iomide 250mg tablet - Acetazolamide (250mg) medicine

Iopar-SR Capsule (Acetazolamide 250 mg): Complete Medicine Guide

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🏭 Hicare Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for glaucoma, edema, epilepsy, and acute mountain sickness.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Rash, blisters, or peeling skin
  • Unusual bleeding or bruising
  • Severe abdominal pain or blood in vomit or stool
  • Confusion, rapid breathing, or irregular heartbeat
  • Decreased urine output or swelling in legs
  • Severe headache with vision changes
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is iomide 250mg tablet used for?

This medicine contains Acetazolamide 250 mg, a carbonic anhydrase inhibitor used to treat glaucoma, edema, epilepsy, and acute mountain sickness. It works by reducing fluid production in the eye and acting as a mild diuretic. It is a prescription medicine and should be taken exactly as directed by your doctor.

  • Generic Name: Acetazolamide (250mg)
  • Manufacturer: Hicare Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 iomide 250mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एसिटाजोलामाइड 250 मिलीग्राम कैप्सूल है, जिसका उपयोग मुख्य रूप से ग्लूकोमा (आंखों में बढ़े हुए दबाव) को कम करने के लिए किया जाता है। यह शरीर में अतिरिक्त तरल पदार्थ को बाहर निकालने में मदद करती है और कुछ प्रकार के दौरे (मिर्गी) और ऊंचाई पर होने वाली बीमारी (अल्टीट्यूड सिकनेस) के इलाज और रोकथाम में भी उपयोग की जाती है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में हाथ-पैरों में झुनझुनी या सुन्नपन, बार-बार पेशाब आना, चक्कर आना, नींद आना, जी मिचलाना, उल्टी, दस्त और मुंह में धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन त्वचा पर गंभीर दाने, खून की बीमारी, गुर्दे की पथरी, मेटाबॉलिक एसिडोसिस और एलर्जी प्रतिक्रिया हो सकती है। यदि आपको त्वचा पर दाने, असामान्य रक्तस्राव, गंभीर पेट दर्द, भ्रम या तेज धड़कन महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुद से खुराक न बदलें और न ही दवा बंद करें। दिन भर पर्याप्त पानी पिएं ताकि गुर्दे की पथरी से बचाव हो सके। इस दवा के साथ शराब न लें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। धूप में बाहर निकलते समय सनस्क्रीन और सुरक्षात्मक कपड़े पहनें। नियमित जांच के लिए डॉक्टर के पास जाते रहें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 iomide 250mg tablet Uses & Benefits

[{"condition":"Glaucoma (open-angle and secondary)","description":"Lowers elevated intraocular pressure by reducing aqueous humor production, helping to prevent optic nerve damage.","evidence":"Well-established"},{"condition":"Acute angle-closure glaucoma","description":"Used as an adjunct to other treatments to rapidly reduce intraocular pressure during an acute attack.","evidence":"Well-established"},{"condition":"Edema due to heart failure","description":"Acts as a mild diuretic to help remove excess fluid in selected patients when other diuretics are not suitable.","evidence":"Established"},{"condition":"Epilepsy (adjunctive therapy)","description":"May be added to other anti-seizure medicines for certain seizure types, especially absence seizures.","evidence":"Established"},{"condition":"Acute mountain sickness (prevention and treatment)","description":"Helps prevent and reduce symptoms of altitude sickness by stimulating breathing and reducing fluid buildup.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Idiopathic intracranial hypertension","description":"Sometimes prescribed to reduce cerebrospinal fluid production and lower intracranial pressure.","evidence":"Limited"},{"condition":"Metabolic alkalosis","description":"Occasionally used to correct certain types of metabolic alkalosis under specialist supervision.","evidence":"Limited"},{"condition":"Periodic paralysis","description":"May be used in some forms of periodic paralysis to prevent attacks, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Glaucoma

