Acidrim Tablet - Uses, Price, Side Effects
What is acidrim tablet used for?
Acidrim Tablet is a combination medicine containing Domperidone (10mg) and Omeprazole (20mg). It is used to treat acidity, heartburn, and gastroesophageal reflux disease (GERD). Omeprazole reduces stomach acid production, while Domperidone helps prevent nausea and improves gastric emptying, providing comprehensive relief from digestive discomfort.
- Generic Name: Domperidone + Omeprazole
- Manufacturer: Dial Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ acidrim tablet Uses & Benefits
Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, peptic ulcer disease.
Off-label uses: Nausea and vomiting of various etiologies, migraine-associated gastroparesis.
๐ Drug Information
| Generic Name(s) | Domperidone + Omeprazole |
| Brand Name | Aciloc RD 20 Tablet |
| Manufacturer | Dial Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Domperidone is a dopamine D2 receptor antagonist that enhances gastrointestinal motility; Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in parietal cells.
Mechanism Steps
๐ก How to Take acidrim tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of acidrim tablet
โ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Flatulence
- Dry mouth
๐จ Serious Side Effects
- QT prolongation
- Torsades de pointes
- Extrapyramidal symptoms
- Gynecomastia
- Hyperprolactinemia
- Interstitial nephritis
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Anaphylaxis
- Agranulocytosis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Ketoconazole | Moderate | Increased risk of QT prolongation |
| Digoxin | Moderate | Increased digoxin levels |
๐จ Major Interactions
- Ketoconazole
- Itraconazole
- Voriconazole
- Clarithromycin
- Erythromycin
- Ritonavir
- Saquinavir
- Telithromycin
- Nefazodone
- Cobicistat
โก Moderate Interactions
- Warfarin
- Cilostazol
- Methotrexate
- Tacrolimus
- Fluconazole
- Cimetidine
- Digoxin
- Iron salts
- Mycophenolate mofetil
โน๏ธ Minor Interactions
- Sucralfate
- Antacids
- Theophylline
- Caffeine
๐ฝ๏ธ Food Interactions
Omeprazole absorption may be delayed by food; Domperidone should be taken before meals.
๐ท Alcohol Interaction
Alcohol may worsen gastrointestinal irritation and reduce drug efficacy.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components, gastrointestinal hemorrhage, mechanical obstruction or perforation, prolactinoma, concurrent use with QT-prolonging drugs.
๐ Monitoring Parameters
ECG for QT interval, renal function, liver function, serum electrolytes, signs of extrapyramidal symptoms.
๐คฑ Lactation Safety
Domperidone is excreted in breast milk; omeprazole is likely excreted. Use with caution.
๐ Overdose Management
Supportive care; ECG monitoring for QT prolongation; activated charcoal if recent ingestion.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next scheduled dose.