acidof 20mg capsule - Omeprazole (20mg) medicine

Acidof 20mg Capsule - Uses, Price, Side Effects

4.4 (11 reviews)

Omeprazole (20mg)

🏭 Chemo Biological 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is acidof 20mg capsule used for?

Acidof 20mg Capsule contains Omeprazole, a proton pump inhibitor that reduces stomach acid production. It is used to treat gastroesophageal reflux disease (GERD), heartburn, acid indigestion, and stomach ulcers. It works by blocking the enzyme in the stomach wall that produces acid, providing relief from symptoms and promoting healing.

Generic Name: Omeprazole
Manufacturer: Chemo Biological
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 acidof 20mg capsule Uses & Benefits

Gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, Helicobacter pylori eradication (combination therapy), peptic ulcer disease, dyspepsia.

Off-label uses: Stress ulcer prophylaxis, eosinophilic esophagitis, laryngopharyngeal reflux, prevention of NSAID-induced ulcers.

📋 Drug Information

Generic Name(s)	Omeprazole
Brand Name	Acid 20 Capsule
Manufacturer	Chemo Biological
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	GASTRO INTESTINAL
Action Class	Proton pump inhibitors
Route of Administration	Oral.
Storage	Store at room temperature (20-25°C); protect from moisture and light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentration achieved within 0.5-3.5 hours.

DistributionVolume of distribution approximately 0.3 L/kg; extensively distributed into tissues.

Protein BindingApproximately 95% bound to plasma proteins (mainly albumin).

MetabolismExtensively metabolized in the liver by CYP2C19 and CYP3A4; major metabolites are omeprazole sulfone and hydroxyomeprazole.

Half-LifeApproximately 0.5-1 hour (healthy subjects); may be prolonged in hepatic impairment.

ExcretionAbout 80% excreted in urine as metabolites, remainder in feces.

BioavailabilityOral bioavailability approximately 30-40% (increases with repeated dosing).

Onset of ActionWithin 1 hour; maximal effect after 2-4 days.

Peak Plasma Time0.5-3.5 hours.

Duration of ActionUp to 24 hours (acid suppression).

How It Works

Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells.

Mechanism Steps

1Omeprazole is a weak base that accumulates in the acidic environment of gastric parietal cell canaliculi.

2It is protonated and converted to the active sulfenamide form.

3The active form binds covalently to cysteine residues on the H+/K+ ATPase (proton pump).

💡 How to Take acidof 20mg capsule

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⚠️ Side Effects of acidof 20mg capsule

✅ Common Side Effects

Headache
Abdominal pain
Nausea
Diarrhea
Constipation
Flatulence

🚨 Serious Side Effects

Clostridium difficile-associated diarrhea
Bone fracture (hip, wrist, spine)
Hypomagnesemia
Vitamin B12 deficiency
Acute interstitial nephritis
Cutaneous lupus erythematosus
Severe cutaneous adverse reactions (SJS, TEN)

⚠️ Rare Side Effects

Hepatotoxicity
Pancreatitis
Anaphylaxis
Angioedema
Bronchospasm
Agranulocytosis
Pancytopenia
Gynecomastia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Clopidogrel	Moderate	Reduced antiplatelet effect
Methotrexate	Major	Increased methotrexate toxicity
Digoxin	Moderate	Increased digoxin levels
Ketoconazole	Moderate	Reduced ketoconazole absorption

🚨 Major Interactions

Clopidogrel
Methotrexate
Cilostazol
Rilpivirine
Erlotinib

⚡ Moderate Interactions

Warfarin
Phenytoin
Diazepam
Citalopram
Escitalopram
Tacrolimus
Mycophenolate mofetil

ℹ️ Minor Interactions

Digoxin
Iron salts
Ketoconazole
Itraconazole
Ampicillin esters

🍽️ Food Interactions

Food delays absorption but does not affect extent; best taken before meals.

🍷 Alcohol Interaction

No significant interaction; alcohol may worsen gastric irritation.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to omeprazole or any component; concomitant use with rilpivirine.

📊 Monitoring Parameters

Assess for symptom relief; monitor liver function tests if prolonged use; consider bone density monitoring for long-term use; check magnesium levels if prolonged use.

🤱 Lactation Safety

Excreted in breast milk; caution advised.

💊 Overdose Management

Supportive care; symptoms may include confusion, drowsiness, blurred vision, tachycardia, nausea, vomiting, diaphoresis, flushing, headache, dry mouth. Hemodialysis not effective.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for acidof 20mg capsule

View All

Alternative brands with exact same active ingredient (Omeprazole (20mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026