Also treats: Edema due to heart failure, Epilepsy, Acute mountain sickness

📋 Drug Information

Generic Name(s)Acetazolamide (250mg)
Brand Nameiomide 250mg tablet
ManufacturerHicare Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassCarbonic anhydrase inhibitor
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset and improve tolerability.
2
Drink plenty of water throughout the day to help prevent kidney stones.
3
Avoid alcohol while taking this medicine because it can increase drowsiness and dizziness.
4
Do not drive or operate heavy machinery until you know how this medicine affects you.
5
Monitor for tingling in hands and feet; this is usually harmless but report if severe.
6
Keep regular follow-up appointments for monitoring of electrolytes and kidney function.
7
Do not stop this medicine abruptly without consulting your doctor, especially if taking it for seizures.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Increased eye pressure (glaucoma)
This medicine is commonly prescribed for this.
Likely Use
✅
Fluid retention (edema)
This medicine may be used as a diuretic.
Likely Use
✅
Seizures
This medicine may be used as an adjunctive treatment.
Likely Use
✅
Altitude sickness
This medicine is used for prevention and treatment.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the gastrointestinal tract after oral administration. The exact bioavailability and absorption rate are not established from the available information.
DistributionThis medicine distributes into various body tissues, including the eye, kidney, and central nervous system. It crosses the placenta and is excreted in breast milk. The exact volume of distribution is not established from the available information.
Protein BindingThis medicine is highly bound to plasma proteins, primarily albumin. The exact percentage is not established from the available information.
MetabolismThis medicine is not significantly metabolized in the liver. It is excreted largely unchanged by the kidneys.
Half-LifeThe elimination half-life of this medicine is approximately 10 to 15 hours in individuals with normal kidney function. It may be prolonged in patients with kidney impairment.
ExcretionThis medicine is excreted primarily unchanged in the urine by renal tubular secretion and glomerular filtration. It is also excreted in breast milk.
BioavailabilityThe oral bioavailability of this medicine is not established from the available information.
Onset of ActionThe onset of action for lowering intraocular pressure is usually within 1 to 2 hours after oral administration. The diuretic effect begins within 1 to 2 hours.
Peak Plasma TimePeak plasma concentrations are typically reached within 1 to 3 hours after oral administration.
Duration of ActionThe duration of action for intraocular pressure reduction is approximately 8 to 12 hours. The diuretic effect lasts about 6 to 12 hours.

How It Works

This medicine works by inhibiting the enzyme carbonic anhydrase in various tissues. In the eye, this reduces the secretion of aqueous humor, which lowers intraocular pressure. In the kidney, it increases the excretion of bicarbonate, sodium, potassium, and water, producing a mild diuretic effect. In the brain, it may help reduce cerebrospinal fluid production and alter pH, which can help in conditions like altitude sickness and certain seizures.

Mechanism Steps

1
Enzyme binding: This medicine binds reversibly to the carbonic anhydrase enzyme, blocking its activity.
2
Reduced bicarbonate formation: Inhibition of carbonic anhydrase decreases the conversion of carbon dioxide and water into bicarbonate and hydrogen ions.
3
Decreased aqueous humor production: In the ciliary body of the eye, this reduces the secretion of aqueous humor, leading to lower intraocular pressure.
4
Diuretic effect: In the kidney, reduced bicarbonate reabsorption leads to increased excretion of sodium, potassium, bicarbonate, and water.
5
Metabolic acidosis: The loss of bicarbonate can cause a mild metabolic acidosis, which may contribute to some therapeutic effects and side effects.

💡 How to Take iomide 250mg tablet

Strength: Acetazolamide 250 mg immediate-release capsule

1Take this medicine exactly as prescribed by your doctor.
2Swallow the capsule whole with a full glass of water.
3Take with food to reduce stomach upset.
4Do not crush, chew, or open the capsule unless instructed by your doctor.
5Drink plenty of water throughout the day to help prevent kidney stones.
6Avoid alcohol while taking this medicine.
7If you miss a dose, follow the missed dose instructions provided.
8Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine for glaucoma is 250 mg to 1000 mg per day, divided into one to four doses, depending on the severity of the condition and patient response. For acute mountain sickness, 125 mg to 250 mg twice daily may be used, starting 24 hours before ascent. For epilepsy, the dose ranges from 250 mg to 1000 mg per day in divided doses. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and electrolyte imbalances. Dose should be individualized by a qualified clinician based on renal function and overall health status.
Renal ImpairmentThis medicine is excreted by the kidneys. In patients with renal impairment, the dose may need to be reduced. It is contraindicated in severe renal impairment. Consult a nephrologist or qualified clinician for individualized dosing.
Hepatic ImpairmentThis medicine is not significantly metabolized by the liver, but it should be used with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is 1000 mg, but this may vary based on indication and clinical judgment. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
High-sodium foods
Limit intake
May reduce the effectiveness of this medicine.
Potassium-rich foods
Include in moderation
Helps prevent potassium loss caused by this medicine.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of iomide 250mg tablet

