Acigol D 10mg/20mg Capsule - Uses, Price, Side Effects
What is acigol d 10mg/20mg capsule used for?
Acigol D 10mg/20mg Capsule is a combination medicine used to treat gastroesophageal reflux disease (GERD) and acidity. It contains Domperidone, which helps control vomiting and nausea by increasing stomach movement, and Omeprazole, which reduces stomach acid production. This helps relieve heartburn, acid reflux, and indigestion.
- Generic Name: Domperidone + Omeprazole
- Manufacturer: Saffron Medicare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ acigol d 10mg/20mg capsule Uses & Benefits
Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, peptic ulcer disease.
Off-label uses: Nausea and vomiting of various etiologies, migraine-associated gastroparesis.
๐ Drug Information
| Generic Name(s) | Domperidone + Omeprazole |
| Brand Name | Aciloc RD 20 Tablet |
| Manufacturer | Saffron Medicare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Domperidone is a dopamine D2 receptor antagonist that enhances gastrointestinal motility; Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in parietal cells.
Mechanism Steps
๐ก How to Take acigol d 10mg/20mg capsule
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of acigol d 10mg/20mg capsule
โ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Flatulence
- Dry mouth
๐จ Serious Side Effects
- QT prolongation
- Torsades de pointes
- Extrapyramidal symptoms
- Gynecomastia
- Hyperprolactinemia
- Interstitial nephritis
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Anaphylaxis
- Agranulocytosis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Increased risk of bleeding |
| Ketoconazole | Major | Increased risk of QT prolongation |
| Digoxin | Moderate | Increased digoxin levels |
๐จ Major Interactions
- Ketoconazole
- Itraconazole
- Voriconazole
- Clarithromycin
- Erythromycin
- Ritonavir
- Saquinavir
- Telithromycin
- Nefazodone
- Cobicistat
โก Moderate Interactions
- Warfarin
- Cilostazol
- Methotrexate
- Tacrolimus
- Fluconazole
- Cimetidine
- Digoxin
- Iron salts
- Mycophenolate mofetil
โน๏ธ Minor Interactions
- Sucralfate
- Antacids
- Theophylline
- Caffeine
๐ฝ๏ธ Food Interactions
Omeprazole absorption may be delayed by food; Domperidone should be taken before meals.
๐ท Alcohol Interaction
Alcohol may worsen gastrointestinal irritation and reduce drug efficacy.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components, gastrointestinal hemorrhage, mechanical obstruction or perforation, prolactinoma, concurrent use with QT-prolonging drugs.
๐ Monitoring Parameters
ECG for QT interval, renal function, liver function, serum electrolytes, signs of extrapyramidal symptoms.
๐คฑ Lactation Safety
Domperidone is excreted in breast milk; omeprazole is likely excreted. Use with caution.
๐ Overdose Management
Supportive care; ECG monitoring for QT prolongation; activated charcoal if recent ingestion.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next scheduled dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.