aciop dsr capsule - Domperidone (10mg) + Omeprazole (20mg) medicine

aciop dsr capsule

4.6 (16 reviews)
๐Ÿญ Bennet Pharmaceuticals Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is aciop dsr capsule used for?

Aciloc RD 20 Tablet (Domperidone + Omeprazole) is used to treat GASTRO INTESTINAL. It contains Domperidone (10mg) + Omeprazole (20mg), which Domperidone is a dopamine D2 receptor antagonist that enhances gastrointestinal . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Domperidone + Omeprazole
  • Manufacturer: Bennet Pharmaceuticals Limited
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š aciop dsr capsule Uses & Benefits

Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, peptic ulcer disease.

Off-label uses: Nausea and vomiting of various etiologies, migraine-associated gastroparesis.

๐Ÿ“‹ Drug Information

Generic Name(s)Domperidone + Omeprazole
Brand NameAciloc RD 20 Tablet
ManufacturerBennet Pharmaceuticals Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassProkinetic agent + Proton pump inhibitor
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionDomperidone: Rapidly absorbed after oral administration; Omeprazole: Rapidly absorbed, delayed by food.
DistributionDomperidone: Widely distributed, crosses blood-brain barrier minimally; Omeprazole: High plasma protein binding, distributed to gastric parietal cells.
Protein BindingDomperidone: 91-93%; Omeprazole: 95%
MetabolismDomperidone: Hepatic via CYP3A4; Omeprazole: Hepatic via CYP2C19 and CYP3A4.
Half-LifeDomperidone: 7-9 hours; Omeprazole: 0.5-1 hour.
ExcretionDomperidone: Fecal (66%) and renal (32%); Omeprazole: Renal (77%) and fecal.
BioavailabilityDomperidone: 13-17%; Omeprazole: 30-40%.
Onset of ActionDomperidone: 30-60 minutes; Omeprazole: 1-2 hours.
Peak Plasma TimeDomperidone: 1-2 hours; Omeprazole: 0.5-3.5 hours.
Duration of ActionDomperidone: 4-6 hours; Omeprazole: Up to 24 hours.

How It Works

Domperidone is a dopamine D2 receptor antagonist that enhances gastrointestinal motility; Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in parietal cells.

Mechanism Steps

1Domperidone blocks dopamine D2 receptors in the chemoreceptor trigger zone and gastrointestinal tract, increasing peristalsis and gastric emptying.
2Omeprazole accumulates in the acidic environment of gastric parietal cells and is converted to its active form, which irreversibly inhibits H+/K+ ATPase, reducing gastric acid secretion.

๐Ÿ’ก How to Take aciop dsr capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of aciop dsr capsule

โœ… Common Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Flatulence
  • Dry mouth

๐Ÿšจ Serious Side Effects

  • QT prolongation
  • Torsades de pointes
  • Extrapyramidal symptoms
  • Gynecomastia
  • Hyperprolactinemia
  • Interstitial nephritis

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Anaphylaxis
  • Agranulocytosis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Major Increased risk of QT prolongation
Warfarin Moderate Increased INR and bleeding risk
Sucralfate Minor Reduced absorption of omeprazole

๐Ÿšจ Major Interactions

  • Ketoconazole
  • Itraconazole
  • Voriconazole
  • Clarithromycin
  • Erythromycin
  • Ritonavir
  • Saquinavir
  • Telithromycin
  • Nefazodone
  • Cobicistat

โšก Moderate Interactions

  • Warfarin
  • Cilostazol
  • Methotrexate
  • Tacrolimus
  • Fluconazole
  • Cimetidine
  • Digoxin
  • Iron salts
  • Mycophenolate mofetil

โ„น๏ธ Minor Interactions

  • Sucralfate
  • Antacids
  • Theophylline
  • Caffeine

๐Ÿฝ๏ธ Food Interactions

Omeprazole absorption may be delayed by food; Domperidone should be taken before meals.

๐Ÿท Alcohol Interaction

Alcohol may worsen gastrointestinal irritation and reduce drug efficacy.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to components, gastrointestinal hemorrhage, mechanical obstruction or perforation, prolactinoma, concurrent use with QT-prolonging drugs.

๐Ÿ“Š Monitoring Parameters

ECG for QT interval, renal function, liver function, serum electrolytes, signs of extrapyramidal symptoms.

๐Ÿคฑ Lactation Safety

Domperidone is excreted in breast milk; omeprazole is likely excreted. Use with caution.

๐Ÿ’Š Overdose Management

Supportive care; ECG monitoring for QT prolongation; activated charcoal if recent ingestion.

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip missed dose if close to next scheduled dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

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