aceford max tablet - Thiocolchicoside (4mg) + Aceclofenac (100mg) medicine

Aceford Max Tablet - Uses, Price, Side Effects

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๐Ÿญ Oxford Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 27, 2026

What is aceford max tablet used for?

Aceford Max Tablet is a combination medicine used for the treatment of painful musculoskeletal conditions such as muscle spasms, back pain, and joint pain. It contains Thiocolchicoside, a muscle relaxant, and Aceclofenac, a nonsteroidal anti-inflammatory drug (NSAID). Thiocolchicoside works by blocking nerve signals that cause muscle contractions, while Aceclofenac reduces pain and inflammation by inhibiting prostaglandin synthesis. This dual action provides effective relief from pain and muscle stiffness.

  • Generic Name: Thiocolchicoside + Aceclofenac
  • Manufacturer: Oxford Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š aceford max tablet Uses & Benefits

Acute musculoskeletal pain, muscle spasms, inflammatory conditions

Off-label uses: Not well established

๐Ÿ“‹ Drug Information

Generic Name(s)Thiocolchicoside + Aceclofenac
Brand NameAnaflam TH 4 Tablet
ManufacturerOxford Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassMuscle Relaxant + NSAID
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration
DistributionWidely distributed in body tissues
Protein BindingThiocolchicoside: ~13%; Aceclofenac: >99%
MetabolismThiocolchicoside: Hepatic; Aceclofenac: Hepatic via CYP2C9
Half-LifeThiocolchicoside: ~7 hours; Aceclofenac: ~4 hours
ExcretionThiocolchicoside: Renal (70-80%); Aceclofenac: Renal (70-80%)
BioavailabilityThiocolchicoside: ~25%; Aceclofenac: ~100%
Onset of ActionThiocolchicoside: 30-60 min; Aceclofenac: 30 min
Peak Plasma TimeThiocolchicoside: 1-2 hours; Aceclofenac: 1-3 hours
Duration of ActionThiocolchicoside: 4-6 hours; Aceclofenac: 12-24 hours

How It Works

Thiocolchicoside: Acts on GABA-A and glycine receptors to produce muscle relaxation; Aceclofenac: Inhibits COX-1 and COX-2, reducing prostaglandin synthesis

Mechanism Steps

1Thiocolchicoside binds to GABA-A receptors, enhancing inhibitory neurotransmission
2Thiocolchicoside also acts on glycine receptors, promoting spinal inhibition
3Aceclofenac inhibits cyclooxygenase (COX-1 and COX-2) enzymes

๐Ÿ’ก How to Take aceford max tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of aceford max tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Somnolence

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hepatotoxicity
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Stevens-Johnson syndrome
  • Seizures

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Lithium Moderate Increased lithium toxicity
Aspirin Moderate Increased risk of gastrointestinal bleeding
Methotrexate Major Increased methotrexate toxicity

๐Ÿšจ Major Interactions

  • Warfarin
  • Lithium
  • Methotrexate
  • Aspirin
  • Other NSAIDs

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • Corticosteroids

โ„น๏ธ Minor Interactions

  • Antacids
  • Digoxin
  • Phenytoin

๐Ÿฝ๏ธ Food Interactions

May be taken with food to reduce GI upset

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding and hepatotoxicity

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, active peptic ulcer, severe renal/hepatic impairment, pregnancy (third trimester), lactation, children <16 years

๐Ÿ“Š Monitoring Parameters

Liver function, renal function, blood pressure, GI symptoms

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

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