actamide 250mg tablet - Acetazolamide (250mg) medicine

Actamide 250mg Tablet - Uses, Price, Side Effects

4.5 (12 reviews)

Acetazolamide (250mg)

🏭 Micro Labs Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is actamide 250mg tablet used for?

Actamide 250mg Tablet contains Acetazolamide, a carbonic anhydrase inhibitor used to treat glaucoma by reducing intraocular pressure and to manage edema due to heart failure or medication. It works by decreasing fluid production in the eye and increasing urine output.

Generic Name: Acetazolamide
Manufacturer: Micro Labs Ltd
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 actamide 250mg tablet Uses & Benefits

Glaucoma (open-angle and secondary); prevention of acute mountain sickness; epilepsy (adjunctive); idiopathic intracranial hypertension; metabolic alkalosis; cystinuria; periodic paralysis.

Off-label uses: Altitude sickness prophylaxis; sleep apnea; glaucoma in dogs; pseudotumor cerebri; diuretic in heart failure (rare).

📋 Drug Information

Generic Name(s)	Acetazolamide
Brand Name	Acetamide
Manufacturer	Micro Labs Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	OPHTHAL
Action Class	Carbonic anhydrase inhibitor
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from gastrointestinal tract after oral administration.

DistributionDistributes into erythrocytes, kidneys, and other tissues; crosses placenta and enters breast milk.

Protein Binding70-90%

MetabolismNot significantly metabolized; excreted unchanged in urine.

Half-Life10-15 hours

ExcretionRenal excretion (90% unchanged)

Bioavailability~100%

Onset of Action1-1.5 hours (oral)

Peak Plasma Time2-4 hours

Duration of Action8-12 hours

How It Works

Inhibits carbonic anhydrase, reducing aqueous humor production in the eye and decreasing intraocular pressure.

Mechanism Steps

1Inhibition of carbonic anhydrase in ciliary processes of the eye

2Reduced formation of bicarbonate ions

3Decreased aqueous humor secretion

💡 How to Take actamide 250mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of actamide 250mg tablet

✅ Common Side Effects

Paresthesia
Taste alteration (metallic taste)
Nausea
Vomiting
Diarrhea
Polyuria
Drowsiness
Confusion

🚨 Serious Side Effects

Stevens-Johnson syndrome
Toxic epidermal necrolysis
Aplastic anemia
Agranulocytosis
Thrombocytopenia
Metabolic acidosis
Hypokalemia
Renal calculi
Hepatic necrosis

⚠️ Rare Side Effects

Photosensitivity
Hearing loss
Tinnitus
Transient myopia
Flaccid paralysis
Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Aspirin	Moderate	Increased risk of metabolic acidosis
Lithium	Major	Decreased lithium excretion, increased toxicity
Metformin	Moderate	Increased risk of lactic acidosis

🚨 Major Interactions

Warfarin
Lithium
Cyclosporine
Methotrexate
Primidone

⚡ Moderate Interactions

Aspirin
Salicylates
Digoxin
Phenytoin
Quinidine

ℹ️ Minor Interactions

Corticosteroids
Amphotericin B
Metformin

🍽️ Food Interactions

High-fat meals may delay absorption; avoid excessive sodium intake.

🍷 Alcohol Interaction

May increase risk of metabolic acidosis and dizziness.

🛡️ Safety & Warnings

Liver

Low

Kidney

Moderate

Heart

Low

Pregnancy

Category C

🚫 Contraindications

Hypersensitivity to acetazolamide or sulfonamides; severe hepatic or renal impairment; hyponatremia; hypokalemia; hyperchloremic acidosis; Addison's disease; long-term use in chronic noncongestive angle-closure glaucoma.

📊 Monitoring Parameters

Intraocular pressure; serum electrolytes (especially potassium and bicarbonate); renal function; liver function; complete blood count; urinary output.

🤱 Lactation Safety

Use with caution; excreted in breast milk.

💊 Overdose Management

Induce emesis or gastric lavage; monitor electrolytes and acid-base balance; treat metabolic acidosis with sodium bicarbonate if severe; supportive care.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for actamide 250mg tablet

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Alternative brands with exact same active ingredient (Acetazolamide (250mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.