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aceta 250mg tablet sr

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Acetazolamide (250mg)

🏭 Mmatrics Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Jul 4, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Jul 04, 2026

What is aceta 250mg tablet sr used for?

Acetamide (Acetazolamide) is used to treat OPHTHAL. It contains Acetazolamide (250mg), which Inhibits carbonic anhydrase, reducing aqueous humor production in the eye and de. Always consult your doctor before use. Take as prescribed.

Generic Name: Acetazolamide
Manufacturer: Mmatrics Pharmaceuticals
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 aceta 250mg tablet sr Uses & Benefits

Glaucoma (open-angle and secondary); prevention of acute mountain sickness; epilepsy (adjunctive); idiopathic intracranial hypertension; metabolic alkalosis; cystinuria; periodic paralysis.

Off-label uses: Altitude sickness prophylaxis; sleep apnea; glaucoma in dogs; pseudotumor cerebri; diuretic in heart failure (rare).

📋 Drug Information

Generic Name(s)	Acetazolamide
Brand Name	Acetamide
Manufacturer	Mmatrics Pharmaceuticals
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	OPHTHAL
Action Class	Carbonic anhydrase inhibitor
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from gastrointestinal tract after oral administration.

DistributionDistributes into erythrocytes, kidneys, and other tissues; crosses placenta and enters breast milk.

Protein Binding70-90%

MetabolismNot significantly metabolized; excreted unchanged in urine.

Half-Life10-15 hours

ExcretionRenal excretion (90% unchanged)

Bioavailability~100%

Onset of Action1-1.5 hours (oral)

Peak Plasma Time2-4 hours

Duration of Action8-12 hours

How It Works

Inhibits carbonic anhydrase, reducing aqueous humor production in the eye and decreasing intraocular pressure.

Mechanism Steps

1Inhibition of carbonic anhydrase in ciliary processes of the eye

2Reduced formation of bicarbonate ions

3Decreased aqueous humor secretion

💡 How to Take aceta 250mg tablet sr

Follow your doctor's prescription exactly.

⚠️ Side Effects of aceta 250mg tablet sr

✅ Common Side Effects

Paresthesia
Taste alteration (metallic taste)
Nausea
Vomiting
Diarrhea
Polyuria
Drowsiness
Confusion

🚨 Serious Side Effects

Stevens-Johnson syndrome
Toxic epidermal necrolysis
Aplastic anemia
Agranulocytosis
Thrombocytopenia
Metabolic acidosis
Hypokalemia
Renal calculi
Hepatic necrosis

⚠️ Rare Side Effects

Photosensitivity
Hearing loss
Tinnitus
Transient myopia
Flaccid paralysis
Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk due to displacement from protein binding.
Lithium	Major	Increased lithium toxicity due to decreased excretion.
Cyclosporine	Major	Increased nephrotoxicity risk.
Methotrexate	Major	Increased methotrexate toxicity due to decreased renal clearance.
Primidone	Major	Decreased primidone efficacy; increased seizure risk.
Aspirin	Moderate	Increased risk of metabolic acidosis and salicylate toxicity.
Digoxin	Moderate	Increased digoxin toxicity due to hypokalemia.
Phenytoin	Moderate	Increased phenytoin toxicity due to decreased metabolism.
Quinidine	Moderate	Increased quinidine toxicity due to decreased excretion.
Corticosteroids	Minor	Increased risk of hypokalemia.
Amphotericin B	Minor	Increased risk of hypokalemia and nephrotoxicity.
Metformin	Minor	Increased risk of lactic acidosis.

🚨 Major Interactions

Warfarin
Lithium
Cyclosporine
Methotrexate
Primidone

⚡ Moderate Interactions

Aspirin
Salicylates
Digoxin
Phenytoin
Quinidine

ℹ️ Minor Interactions

Corticosteroids
Amphotericin B
Metformin

🍽️ Food Interactions

High-fat meals may delay absorption; avoid excessive sodium intake.

🍷 Alcohol Interaction

May increase risk of metabolic acidosis and dizziness.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to acetazolamide or sulfonamides; severe hepatic or renal impairment; hyponatremia; hypokalemia; hyperchloremic acidosis; Addison's disease; long-term use in chronic noncongestive angle-closure glaucoma.

📊 Monitoring Parameters

Intraocular pressure; serum electrolytes (especially potassium and bicarbonate); renal function; liver function; complete blood count; urinary output.

🤱 Lactation Safety

Use with caution; excreted in breast milk.

💊 Overdose Management

Induce emesis or gastric lavage; monitor electrolytes and acid-base balance; treat metabolic acidosis with sodium bicarbonate if severe; supportive care.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Jul 04, 2026

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🔄 Substitutes for aceta 250mg tablet sr

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Alternative brands with exact same active ingredient (Acetazolamide (250mg)):

Medical Note: Always consult your doctor before switching medications.

😊 Was this information helpful?

📌 Quick Facts

Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Route	Oral
Pregnancy	Category C
Breastfeeding	Use with caution; excreted in breast milk.
Alcohol	May increase risk of metabolic acidosis and dizziness.
Onset of Action	1-1.5 hours (oral)
Half-Life	10-15 hours
Prescription	✅ Required

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