aceclonac p 100mg/325mg tablet allopathy (Aceclofenac (100mg) + Paracetamol (325mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
aceclonac p 100mg/325mg tablet allopathy (Aceclofenac (100mg) + Paracetamol (325mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Lupin Ltd. Contains Aceclofenac (100mg) + Paracetamol (325mg).

Aceclonac P 100mg/325mg Tablet - Uses, Price, Side Effects

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🏭 Lupin Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is aceclonac p 100mg/325mg tablet used for?

Aceclonac P 100mg/325mg Tablet is a combination of Aceclofenac (100mg) and Paracetamol (325mg) used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Aceclofenac works by blocking the production of prostaglandins, while Paracetamol reduces fever and pain. It is typically taken twice daily after meals.

  • Generic Name: Aceclofenac + Paracetamol
  • Manufacturer: Lupin Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 aceclonac p 100mg/325mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

aceclonac p 100mg/325mg tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Aceclofenac (100mg) + Paracetamol (325mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

📋 Drug Information

Generic Name(s)Aceclofenac + Paracetamol
Brand NameAldigesic P
ManufacturerLupin Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in tissues
Protein BindingAceclofenac: >99%; Paracetamol: 10-25%
MetabolismAceclofenac: hepatic via CYP2C9; Paracetamol: hepatic via glucuronidation and sulfation
Half-LifeAceclofenac: 4-5 h; Paracetamol: 2-3 h
ExcretionRenal (primarily urine)
BioavailabilityAceclofenac: ~100%; Paracetamol: ~88%
Onset of Action30-60 minutes
Peak Plasma TimeAceclofenac: 1-3 h; Paracetamol: 0.5-2 h
Duration of Action4-6 hours

Pharmacodynamics

Mechanism of ActionAceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.
Target ReceptorCyclooxygenase (COX) enzymes
Pharmacodynamic EffectsAnalgesic, anti-inflammatory, antipyretic

📅 When to take aceclonac p 100mg/325mg tablet?

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

💡 How and when to take aceclonac p 100mg/325mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture.

⚙️ How aceclonac p 100mg/325mg tablet Works

Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.

1 Aceclofenac inhibits COX-1 and COX-2, decreasing prostaglandin synthesis.
⬇️
2 Reduced prostaglandins lead to decreased inflammation and pain.
⬇️
3 Paracetamol inhibits COX in the CNS, reducing pain signal transmission.
⬇️
4 Paracetamol acts on hypothalamic heat-regulating center to reduce fever.
⬇️
5 Combined effect provides enhanced analgesia and antipyresis.

💊 aceclonac p 100mg/325mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, dysmenorrhea, fever.

Off-label uses: Postoperative pain, migraine (limited evidence).

⚠️ What are the side effects of aceclonac p 100mg/325mg tablet?

✅ Common Side Effects

  • Nausea
  • Dizziness
  • Drowsiness
  • Rash
  • GI upset

🚨 Serious Side Effects

  • GI bleeding
  • Hepatotoxicity
  • Renal failure
  • Stevens-Johnson syndrome

⚠️ Rare Side Effects

  • Blood dyscrasias
  • Anaphylaxis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for aceclonac p 100mg/325mg tablet

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Alternative medicines with exact same composition and strength (Aceclofenac (100mg) + Paracetamol (325mg)):

  1. rumatab sp 100 mg/325 mg/15 mg tablet
    Simpson Brawn Pharmaceuticals₹5.23💰 89.9% CHEAPER
  2. aclopen plus 100mg/325mg tablet
    Morepen Laboratories Ltd₹6.44💰 87.5% CHEAPER
  3. dolospark 100mg/325mg tablet
    Spark Medicare Pvt Ltd₹7.31💰 85.8% CHEAPER
  4. aceforce mr 100 mg/325 mg/250 mg tablet
    Shreya Life Sciences Pvt Ltd₹10.55💰 79.5% CHEAPER
  5. asozen-plus tablet
    Zeelab Pharmacy Pvt Ltd₹11.00💰 78.7% CHEAPER
  6. acefex p 100mg/325mg tablet
    Zydus Cadila₹11.25💰 78.2% CHEAPER
  7. afecox 100 mg/325 mg tablet
    Apostle Remedies₹12.19💰 76.4% CHEAPER
  8. aceclofast tablet
    Wings Biotech Ltd₹12.90💰 75% CHEAPER
  9. dolospark-sp tablet
    Spark Medicare Pvt Ltd₹13.13💰 74.5% CHEAPER
  10. nicoace mr tablet
    Abbott₹15.00💰 70.9% CHEAPER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Aspirin Moderate Increased risk of gastrointestinal bleeding
Lithium Moderate Increased lithium levels
ACE inhibitors Minor Reduced antihypertensive effect

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • Aspirin

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • SSRIs

ℹ️ Minor Interactions

  • Antacids
  • Cholestyramine

🍽️ Food Interactions

Food may delay absorption; avoid alcohol.

🍷 Alcohol Interaction

Increased risk of hepatotoxicity (paracetamol) and GI bleeding (aceclofenac).

🛡️ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

🚫 Contraindications

Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, history of asthma with NSAIDs.

📊 Monitoring Parameters

Liver function tests, renal function, CBC, blood pressure.

🤱 Lactation Safety

Caution; paracetamol is safe, aceclofenac may be excreted in small amounts.

💊 Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for aceclofenac.

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

🛑 Myths vs. Facts about aceclonac p 100mg/325mg tablet

  • Myth: Generic substitutes of aceclonac p 100mg/325mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Aceclofenac (100mg) + Paracetamol (325mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of aceclonac p 100mg/325mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

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