✅ Common Side Effects

Tingling or numbness in hands and feet (Common (up to 10%))
Usually harmless and may decrease over time. If it becomes bothersome or persistent, consult your doctor.
Increased urination (Common (up to 10%))
Drink plenty of water and avoid taking the dose close to bedtime if it interferes with sleep.
Dizziness or drowsiness (Common (up to 10%))
Avoid driving or operating machinery until you know how this medicine affects you. Rise slowly from sitting or lying positions.
Nausea, vomiting, or diarrhea (Common (up to 10%))
Take with food to reduce stomach upset. If symptoms are severe or persistent, contact your doctor.
Metallic taste in mouth (Common (up to 10%))
This usually resolves on its own. Chewing sugar-free gum or rinsing your mouth may help.

🚨 Serious Side Effects

Severe skin reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis) (Rare (<0.1%))
Seek immediate medical attention if you develop a rash, blisters, peeling skin, or sores in the mouth or eyes.
Blood disorders (e.g., aplastic anemia, agranulocytosis) (Rare (<0.1%))
Report unusual tiredness, fever, sore throat, or easy bruising or bleeding to your doctor immediately.
Kidney stones (Uncommon (0.1-1%))
Drink plenty of water. Seek medical attention if you experience severe back or side pain, blood in urine, or painful urination.
Metabolic acidosis (Uncommon (0.1-1%))
Contact your doctor if you experience rapid breathing, confusion, extreme tiredness, or irregular heartbeat.
Severe allergic reactions (anaphylaxis) (Rare (<0.1%))
Seek emergency help if you have difficulty breathing, swelling of the face, lips, tongue, or throat, or a severe rash.

⚠️ Rare Side Effects

Hepatic insufficiency
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Photosensitivity
Use sunscreen and protective clothing when outdoors. Consult your doctor if you notice unusual skin reactions.
Flaccid paralysis
Seek immediate medical attention if you experience sudden weakness or inability to move parts of your body.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Salicylates Major
Lithium Major
Primidone Major
Amphetamines Major
Memantine Major
Corticosteroids Moderate
Diuretics Moderate
Digoxin Moderate
Methenamine Moderate
Carbamazepine Moderate

🚨 Major Interactions

  • Salicylates (e.g., high-dose aspirin)
  • Lithium
  • Primidone
  • Amphetamines
  • Memantine

⚡ Moderate Interactions

  • Corticosteroids
  • Diuretics (e.g., thiazides, loop diuretics)
  • Digoxin
  • Methenamine
  • Carbamazepine

🍷 Alcohol Interaction

Alcohol may increase the central nervous system side effects of this medicine, such as dizziness and drowsiness. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to acetazolamide or sulfonamides","Severe renal impairment or kidney failure","Severe hepatic impairment or cirrhosis","Hyperchloremic acidosis","Hypokalemia or hyponatremia","Adrenal insufficiency","Pregnancy (especially first trimester) unless clearly needed"]

⚠️ Warnings & Precautions

["This medicine may cause drowsiness and blurred vision. Avoid driving or operating machinery until you know how it affects you.","Drink plenty of water to prevent kidney stones.","This medicine may increase sensitivity to sunlight. Use sunscreen and protective clothing.","Monitor for signs of metabolic acidosis, such as rapid breathing, confusion, and fatigue.","Use with caution in patients with respiratory disease, especially chronic obstructive pulmonary disease, as it may cause acidosis.","This medicine may cause a decrease in blood counts. Report any signs of infection or unusual bleeding.","Do not use this medicine for prolonged periods without medical supervision."]

🤱 Lactation Safety

This medicine is excreted in breast milk. It is not known whether it affects the breastfed infant. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose of this medicine may cause severe metabolic acidosis, electrolyte imbalances, and central nervous system effects. Seek immediate medical attention. Treatment is supportive and symptomatic, including monitoring of vital signs, electrolytes, and blood gases. Hemodialysis may be considered in severe cases.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Drink plenty of water throughout the day to help prevent kidney stones. Avoid alcohol while taking this medicine because it can increase drowsiness and dizziness. Tell your doctor if you have kidney or liver problems, low potassium or sodium levels, or a history of kidney stones. This medicine may make your skin more sensitive to sunlight, so use sunscreen and protective clothing when outdoors. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before using this medicine. Keep all follow-up appointments so your doctor can monitor your blood counts, electrolyte levels, and kidney function.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and electrolyte imbalances. Dose should be individualized based on renal function and overall health status. Regular monitoring is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed. Discuss alternative treatments if appropriate.

