin, theophylline).

๐Ÿคฑ Lactation Safety

Cimetidine is excreted in breast milk; caution advised; alternative agents preferred.

๐Ÿ’Š Overdose Management

Supportive care; activated charcoal if recent ingestion; monitor vital signs and ECG; dialysis may be effective.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

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