🏥 Post-Surgery Considerations

This medicine may interact with other medicines used during surgery. Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before certain surgeries.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or increased bleeding risk. Your dentist may need to take precautions.

💚 Lifestyle Tips for Better Results

🏃
Drink plenty of water throughout the day to prevent kidney stones.
🥗
Avoid alcohol while taking this medicine.
😴
Use sunscreen and protective clothing when outdoors due to increased sun sensitivity.
💧
Maintain a balanced diet rich in potassium to prevent electrolyte imbalances.
🧘
Follow up regularly with your doctor for monitoring.
🌞
Avoid driving or operating machinery until you know how this medicine affects you.

🏋️ Exercise Considerations

This medicine may cause dizziness and drowsiness. Avoid strenuous exercise or activities that require mental alertness until you know how it affects you. Stay hydrated during exercise.

🥗 Diet Recommendations

Include potassium-rich foods like bananas, oranges, and potatoes.
Limit high-sodium foods.
Stay well hydrated.
Avoid alcohol.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, dizziness, and blurred vision, which can affect your ability to drive or operate machinery. It may also cause increased urination, which can be inconvenient during work hours. Plan your doses accordingly and consult your doctor if side effects interfere with your daily activities.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your condition worsens, contact your doctor immediately. Your doctor will determine if and when to stop the medicine.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to electrolyte imbalances, metabolic acidosis, kidney stones, and blood disorders. Regular monitoring of blood counts, electrolytes, and kidney function is recommended. Periodic eye examinations are necessary if used for glaucoma. Do not use for prolonged periods without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical carbonic anhydrase inhibitors (e.g., dorzolamide eye drops)

May be used for glaucoma with fewer systemic side effects.

Evidence: Well-established
Beta-blockers (e.g., timolol eye drops)

Another class of medicines for glaucoma.

Evidence: Well-established
Lifestyle modifications for altitude sickness

Gradual ascent and acclimatization can help prevent altitude sickness.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established from the available information. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the dosing schedule. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old man with open-angle glaucoma
He was prescribed this medicine to lower his eye pressure. After taking it for a few weeks, his eye pressure improved significantly. He experienced mild tingling in his fingers, which his doctor said was a common side effect. He made sure to drink plenty of water and took the medicine with meals to avoid stomach upset.
💡 Lesson: Taking this medicine with food and staying hydrated helps manage side effects and improves adherence.
👤 A 35-year-old trekker planning a high-altitude trek
She was advised to take this medicine to prevent acute mountain sickness. She started it 24 hours before her ascent and continued for a few days. She experienced increased urination but no other major issues. The medicine helped her avoid severe altitude sickness and complete her trek safely.
💡 Lesson: This medicine can effectively prevent altitude sickness when taken as prescribed before and during ascent.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 1 to 2 hours after taking a dose. The full effect on eye pressure may take a few hours.

Q: Can I take this medicine with food?

A: Yes, taking it with food helps reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is this medicine safe during pregnancy?

A: This medicine should be used during pregnancy only if the potential benefit justifies the potential risk. Consult your doctor.

Q: Can I drink alcohol while taking this medicine?

A: It is advisable to avoid alcohol as it can increase drowsiness and dizziness.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for iomide 250mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for weight loss.
    Fact: This medicine is a diuretic and can cause temporary fluid loss, but it is not approved for weight loss and can be dangerous if used for that purpose.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription-only medicine and should only be used under medical supervision.
  • Myth: You can stop taking this medicine once your symptoms improve.
    Fact: You should not stop taking this medicine without consulting your doctor, as sudden discontinuation can worsen your condition.

🔄 Alternative Options

Generic Alternatives

  • Acetazolamide 250 mg capsule

Brand Alternatives

  • Iopar-SR Capsule

📊 Comparison with Similar Medicines

[{"medicine":"Acetazolamide","class":"Carbonic anhydrase inhibitor","route":"Oral","main_use":"Glaucoma, edema, epilepsy, altitude sickness"},{"medicine":"Methazolamide","class":"Carbonic anhydrase inhibitor","route":"Oral","main_use":"Glaucoma"},{"medicine":"Dorzolamide","class":"Carbonic anhydrase inhibitor","route":"Ophthalmic","main_use":"Glaucoma"}]

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